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Protein Overview: CG4389-PB

General Information:
Name(s) found: CG4389-PB / FBpp0079453 [FlyBase]
Description(s) found:
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  • gi|24583079|ref|NP_723471.1| CG4389, isoform C [Drosophila melanogaster] [NCBI NR]
  • gi|24583077|ref|NP_723470.1| CG4389, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|22946040|gb|AAN10698.1| CG4389, isoform C [Drosophila melanogaster] [NCBI NR]
  • gi|22946039|gb|AAN10697.1| CG4389, isoform B [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG4389 (CG4389, FBgn0028479). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:9573563..9576768. It has the cytological map location 30B12. Based on sequence similarity, it is predicted to have molecular function</span>: long-chain-3-hydroxyacyl-CoA dehydrogenase activity; long-chain-enoyl-CoA hydratase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: fatty acid beta-oxidation. 3 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • >CG4389-PC translation from_gene[CG4389 BcDNA:GH12558 FBgn0028479] seq_release:3 mol_weight=79639 cds_boundaries:(2L:9,566,002..9,568,417[-]) aa_length:744 transcript_info:[CG4389-RC seq_release:3] gene_info:[gene symbol:BcDNA:GH12558 FBgn0028479 gene_ [hmr_yeast5_DM3-1_pombe.fasta]
  • >CG4389-PB translation from_gene[CG4389 BcDNA:GH12558 FBgn0028479] seq_release:3 mol_weight=79639 cds_boundaries:(2L:9,566,002..9,568,417[-]) aa_length:744 transcript_info:[CG4389-RB seq_release:3] gene_info:[gene symbol:BcDNA:GH12558 FBgn0028479 gene_ [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q8IPE8) CG4389-PB [DrosMelano7227.FASTAC.txt]
  • CG4389-PC, isoform C [Drosophila melanogaster]gi|22946039|gb|AAN10697.1| CG4389-PB, isoform B [Drosophila melanogaster]gi|24583079|ref|NP_723471.1| CG4389-PC [Drosophila melanogaster]gi|24583077|ref|NP_723470.1| CG4389-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2L:complement(9573770..9574406,9574469..9575238,9575295..9575435,9575502..9576188); ID=FBpp0079455; name=CG4389-PC; parent=FBgn0028479,FBtr0079859; dbxref=FlyBase:FBpp0079455,FlyBase_Annotation_IDs:CG4389-PC,GB_protein:AAN10698.1,REFSEQ: [fly-100309-contam.fasta]
  • type=protein; loc=2L:complement(9573770..9574406,9574469..9575238,9575295..9575435,9575502..9576188); ID=FBpp0079453; name=CG4389-PB; parent=FBgn0028479,FBtr0079857; dbxref=FlyBase:FBpp0079453,FlyBase_Annotation_IDs:CG4389-PB,GB_protein:AAN10697.1,REFSEQ: [fly-100309-contam.fasta]
  • CG4389-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG4389-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2L:complement(9573770..9574406,9574469..9575238,9575295..9575435,9575502..9576188); ID=FBpp0079455; name=CG4389-PC; parent=FBgn0028479,FBtr0079859; dbxref=FlyBase:FBpp0079455,FlyBase_Annotation_IDs:CG4389-PC,GB_protein:AAN10698.1,REFSEQ:NP_723471,GB_protein:AAN10698; MD5=72fd0a1c9c90c8b03ffeef2549a1ca19; length=744; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:complement(9573770..9574406,9574469..9575238,9575295..9575435,9575502..9576188); ID=FBpp0079453; name=CG4389-PB; parent=FBgn0028479,FBtr0079857; dbxref=FlyBase:FBpp0079453,FlyBase_Annotation_IDs:CG4389-PB,GB_protein:AAN10697.1,REFSEQ:NP_723470,GB_protein:AAN10697; MD5=72fd0a1c9c90c8b03ffeef2549a1ca19; length=744; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:complement(9573770..9574406,9574469..9575238,9575295..9575435,9575502..9576188); ID=FBpp0079455; name=CG4389-PC; parent=FBgn0028479,FBtr0079859; dbxref=FlyBase:FBpp0079455,FlyBase_Annotation_IDs:CG4389-PC,GB_protein:AAN10698.1,REFSEQ:NP_723471,GB_protein:AAN10698; MD5=72fd0a1c9c90c8b03ffeef2549a1ca19; length=744; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=2L:complement(9573770..9574406,9574469..9575238,9575295..9575435,9575502..9576188); ID=FBpp0079453; name=CG4389-PB; parent=FBgn0028479,FBtr0079857; dbxref=FlyBase:FBpp0079453,FlyBase_Annotation_IDs:CG4389-PB,GB_protein:AAN10697.1,REFSEQ:NP_723470,GB_protein:AAN10697; MD5=72fd0a1c9c90c8b03ffeef2549a1ca19; length=744; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG4389, isoform B OS=Drosophila melanogaster GN=CG4389 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2L:complement(9573770..9574406,9574469..9575238,9575295..9575435,9575502..9576188); ID=FBpp0079455; name=Mtpalpha-PC; parent=FBgn0028479,FBtr0079859; dbxref=FlyBase:FBpp0079455,FlyBase_Annotation_IDs:CG4389-PC,GB_protein:AAN10698.1,REFSEQ:NP_723471,GB_protein:AAN10698; MD5=72fd0a1c9c90c8b03ffeef2549a1ca19; length=744; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:complement(9573770..9574406,9574469..9575238,9575295..9575435,9575502..9576188); ID=FBpp0079453; name=Mtpalpha-PB; parent=FBgn0028479,FBtr0079857; dbxref=FlyBase:FBpp0079453,FlyBase_Annotation_IDs:CG4389-PB,GB_protein:AAN10697.1,REFSEQ:NP_723470,GB_protein:AAN10697,FlyMine:FBpp0079453,modMine:FBpp0079453; MD5=72fd0a1c9c90c8b03ffeef2549a1ca19; length=744; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:complement(join(9575502..9576188,9575295..9575435,9574469..9575238,9573770..9574406)); ID=FBpp0079453; name=Mtpalpha-PB; parent=FBgn0028479,FBtr0079857; dbxref=FlyBase:FBpp0079453,FlyBase_Annotation_IDs:CG4389-PB,GB_protein:AAN10697.1,REFSEQ:NP_723470,GB_protein:AAN10697,FlyMine:FBpp0079453,modMine:FBpp0079453; MD5=72fd0a1c9c90c8b03ffeef2549a1ca19; length=744; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:complement(join(9575502..9576188,9575295..9575435,9574469..9575238,9573770..9574406)); ID=FBpp0079453; name=Mtpalpha-PB; parent=FBgn0028479,FBtr0079857; dbxref=FlyBase:FBpp0079453,FlyBase_Annotation_IDs:CG4389-PB,GB_protein:AAN10697.1,REFSEQ:NP_723470,GB_protein:AAN10697,FlyMine:FBpp0079453,modMine:FBpp0079453; MD5=72fd0a1c9c90c8b03ffeef2549a1ca19; length=744; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9V397, Mitochondrial trifunctional protein alpha subunit, isoform B OS=Drosophila melanogaster GN=Mtpalpha PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0079453 type=protein; loc=2L:complement(join(9575502..9576188,9575295..9575435,9574469..9575238,9573770..9574406)); ID=FBpp0079453; name=Mtpalpha-PB; parent=FBgn0028479,FBtr0079857; dbxref=FlyBase:FBpp0079453,FlyBase_Annotation_IDs:CG4389-PB,GB_protein:AAN10697.1,REFSEQ:NP_723470,GB_protein:AAN10697,FlyMine:FBpp0079453,modMine:FBpp0079453; MD5=72fd0a1c9c90c8b03ffeef2549a1ca19; length=744; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2L:complement(join(9575502..9576188,9575295..9575435,9574469..9575238,9573770..9574406)); ID=FBpp0079453; name=Mtpalpha-PB; parent=FBgn0028479,FBtr0079857; dbxref=FlyBase:FBpp0079453,FlyBase_Annotation_IDs:CG4389-PB,GB_protein:AAN10697.1,REFSEQ:NP_723470,GB_protein:AAN10697,UniProt/TrEMBL:Q8IPE8,FlyMine:FBpp0079453,modMine:FBpp0079453; MD5=72fd0a1c9c90c8b03ffeef2549a1ca19; length=744; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 744 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    fatty acid beta-oxidation multienzyme complex [ISS]
    Biological Process: fatty acid beta-oxidation [ISS]
    oxidation reduction [IEA]
    Molecular Function: coenzyme binding [IEA]
    3-hydroxyacyl-CoA dehydrogenase activity [IEA]
    long-chain-enoyl-CoA hydratase activity [ISS]
    long-chain-3-hydroxyacyl-CoA dehydrogenase activity [ISS]
    enoyl-CoA hydratase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTNPAPVAN KHLHTKVVNG VLVIKIDSPN AKVNSLGSEV SDEFERVIKD LETNPAVNSA  60
   61 VLISGKPGCF VAGADIGMLE ACQTAEEATL ISHGAQVMFD RMERSKKPIV AAISGVCLGG 120
  121 GLELALACHY RIATKDSKTK LGLPEVMLGL LPGGGGTVRL PKLTSVPTAL DMELTGKQVR 180
  181 ADRAKRLGIV DLLVDPLGPG LQPAEQNTIE YLEKTAVQVA NDLASGKLRV NREKSGLVSK 240
  241 IQSFVMDTDF VKNKIFDTAR KQVLKASNGL YPAPLKILDV IRAGVDKGTD AGYEAERKGF 300
  301 GELSATPESK GLIALFRGQT ECKKNRFGKP ERPVKTVGVL GAGLMGAGIV QVSVDKGYQV 360
  361 VMKDATEAGL ARGIGQVQKG LETAVKRKRI SALERDQTLA SLRPTLDYSD FKNADIIIEA 420
  421 VFEDIKVKHR VIKELEAVVP EHCVIATNTS AIPITKIAAG SSRPEKVVGM HYFSPVDKMQ 480
  481 LLEIITHPGT SKDTIAQAVA VGLKQGKVVI TVGDGPGFYT TRILSTMLSE AIRLLQEGVD 540
  541 PKDLDQYTKK FGFPVGAATL ADEVGIDVGS HIAVDLAKAF GERFSGGNLE VMNDLVLAGF 600
  601 LGRKSGKGIF LYDGQKRGTR PVNNDALEIV KQKYALVSKG ANAPEDLTLR MVSRFINEAV 660
  661 LCLEEKILDS PLEGDVGAVF GLGFPPFSGG PFRWVDQYGA GKLVSKMQSY AELYGAPFKP 720
  721 AQTLLDMAKD PSKKFYPKTG SSKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.59

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle