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Protein Overview: FBpp0309663, FKB...

General Information:
Name(s) found: FBpp0309663 [FlyBase]
FKBP59-PA / FBpp0079468 [FlyBase]
Description(s) found:
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  • gi|74869710|sp|Q9VL78.1|FKB59_DROME RecName: Full=FK506-binding protein 59; AltName: Full=Peptidyl-prolyl cis-trans isomerase; Short=PPIase; Short=Rotamase; AltName: Full=dFKBP59 [NCBI NR]
  • gi|7297564|gb|AAF52818.1| FK506-binding protein FKBP59 [Drosophila melanogaster] [NCBI NR]
  • gi|24583150|ref|NP_524895.2| FK506-binding protein FKBP59 [Drosophila melanogaster] [NCBI NR]
  • gi|16198261|gb|AAL13958.1| LD47530p [Drosophila melanogaster] [NCBI NR]
  • FK506-binding protein 59 OS=Drosophila melanogaster GN=FKBP59 PE=1 SV=1 [Swiss-Prot]
  • type=protein; loc=2L:join(9888143..9888338,9888404..9888546,9888667..9888787,9888847..9888985,9889048..9889405,9889460..9889570,9889632..9889769,9889877..9889990); ID=FBpp0309663; name=FKBP59-PB; parent=FBgn0029174,FBtr0342837; dbxref=FlyBase:FBpp0309663,FlyBase_Annotation_IDs:CG4535-PB; MD5=0cba52e8ed40bf222c6e1861d81c13b2; length=439; release=r5.56; species=Dmel; [FlyBase]
  • The gene FK506-binding protein FKBP59 is referred to in FlyBase by the symbol Dmel\FKBP59 (CG4535, FBgn0029174). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:9888034..9890120. It has the cytological map location 30E1. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: regulation of calcium ion transport; detection of light stimulus involved in visual perception. 6 alleles are reported. The phenotypes of these alleles are annotated with: plasmatocyte; fascicle; embryonic peripheral nervous system; crystal cell. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG4535-PA translation from_gene[CG4535 FKBP59 FBgn0029174] seq_release:3 mol_weight=48796 cds_boundaries:(2L:9,880,372..9,882,216[+]) aa_length:439 transcript_info:[CG4535-RA seq_release:3] gene_info:[gene symbol:FKBP59 FBgn0029174 gene_boundaries:(2L [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VL78) CG4535 protein (LD47530P) [DrosMelano7227.FASTAC.txt]
  • (AE003626) FKBP59-bp1 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG4535-PA [Drosophila melanogaster]gi|16198261|gb|AAL13958.1| LD47530p [Drosophila melanogaster]gi|24583150|ref|NP_524895.2| CG4535-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2L:join(9888143..9888338,9888404..9888546,9888667..9888787,9888847..9888985,9889048..9889405,9889460..9889570,9889632..9889769,9889877..9889990); ID=FBpp0079468; name=FKBP59-PA; parent=FBgn0029174,FBtr0079872; dbxref=GB_protein:AAF52818. [fly-100309-contam.fasta]
  • FK506-binding protein FKBP59 CG4535-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG4535-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • LD47530p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • FK506-binding protein 59 (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (dFKBP59) [nr-271106-contam.fasta]
  • type=protein; loc=2L:join(9888143..9888338,9888404..9888546,9888667..9888787,9888847..9888985,9889048..9889405,9889460..9889570,9889632..9889769,9889877..9889990); ID=FBpp0079468; name=FKBP59-PA; parent=FBgn0029174,FBtr0079872; dbxref=GB_protein:AAF52818.1,FlyBase:FBpp0079468,FlyBase_Annotation_IDs:CG4535-PA,REFSEQ:NP_524895,GB_protein:AAF52818; MD5=0cba52e8ed40bf222c6e1861d81c13b2; length=439; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:join(9888143..9888338,9888404..9888546,9888667..9888787,9888847..9888985,9889048..9889405,9889460..9889570,9889632..9889769,9889877..9889990); ID=FBpp0079468; name=FKBP59-PA; parent=FBgn0029174,FBtr0079872; dbxref=GB_protein:AAF52818.1,FlyBase:FBpp0079468,FlyBase_Annotation_IDs:CG4535-PA,REFSEQ:NP_524895,GB_protein:AAF52818; MD5=0cba52e8ed40bf222c6e1861d81c13b2; length=439; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=2L:join(9888143..9888338,9888404..9888546,9888667..9888787,9888847..9888985,9889048..9889405,9889460..9889570,9889632..9889769,9889877..9889990); ID=FBpp0079468; name=FKBP59-PA; parent=FBgn0029174,FBtr0079872; dbxref=GB_protein:AAF52818.1,FlyBase:FBpp0079468,FlyBase_Annotation_IDs:CG4535-PA,REFSEQ:NP_524895,GB_protein:AAF52818,FlyMine:FBpp0079468,modMine:FBpp0079468; MD5=0cba52e8ed40bf222c6e1861d81c13b2; length=439; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:join(9888143..9888338,9888404..9888546,9888667..9888787,9888847..9888985,9889048..9889405,9889460..9889570,9889632..9889769,9889877..9889990); ID=FBpp0079468; name=FKBP59-PA; parent=FBgn0029174,FBtr0079872; dbxref=GB_protein:AAF52818.1,FlyBase:FBpp0079468,FlyBase_Annotation_IDs:CG4535-PA,REFSEQ:NP_524895,GB_protein:AAF52818,FlyMine:FBpp0079468,modMine:FBpp0079468; MD5=0cba52e8ed40bf222c6e1861d81c13b2; length=439; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:join(9888143..9888338,9888404..9888546,9888667..9888787,9888847..9888985,9889048..9889405,9889460..9889570,9889632..9889769,9889877..9889990); ID=FBpp0309663; name=FKBP59-PB; parent=FBgn0029174,FBtr0342837; dbxref=GB_protein:AHN54298,REFSEQ:NP_001285784,FlyBase:FBpp0309663,FlyBase_Annotation_IDs:CG4535-PB; MD5=0cba52e8ed40bf222c6e1861d81c13b2; length=439; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:join(9888143..9888338,9888404..9888546,9888667..9888787,9888847..9888985,9889048..9889405,9889460..9889570,9889632..9889769,9889877..9889990); ID=FBpp0079468; name=FKBP59-PA; parent=FBgn0029174,FBtr0079872; dbxref=GB_protein:AAF52818.1,FlyBase:FBpp0079468,FlyBase_Annotation_IDs:CG4535-PA,REFSEQ:NP_524895,GB_protein:AAF52818,FlyMine:FBpp0079468,modMine:FBpp0079468; MD5=0cba52e8ed40bf222c6e1861d81c13b2; length=439; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=2L:join(9888143..9888338,9888404..9888546,9888667..9888787,9888847..9888985,9889048..9889405,9889460..9889570,9889632..9889769,9889877..9889990); ID=FBpp0309663; name=FKBP59-PB; parent=FBgn0029174,FBtr0342837; dbxref=GB_protein:AHN54298,REFSEQ:NP_001285784,FlyBase:FBpp0309663,FlyBase_Annotation_IDs:CG4535-PB; MD5=0cba52e8ed40bf222c6e1861d81c13b2; length=439; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9VL78, FK506-binding protein FKBP59, isoform B OS=Drosophila melanogaster GN=FKBP59 PE=4 SV=1 [DROME.fasta.20160308]
  • FBpp0079468 type=protein; loc=2L:join(9888143..9888338,9888404..9888546,9888667..9888787,9888847..9888985,9889048..9889405,9889460..9889570,9889632..9889769,9889877..9889990); ID=FBpp0079468; name=FKBP59-PA; parent=FBgn0029174,FBtr0079872; dbxref=GB_protein:AAF52818.1,FlyBase:FBpp0079468,FlyBase_Annotation_IDs:CG4535-PA,REFSEQ:NP_524895,GB_protein:AAF52818,FlyMine:FBpp0079468,modMine:FBpp0079468; MD5=0cba52e8ed40bf222c6e1861d81c13b2; length=439; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0309663 type=protein; loc=2L:join(9888143..9888338,9888404..9888546,9888667..9888787,9888847..9888985,9889048..9889405,9889460..9889570,9889632..9889769,9889877..9889990); ID=FBpp0309663; name=FKBP59-PB; parent=FBgn0029174,FBtr0342837; dbxref=GB_protein:AHN54298,REFSEQ:NP_001285784,FlyBase:FBpp0309663,FlyBase_Annotation_IDs:CG4535-PB; MD5=0cba52e8ed40bf222c6e1861d81c13b2; length=439; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2L:join(9888143..9888338,9888404..9888546,9888667..9888787,9888847..9888985,9889048..9889405,9889460..9889570,9889632..9889769,9889877..9889990); ID=FBpp0079468; name=FKBP59-PA; parent=FBgn0029174,FBtr0079872; dbxref=GB_protein:AAF52818.1,FlyBase:FBpp0079468,FlyBase_Annotation_IDs:CG4535-PA,REFSEQ:NP_524895,GB_protein:AAF52818,UniProt/Swiss-Prot:Q9VL78,FlyMine:FBpp0079468,modMine:FBpp0079468; MD5=0cba52e8ed40bf222c6e1861d81c13b2; length=439; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=2L:join(9888143..9888338,9888404..9888546,9888667..9888787,9888847..9888985,9889048..9889405,9889460..9889570,9889632..9889769,9889877..9889990); ID=FBpp0309663; name=FKBP59-PB; parent=FBgn0029174,FBtr0342837; dbxref=GB_protein:AHN54298,REFSEQ:NP_001285784,FlyBase:FBpp0309663,FlyBase_Annotation_IDs:CG4535-PB,UniProt/Swiss-Prot:Q9VL78; MD5=0cba52e8ed40bf222c6e1861d81c13b2; length=439; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 439 amino acids

    Gene Ontology:
    Cellular Component: inaD signaling complex [IPI]
    Biological Process: detection of light stimulus involved in visual perception [IPI]
    peripheral nervous system development [TAS]
    regulation of calcium ion transport [IDA]
    protein folding [IEA]
    Molecular Function: peptidyl-prolyl cis-trans isomerase activity [ISS]
    protein binding [IPI]
    FK506 binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPEGNKIDLS GDGGVLKEIL KEGTGTETPH SGCTVSLHYT GRLVDGTEFD SSLSRNEPFE  60
   61 FSLGKGNVIK AFDMGVATMK LGERCFLTCA PNYAYGAAGS PPAIPPDATL IFELEMLGWK 120
  121 GEDLSPNQDG SIDRTILEAS DKKRTPSDGA FVKAHISGSF EGRVFEDRDV EFDYGEGKAI 180
  181 GIIDGVEIAL EKMNVGETSR IKIQAKYAFG AKGNEEFKIP PNATVEYTVK LVDCGKGLEE 240
  241 WKLSDEERLA EAKVYKEKGT NYFKKENWAL AIKMYTKCKN ILPTTVHTNE EVKKIKVATH 300
  301 SNIALCHQKS NDHFEAKQEC NEVLALDKNN VKALYRRGQC NLTINELEDA LEDFQKVIQL 360
  361 EPGNKAAANQ VIICKQKLKE SKNKEKKLYA NMFTKLAAND KETEPPRETD VLSKCGEWSE 420
  421 EDAKREAELT LERDNIIMI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle