Protein Overview: FBpp0309199, Nup...

General Information:
Name(s) found:	FBpp0309200 [FlyBase] FBpp0309199 [FlyBase] Nup154-PA / FBpp0088820 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7297801\|gb\|AAF53051.1\| Nup154, isoform A [Drosophila melanogaster] [NCBI NR] gi\|5679156\|gb\|AAD46884.1\|AF160944_1 Nup154 [Drosophila melanogaster] [NCBI NR] gi\|17316372\|ref\|NP_477287.1\| Nup154, isoform A [Drosophila melanogaster] [NCBI NR] type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0309200; name=Nup154-PD; parent=FBgn0021761,FBtr0340225; dbxref=FlyBase:FBpp0309200,FlyBase_Annotation_IDs:CG4579-PD; MD5=8bf36baa6bf56a83ca21025128914ed8; length=1365; release=r5.56; species=Dmel; [FlyBase] type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0309199; name=Nup154-PC; parent=FBgn0021761,FBtr0340224; dbxref=FlyBase:FBpp0309199,FlyBase_Annotation_IDs:CG4579-PC; MD5=8bf36baa6bf56a83ca21025128914ed8; length=1365; release=r5.56; species=Dmel; [FlyBase] The gene Nup154 is referred to in FlyBase by the symbol Dmel\Nup154 (CG4579, FBgn0021761). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:11004823..11009878. It has the cytological map location 32C1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: structural constituent of nuclear pore. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: nucleocytoplasmic transport. 25 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system; anatomical structure; female germline cyst; egg; nervous system; male germline cyst; embryonic/larval hemocoel; spermatocyte; elongation stage spermatid; imaginal precursor; adult segment. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG4579-PA translation from_gene[CG4579 Nup154 FBgn0021761] seq_release:3 mol_weight=153897 cds_boundaries:(2L:10,997,389..11,002,165[+]) aa_length:1365 transcript_info:[CG4579-RA seq_release:3] gene_info:[gene symbol:Nup154 FBgn0021761 gene_boundaries [hmr_yeast5_DM3-1_pombe.fasta] (Q9V463) NUP154 protein [DrosMelano7227.FASTAC.txt] (AE003630) Nup154 gene product [alt 2] [Drosophila melanogaster] [yeastflysequest.fasta] CG4579-PA, isoform A [Drosophila melanogaster]gi\|5679156\|gb\|AAD46884.1\| Nup154 [Drosophila melanogaster]gi\|17316372\|ref\|NP_477287.1\| CG4579-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); [fly-100309-contam.fasta] Nup154 [Drosophila melanogaster] [nr-271106-contam.fasta] CG4579-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] Nup154 CG4579-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0088820; name=Nup154-PA; parent=FBgn0021761,FBtr0089881; dbxref=FlyBase:FBpp0088820,FlyBase_Annotation_IDs:CG4579-PA,GB_protein:AAF53051.1,REFSEQ:NP_477287,GB_protein:AAF53051; MD5=8bf36baa6bf56a83ca21025128914ed8; length=1365; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0088820; name=Nup154-PA; parent=FBgn0021761,FBtr0089881; dbxref=FlyBase:FBpp0088820,FlyBase_Annotation_IDs:CG4579-PA,GB_protein:AAF53051.1,REFSEQ:NP_477287,GB_protein:AAF53051; MD5=8bf36baa6bf56a83ca21025128914ed8; length=1365; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Nup154 OS=Drosophila melanogaster GN=Nup154 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0088820; name=Nup154-PA; parent=FBgn0021761,FBtr0089881; dbxref=FlyBase:FBpp0088820,FlyBase_Annotation_IDs:CG4579-PA,GB_protein:AAF53051.1,REFSEQ:NP_477287,GB_protein:AAF53051,FlyMine:FBpp0088820,modMine:FBpp0088820; MD5=8bf36baa6bf56a83ca21025128914ed8; length=1365; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0088820; name=Nup154-PA; parent=FBgn0021761,FBtr0089881; dbxref=FlyBase:FBpp0088820,FlyBase_Annotation_IDs:CG4579-PA,GB_protein:AAF53051.1,REFSEQ:NP_477287,GB_protein:AAF53051,FlyMine:FBpp0088820,modMine:FBpp0088820; MD5=8bf36baa6bf56a83ca21025128914ed8; length=1365; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0309199; name=Nup154-PC; parent=FBgn0021761,FBtr0340224; dbxref=FlyBase:FBpp0309199,FlyBase_Annotation_IDs:CG4579-PC,GB_protein:AAF53050,REFSEQ:NP_477288; MD5=8bf36baa6bf56a83ca21025128914ed8; length=1365; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0309200; name=Nup154-PD; parent=FBgn0021761,FBtr0340225; dbxref=FlyBase:FBpp0309200,FlyBase_Annotation_IDs:CG4579-PD,GB_protein:AHN54341,REFSEQ:NP_001285827; MD5=8bf36baa6bf56a83ca21025128914ed8; length=1365; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0088820; name=Nup154-PA; parent=FBgn0021761,FBtr0089881; dbxref=FlyBase:FBpp0088820,FlyBase_Annotation_IDs:CG4579-PA,GB_protein:AAF53051.1,REFSEQ:NP_477287,GB_protein:AAF53051,FlyMine:FBpp0088820,modMine:FBpp0088820; MD5=8bf36baa6bf56a83ca21025128914ed8; length=1365; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0309199; name=Nup154-PC; parent=FBgn0021761,FBtr0340224; dbxref=FlyBase:FBpp0309199,FlyBase_Annotation_IDs:CG4579-PC,GB_protein:AAF53050,REFSEQ:NP_477288; MD5=8bf36baa6bf56a83ca21025128914ed8; length=1365; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0309200; name=Nup154-PD; parent=FBgn0021761,FBtr0340225; dbxref=FlyBase:FBpp0309200,FlyBase_Annotation_IDs:CG4579-PD,GB_protein:AHN54341,REFSEQ:NP_001285827; MD5=8bf36baa6bf56a83ca21025128914ed8; length=1365; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Nucleoporin 154kD, isoform A OS=Drosophila melanogaster GN=Nup154 PE=1 SV=1 [DROME.fasta.20160308] FBpp0088820 type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0088820; name=Nup154-PA; parent=FBgn0021761,FBtr0089881; dbxref=FlyBase:FBpp0088820,FlyBase_Annotation_IDs:CG4579-PA,GB_protein:AAF53051.1,REFSEQ:NP_477287,GB_protein:AAF53051,FlyMine:FBpp0088820,modMine:FBpp0088820; MD5=8bf36baa6bf56a83ca21025128914ed8; length=1365; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0309199 type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0309199; name=Nup154-PC; parent=FBgn0021761,FBtr0340224; dbxref=FlyBase:FBpp0309199,FlyBase_Annotation_IDs:CG4579-PC,GB_protein:AAF53050,REFSEQ:NP_477288; MD5=8bf36baa6bf56a83ca21025128914ed8; length=1365; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0309200 type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0309200; name=Nup154-PD; parent=FBgn0021761,FBtr0340225; dbxref=FlyBase:FBpp0309200,FlyBase_Annotation_IDs:CG4579-PD,GB_protein:AHN54341,REFSEQ:NP_001285827; MD5=8bf36baa6bf56a83ca21025128914ed8; length=1365; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0088820; name=Nup154-PA; parent=FBgn0021761,FBtr0089881; dbxref=FlyBase:FBpp0088820,FlyBase_Annotation_IDs:CG4579-PA,GB_protein:AAF53051.1,REFSEQ:NP_477287,GB_protein:AAF53051,UniProt/TrEMBL:Q9V463,FlyMine:FBpp0088820,modMine:FBpp0088820; MD5=8bf36baa6bf56a83ca21025128914ed8; length=1365; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0309199; name=Nup154-PC; parent=FBgn0021761,FBtr0340224; dbxref=FlyBase:FBpp0309199,FlyBase_Annotation_IDs:CG4579-PC,GB_protein:AAF53050,REFSEQ:NP_477288,UniProt/TrEMBL:Q9V463; MD5=8bf36baa6bf56a83ca21025128914ed8; length=1365; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=2L:join(11004980..11005078,11005139..11005301,11005368..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0309200; name=Nup154-PD; parent=FBgn0021761,FBtr0340225; dbxref=FlyBase:FBpp0309200,FlyBase_Annotation_IDs:CG4579-PD,GB_protein:AHN54341,REFSEQ:NP_001285827,UniProt/TrEMBL:Q9V463; MD5=8bf36baa6bf56a83ca21025128914ed8; length=1365; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1365 amino acids
Gene Ontology:
Cellular Component:	nuclear envelope [IDA] nucleus [IDA] nuclear pore [IEA][ISS][NAS]
Biological Process:	nucleocytoplasmic transport [IEA]
Molecular Function:	protein binding [IEA] structural constituent of nuclear pore [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLPQAQLDF FTTATSMLEW HYNLERNKPG LLELTGVSQH GRATMSGLND YDYQSLSFLK  60
   61 SDRTHNLQQM RTVTKSAIPN EILEHFKHIK CHCTMGLFPE IGRAWLTIDS EIYIWTFNQT 120
  121 RDVAYYDGLS HLIVSVGLVK PKPGVFVQDV KYLLVLTTPI EVIVLGVTFG ESSYNEMQLM 180
  181 NRPVFVIGTD NVSISVIKGT DDGRIFLGGR DGCLYEIYYQ AESSWFGKRC KKINLSQGLV 240
  241 SYMVPSFLKV FSEVDPIEHI EIDNSRKLLY VLTEKGVIEA WDISTSYTTA RRLGRITQND 300
  301 ITNQAVSLIT TVDPSIFKSV KAICPLSADD ADKLHLVAVT QCGVRLFFST TSLNVKQQFG 360
  361 PAVPCSPGEN TGFGQPAVQP PLSPNAEAPK GLYLLHVRLP PGYTPNATTN KPKQVHAAHY 420
  421 TEGTMLMITT QQHEQDLLWS LSSAPSVNFT YLVESTALES LDGVVWGLAE VHEPSTPQRK 480
  481 SPLNSARHAR KVALLTNQGT HIIEVLKMVD VLRQILLSCN GPHHEEVKMF FQSQNQREAC 540
  541 VTALLLATSD TYRGSDVALW AAQAFMLYGG EPCYQHQKFL NASNRNMANQ TLGPNTTNVR 600
  601 ERQSMFMSTP MPNSVANSPV GFPGSQFNQP ISPIGNMQPP QVAVSNENSP IVFSAKHDGL 660
  661 YMYVSRMLHS VWQMRCVNEQ FCSNLSQSEC ALLLSDLRSL RSFLEVHSVH DISSTTRVSF 720
  721 DNHLDRTNSY NTIMMGNTLL PIPEQRVLSE QAQVEETRSL SALNLFVKHA CEVISLWNIL 780
  781 NSHSFQLICV QLSPEHQKLL TCSTFRDLLI TRSEVCAFLI ISLINLYLKD AAGVSEVSKN 840
  841 LRENCPNLYR HEDDVTYKAT ELLMNAKNCT SATEKEHMLR TTLHMCKEAA PTLPLHSICM 900
  901 QFISADFFEG VIELSAVCAS KSDPEEVGVH FYNNGEPADD REGYTCFATR MAYYKEVQLM 960
  961 LDHIYQRVCN KTHVQDKSIN PLKGTAKASD AKNGATQTIP KIVAHTLKVK DPLIHITLYE1020
 1021 WLLAHDMLKE LLDVVEPSLG EFLRRSVSQN VDNVVLIDLL WKYYEKNSHH SQAAHILDNL1080
 1081 AMTRSENINL EQRIEYLVRA VMCMRNGNVG SSLSNGIFLK ELEDKLDIAR VQKSVLAAMT1140
 1141 ELASDKLEAA TAVKELNYAL YDITQLYQHF AEPFDLWECQ LSILNCSHHN DPLLIESVWG1200
 1201 QIINSVVDKP GTTSERCNRL FTKIEILVRE YGESGVCFPF AFLIRELEVK ACQLRFPEGI1260
 1261 VPEKLVSMNL DIELLLEYYS RMISMNERVW ANEGNEWHLI QSVIRVVSLL ADNAQSIWYR1320
 1321 SKRRIVGKAQ DIVAGCLNIC YQKPDTNRLQ HSLKELQSQL QRLLI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: FBpp0309199, Nup...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: