Protein Overview: Nup154-PB

General Information:
Name(s) found:	Nup154-PB / FBpp0088821 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|24583605\|ref\|NP_477288.2\| Nup154, isoform B [Drosophila melanogaster] [NCBI NR] gi\|22946221\|gb\|AAF53050.2\| Nup154, isoform B [Drosophila melanogaster] [NCBI NR] The gene Nup154 is referred to in FlyBase by the symbol Dmel\Nup154 (CG4579, FBgn0021761). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:11004823..11009878. It has the cytological map location 32C1. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: structural constituent of nuclear pore. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: nucleocytoplasmic transport. 25 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system; anatomical structure; female germline cyst; egg; nervous system; male germline cyst; embryonic/larval hemocoel; spermatocyte; elongation stage spermatid; imaginal precursor; adult segment. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG4579-PB translation from_gene[CG4579 Nup154 FBgn0021761] seq_release:3 mol_weight=126420 cds_boundaries:(2L:10,998,241..11,002,165[+]) aa_length:1123 transcript_info:[CG4579-RB seq_release:3] gene_info:[gene symbol:Nup154 FBgn0021761 gene_boundaries [hmr_yeast5_DM3-1_pombe.fasta] (Q9VKL5) CG4579 protein [DrosMelano7227.FASTAC.txt] CG4579-PB, isoform B [Drosophila melanogaster]gi\|24583605\|ref\|NP_477288.2\| CG4579-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:join(11005832..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0088821; name=Nup154-PB; paren [fly-100309-contam.fasta] Nup154 CG4579-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] CG4579-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2L:join(11005832..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0088821; name=Nup154-PB; parent=FBgn0021761,FBtr0089882; dbxref=FlyBase:FBpp0088821,FlyBase_Annotation_IDs:CG4579-PB,GB_protein:AAF53050.2,REFSEQ:NP_477288,GB_protein:AAF53050; MD5=472db664571023d0d9fbacc4218a3d77; length=1123; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:join(11005832..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0088821; name=Nup154-PB; parent=FBgn0021761,FBtr0089882; dbxref=FlyBase:FBpp0088821,FlyBase_Annotation_IDs:CG4579-PB,GB_protein:AAF53050.2,REFSEQ:NP_477288,GB_protein:AAF53050; MD5=472db664571023d0d9fbacc4218a3d77; length=1123; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Nup154, isoform B OS=Drosophila melanogaster GN=Nup154 PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2L:join(11005832..11005861,11005921..11006093,11006162..11007132,11007192..11007431,11007495..11007656,11007715..11008261,11008320..11008845,11008911..11009377,11009443..11009565,11009627..11009759); ID=FBpp0088821; name=Nup154-PB; parent=FBgn0021761,FBtr0089882; dbxref=FlyBase:FBpp0088821,FlyBase_Annotation_IDs:CG4579-PB,GB_protein:AAF53050.2,REFSEQ:NP_477288,GB_protein:AAF53050,FlyMine:FBpp0088821,modMine:FBpp0088821; MD5=472db664571023d0d9fbacc4218a3d77; length=1123; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
Organism:	Drosophila melanogaster
Length:	1123 amino acids
Gene Ontology:
Cellular Component:	nuclear envelope [IDA] nucleus [IDA] nuclear pore [IEA][ISS][NAS]
Biological Process:	nucleocytoplasmic transport [IEA]
Molecular Function:	protein binding [IEA] structural constituent of nuclear pore [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVPSFLKVFS EVDPIEHIEI DNSRKLLYVL TEKGVIEAWD ISTSYTTARR LGRITQNDIT  60
   61 NQAVSLITTV DPSIFKSVKA ICPLSADDAD KLHLVAVTQC GVRLFFSTTS LNVKQQFGPA 120
  121 VPCSPGENTG FGQPAVQPPL SPNAEAPKGL YLLHVRLPPG YTPNATTNKP KQVHAAHYTE 180
  181 GTMLMITTQQ HEQDLLWSLS SAPSVNFTYL VESTALESLD GVVWGLAEVH EPSTPQRKSP 240
  241 LNSARHARKV ALLTNQGTHI IEVLKMVDVL RQILLSCNGP HHEEVKMFFQ SQNQREACVT 300
  301 ALLLATSDTY RGSDVALWAA QAFMLYGGEP CYQHQKFLNA SNRNMANQTL GPNTTNVRER 360
  361 QSMFMSTPMP NSVANSPVGF PGSQFNQPIS PIGNMQPPQV AVSNENSPIV FSAKHDGLYM 420
  421 YVSRMLHSVW QMRCVNEQFC SNLSQSECAL LLSDLRSLRS FLEVHSVHDI SSTTRVSFDN 480
  481 HLDRTNSYNT IMMGNTLLPI PEQRVLSEQA QVEETRSLSA LNLFVKHACE VISLWNILNS 540
  541 HSFQLICVQL SPEHQKLLTC STFRDLLITR SEVCAFLIIS LINLYLKDAA GVSEVSKNLR 600
  601 ENCPNLYRHE DDVTYKATEL LMNAKNCTSA TEKEHMLRTT LHMCKEAAPT LPLHSICMQF 660
  661 ISADFFEGVI ELSAVCASKS DPEEVGVHFY NNGEPADDRE GYTCFATRMA YYKEVQLMLD 720
  721 HIYQRVCNKT HVQDKSINPL KGTAKASDAK NGATQTIPKI VAHTLKVKDP LIHITLYEWL 780
  781 LAHDMLKELL DVVEPSLGEF LRRSVSQNVD NVVLIDLLWK YYEKNSHHSQ AAHILDNLAM 840
  841 TRSENINLEQ RIEYLVRAVM CMRNGNVGSS LSNGIFLKEL EDKLDIARVQ KSVLAAMTEL 900
  901 ASDKLEAATA VKELNYALYD ITQLYQHFAE PFDLWECQLS ILNCSHHNDP LLIESVWGQI 960
  961 INSVVDKPGT TSERCNRLFT KIEILVREYG ESGVCFPFAF LIRELEVKAC QLRFPEGIVP1020
 1021 EKLVSMNLDI ELLLEYYSRM ISMNERVWAN EGNEWHLIQS VIRVVSLLAD NAQSIWYRSK1080
 1081 RRIVGKAQDI VAGCLNICYQ KPDTNRLQHS LKELQSQLQR LLI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: Nup154-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: