Protein Overview: Mcr-PA

General Information:
Name(s) found:	Mcr-PA / FBpp0079165 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7297340\|gb\|AAF52601.1\| macroglobulin complement-related [Drosophila melanogaster] [NCBI NR] gi\|17933686\|ref\|NP_524688.1\| macroglobulin complement-related [Drosophila melanogaster] [NCBI NR] gi\|16197969\|gb\|AAL13755.1\| LD23292p [Drosophila melanogaster] [NCBI NR] The gene Macroglobulin complement-related is referred to in FlyBase by the symbol Dmel\Mcr (CG7586, FBgn0020240). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:8074109..8082969. It has the cytological map location 28E1-28E3. There is experimental evidence that it has the molecular function</span>: protein binding; eukaryotic cell surface binding. There is experimental evidence that it is involved in the biological process</span>: response to yeast; phagocytosis, engulfment. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG7586-PA translation from_gene[CG7586 Mcr FBgn0020240] seq_release:3 mol_weight=202786 cds_boundaries:(2L:8,067,190..8,072,841[-]) aa_length:1760 transcript_info:[CG7586-RA seq_release:3] gene_info:[gene symbol:Mcr FBgn0020240 gene_boundaries:(2L:8,0 [hmr_yeast5_DM3-1_pombe.fasta] (Q9VLT3) CG7586 protein (LD23292P) [DrosMelano7227.FASTAC.txt] (AE003619) Mcr gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG7586-PA [Drosophila melanogaster]gi\|16197969\|gb\|AAL13755.1\| LD23292p [Drosophila melanogaster]gi\|17933686\|ref\|NP_524688.1\| CG7586-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:complement(8074956..8075167,8075254..8075359,8075428..8075602,8075663..8075856,8075920..8079667,8079763..8080610); ID=FBpp0079165; name=Mcr-PA; parent=FBgn0020240,FBtr0079543; dbxref=FlyBase:FBpp0079165,FlyBase_Annotation_IDs:CG7586-P [fly-100309-contam.fasta] Macroglobulin complement-related CG7586-PA [Drosophila melanogaster] [nr-271106-contam.fasta] CG7586-PA [Drosophila melanogaster] [nr-271106-contam.fasta] LD23292p [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2L:complement(8074956..8075167,8075254..8075359,8075428..8075602,8075663..8075856,8075920..8079667,8079763..8080610); ID=FBpp0079165; name=Mcr-PA; parent=FBgn0020240,FBtr0079543; dbxref=FlyBase:FBpp0079165,FlyBase_Annotation_IDs:CG7586-PA,GB_protein:AAF52601.1,REFSEQ:NP_524688,GB_protein:AAF52601; MD5=d3f22e6754fc0a5493c43358ccb4fdf3; length=1760; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:complement(8074956..8075167,8075254..8075359,8075428..8075602,8075663..8075856,8075920..8079667,8079763..8080610); ID=FBpp0079165; name=Mcr-PA; parent=FBgn0020240,FBtr0079543; dbxref=FlyBase:FBpp0079165,FlyBase_Annotation_IDs:CG7586-PA,GB_protein:AAF52601.1,REFSEQ:NP_524688,GB_protein:AAF52601; MD5=d3f22e6754fc0a5493c43358ccb4fdf3; length=1760; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] LD23292p OS=Drosophila melanogaster GN=Mcr PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2L:complement(8074956..8075167,8075254..8075359,8075428..8075602,8075663..8075856,8075920..8079667,8079763..8080610); ID=FBpp0079165; name=Mcr-PA; parent=FBgn0020240,FBtr0079543; dbxref=FlyBase:FBpp0079165,FlyBase_Annotation_IDs:CG7586-PA,GB_protein:AAF52601.1,REFSEQ:NP_524688,GB_protein:AAF52601,FlyMine:FBpp0079165,modMine:FBpp0079165; MD5=d3f22e6754fc0a5493c43358ccb4fdf3; length=1760; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] LD23292p OS=Drosophila melanogaster GN=Mcr PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta] type=protein; loc=2L:complement(join(8079763..8080610,8075920..8079667,8075663..8075856,8075428..8075602,8075254..8075359,8074956..8075167)); ID=FBpp0079165; name=Mcr-PA; parent=FBgn0267488,FBtr0079543; dbxref=FlyBase:FBpp0079165,FlyBase_Annotation_IDs:CG7586-PA,GB_protein:AAF52601.1,REFSEQ:NP_524688,GB_protein:AAF52601,FlyMine:FBpp0079165,modMine:FBpp0079165; MD5=d3f22e6754fc0a5493c43358ccb4fdf3; length=1760; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:complement(join(8079763..8080610,8075920..8079667,8075663..8075856,8075428..8075602,8075254..8075359,8074956..8075167)); ID=FBpp0079165; name=Mcr-PA; parent=FBgn0267488,FBtr0079543; dbxref=FlyBase:FBpp0079165,FlyBase_Annotation_IDs:CG7586-PA,GB_protein:AAF52601.1,REFSEQ:NP_524688,GB_protein:AAF52601,FlyMine:FBpp0079165,modMine:FBpp0079165; MD5=d3f22e6754fc0a5493c43358ccb4fdf3; length=1760; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0079165 type=protein; loc=2L:complement(join(8079763..8080610,8075920..8079667,8075663..8075856,8075428..8075602,8075254..8075359,8074956..8075167)); ID=FBpp0079165; name=Mcr-PA; parent=FBgn0267488,FBtr0079543; dbxref=FlyBase:FBpp0079165,FlyBase_Annotation_IDs:CG7586-PA,GB_protein:AAF52601.1,REFSEQ:NP_524688,GB_protein:AAF52601,FlyMine:FBpp0079165,modMine:FBpp0079165; MD5=d3f22e6754fc0a5493c43358ccb4fdf3; length=1760; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:complement(join(8079763..8080610,8075920..8079667,8075663..8075856,8075428..8075602,8075254..8075359,8074956..8075167)); ID=FBpp0079165; name=Mcr-PA; parent=FBgn0267488,FBtr0079543; dbxref=FlyBase:FBpp0079165,FlyBase_Annotation_IDs:CG7586-PA,GB_protein:AAF52601.1,REFSEQ:NP_524688,GB_protein:AAF52601,UniProt/TrEMBL:Q9VLT3,FlyMine:FBpp0079165,modMine:FBpp0079165; MD5=d3f22e6754fc0a5493c43358ccb4fdf3; length=1760; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1760 amino acids
Gene Ontology:
Cellular Component:	extracellular space [IEA]
Biological Process:	phagocytosis, engulfment [IMP] response to yeast [IMP]
Molecular Function:	endopeptidase inhibitor activity [ISS] protein binding [IPI] eukaryotic cell surface binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMWHLLRALL VVAAVLDALQ PAVGQNDNYY NPNQNQQNPQ QPLLPNQQWG NNPQTNQYSN  60
   61 NNQNFGQTNP SDRPPYRTDS GSYNDIAGQD DYNKRVGGGY QDNEEPSLTR GKSSYNIKAT 120
  121 FLESLHSREP TYFIVASRMV RPGLIYQVSV SILQAQYPIT VHASIACDGV QISGDSKDVK 180
  181 EGIPETLLMR IPPTSVTGSY KLRVEGFYQN VFGGLAFLNE TRLDFSQRSM TIFVQTDKPL 240
  241 YMQGETVRFR TIPITTELKG FDNPVDVYML DPNRHILKRW LSRQSNLGSV SLEYKLSDQP 300
  301 TFGEWTIRVI AQGQQEESHF TVEEYYQTRF EVNVTMPAYF FTTDPFIYGR VMANFTSGLP 360
  361 VRGNLTIKAT IRPIGYFSNQ VLNEKYRLGR SPLEQTNLYN ERWRYNNPNQ NPQVQYNVPG 420
  421 QLPQDGADLS QDILYRNQYV VERHYQFDEE WPFWVRKPEY QDSSYEAWSG TYRKTLPYLR 480
  481 YFNGTFDFKW PLRELELLVP NLANSEVLIT ATVGEKFYDE IISGYSVARV YNSSLRVVFL 540
  541 GDSPQVFKPA MPFTTYLAVE YHDGSPIDPN LLRQGLMEVS GFVESRNGGR RDWPAQRLPM 600
  601 SQQSDGIWEV KIDIRNDLNL DDRPQARDFL NGVQNMRLQA NFVDPRGERI QTELLLVSHY 660
  661 SPRNQHIKVT TSTEKPVVGE YIIFHIRTNF YLEEFNYLIM SKGVILVNDR ETITEGIKTI 720
  721 AVVLSSEMAP VATIVVWKIN QQGQVVADSL TFPVNGISRN NFTVYINNRK ARTGEKVEVA 780
  781 IFGEPGSYVG LSGIDSAFYT MQAGNELTYA KIITKMSNFD EQTNGTYKHI WYSHEGNPDE 840
  841 LVYFPASSFG VDANRTFEYS GLIVFTDGYV PRRQDTCNRT LGFGECLSGR CYRLEKQCDG 900
  901 LFDCDDGTDE INCHARNDTE LLNYRKYRFN RVLRHYENVW LWKDVNIGPH GRYIFNVEVP 960
  961 DRPAYWMVSA FSVSPSKGFG MMNKALEYVG VQPFFINVEM PEACRQGEQV GIRVTVFNYM1020
 1021 ITPIEAIVVL HDSPDYKFVH VEEDGIVRSY NPRTSFGEHQ FFIYLEAQGT TVVYVPVVPQ1080
 1081 RLGNVDVTLH VATLLGTDTI TRTLHVESDG LPQYRHQSVL LDLSNRAYVL EYMHVNVTQT1140
 1141 PEIPYQVDRY FVYGSNKARI SVVGDVVGPI FPTMPVNASS LLSLPMESGE QNAFSFAANL1200
 1201 YTIMYMRLIN QRNKTLEKNA FYHMNIGYQR QLSFMRPDGS FSLFRSDWNN SDSSVWLTSY1260
 1261 CLRVFQEASF YEWENFIWID ATIIEKNMRW LLQHQTPQGS FFEVTWLPDR KMNRTNFDKN1320
 1321 ITLTSHVLIT LATVKDISGT LGSRVALATQ RALAYIERNM DFLRHQAQPF DVAITAYALQ1380
 1381 LCNSPIAEEV FAILRRQART IGDFMYWGNQ EIPQPPRKLE NQKWFSLPRL PYEYDSLNIE1440
 1441 TTAYALLVYV ARREFFVDPI VRWLNSQRLN DGGWASTQDT SAALKALVEY TVRSRLREVS1500
 1501 SLTVEIEASS QGGKTQTLYI DDTNLAKLQS IEIPDAWGTI KVQAKGAGYA ILQMHVQYNV1560
 1561 DIEKFQTKPP VPAFGLHTKA IFHGRNQSHI SYVACQNWIN QNESERSGMA VLDVAIPTGY1620
 1621 WIQQQKLDTY VLSNRVRNLR RARYLERKIV FYFDYLDHED ICVNFTIERW YPVANMSRYL1680
 1681 PVRIYDYYAP ERFNESIFDA LPTYLLNICE VCGSSQCPYC SIYNMGWRAS MSMSLLFFSV1740
 1741 FIYLLRSRTH LVLNMMQLLT

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: Mcr-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: