Protein Overview: CYLD-PE, CYLD-PD

General Information:
Name(s) found:	CYLD-PE / FBpp0079660 [FlyBase] CYLD-PD / FBpp0079659 [FlyBase]
Description(s) found: Found 34 descriptions. SHOW ALL	The gene cylindromatosis is referred to in FlyBase by the symbol Dmel\CYLD (CG5603, FBgn0032210). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:10295856..10299827. It has the cytological map location 31C7-31D1. There is experimental evidence that it has the molecular function</span>: ubiquitin-specific protease activity. There is experimental evidence that it is involved in the biological process</span>: protein deubiquitination; defense response to bacterium; acylglycerol homeostasis. 8 alleles are reported. The phenotypes of these alleles are annotated with: adult fat body; lipid particle. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] The gene cylindromatosis is referred to in FlyBase by the symbol Dmel\CYLD (CG5603, FBgn0032210). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:10295856..10299827. It has the cytological map location 31C7-31D1. There is experimental evidence that it has the molecular function</span>: ubiquitin-specific protease activity. There is experimental evidence that it is involved in the biological process</span>: protein deubiquitination; defense response to bacterium; acylglycerol homeostasis. 8 alleles are reported. The phenotypes of these alleles are annotated with: adult fat body; lipid particle. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	639 amino acids
Gene Ontology:
Cellular Component:	nucleus [ISS] ribosome [IEA]
Biological Process:	protein deubiquitination [IDA] acylglycerol homeostasis [IMP] defense response to bacterium [IMP] ubiquitin-dependent protein catabolic process [IEA] translation [IEA]
Molecular Function:	ubiquitin-specific protease activity [IDA] transcription factor activity [ISS] structural constituent of ribosome [IEA] ubiquitin thiolesterase activity [IEA][ISS] microtubule binding [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSKSDYEAE KEKKLTITNR FGDSLENYEL SNESEHKTHV YPKKIPNRKN GILKNTDANH  60
   61 SAVDNQHLED VDLADILGTN WPKRAGPAAM ILNNKSKTDP SNSVDLILKP ASPILKIEPE 120
  121 EPLRFTIADY QPLIEIPGTE LAIGSLVEVS NPGVCEDLYG VVRWIGIPPG PQKNVLVGIE 180
  181 VEDESNLKNV VASDGRHNGV RLFTCHDGRA IFVPANRCTA DRRFADVDNS ISANRVSSNH 240
  241 AKKFGVADCP AIYGSIPPLQ IHNSDELASI CGKFKGIQGH HNSCYLDATL FSMFTFTSVF 300
  301 DSILYRRPGP QDIRNYSEVQ KVLRDEIVNP LRKNVFVRSD RVMKLRELLD QLSSVSGLTC 360
  361 EEKDPEEFLN SLLSQIMRVE PFLKLSSGQD SYFYQLFVEK DEKLTLPSVQ QLFEQSFHSS 420
  421 DIKLKEVPSC FIIQMPRFGK NYKMYPRILP SQVLDVTDII ENSPRQCSLC GKLAEYECRD 480
  481 CFGSLQAGSG LECTAFCPKC LKTFHSHIKR TNHVSKKIYS PKEFKIMAEH MVVPRLYMEL 540
  541 FAVVCIETSH YVAFVKSGSG PDAPWCFFDS MADRKGEQNG YNIPEITCVP ELTQWLSEEG 600
  601 ARSINETSTN DKVLPEHAKR IFCDAYMCLY QSTDIMMYH

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: CYLD-PE, CYLD-PD

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: