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Protein Overview: Tg-PA

General Information:
Name(s) found: Tg-PA / FBpp0079155 [FlyBase]
Description(s) found:
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  • gi|33589452|gb|AAQ22493.1| RE08173p [Drosophila melanogaster] [NCBI NR]
  • gi|24582657|ref|NP_609174.1| CG7356, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|22945924|gb|AAF52590.2| CG7356, isoform A [Drosophila melanogaster] [NCBI NR]
  • The gene Transglutaminase is referred to in FlyBase by the symbol Dmel\Tg (CG7356, FBgn0031975). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:8011407..8026901. It has the cytological map location 28D3. Based on sequence similarity, it is predicted to have molecular function</span>: protein-glutamine gamma-glutamyltransferase activity. There is experimental evidence that it is involved in the biological process</span>: hemolymph coagulation. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG7356-PA translation from_gene[CG7356 CG7356 FBgn0031975] seq_release:3 mol_weight=87228 cds_boundaries:(2L:8,003,976..8,019,000[+]) aa_length:776 transcript_info:[CG7356-RA seq_release:3] gene_info:[gene symbol:CG7356 FBgn0031975 gene_boundaries:(2L [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VLU2) CG7356 protein (RE08173p) [DrosMelano7227.FASTAC.txt]
  • CG7356-PA, isoform A [Drosophila melanogaster]gi|33589452|gb|AAQ22493.1| RE08173p [Drosophila melanogaster]gi|24582657|ref|NP_609174.1| CG7356-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2L:join(8011745..8011883,8024517..8026483,8026548..8026772); ID=FBpp0079155; name=CG7356-PA; parent=FBgn0031975,FBtr0079533; dbxref=FlyBase:FBpp0079155,FlyBase_Annotation_IDs:CG7356-PA,GB_protein:AAF52590.2,REFSEQ:NP_609174,GB_protein:AA [fly-100309-contam.fasta]
  • CG7356-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • RE08173p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2L:join(8011745..8011883,8024517..8026483,8026548..8026772); ID=FBpp0079155; name=CG7356-PA; parent=FBgn0031975,FBtr0079533; dbxref=FlyBase:FBpp0079155,FlyBase_Annotation_IDs:CG7356-PA,GB_protein:AAF52590.2,REFSEQ:NP_609174,GB_protein:AAF52590; MD5=176329cadb510aafbd0eae37d3ff61b1; length=776; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:join(8011745..8011883,8024517..8026483,8026548..8026772); ID=FBpp0079155; name=CG7356-PA; parent=FBgn0031975,FBtr0079533; dbxref=FlyBase:FBpp0079155,FlyBase_Annotation_IDs:CG7356-PA,GB_protein:AAF52590.2,REFSEQ:NP_609174,GB_protein:AAF52590; MD5=176329cadb510aafbd0eae37d3ff61b1; length=776; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG7356, isoform A OS=Drosophila melanogaster GN=Tg PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2L:join(8011745..8011883,8024517..8026483,8026548..8026772); ID=FBpp0079155; name=Tg-PA; parent=FBgn0031975,FBtr0079533; dbxref=FlyBase:FBpp0079155,FlyBase_Annotation_IDs:CG7356-PA,GB_protein:AAF52590.2,REFSEQ:NP_609174,GB_protein:AAF52590,FlyMine:FBpp0079155,modMine:FBpp0079155; MD5=176329cadb510aafbd0eae37d3ff61b1; length=776; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:join(8011745..8011883,8024517..8026483,8026548..8026772); ID=FBpp0079155; name=Tg-PA; parent=FBgn0031975,FBtr0079533; dbxref=FlyBase:FBpp0079155,FlyBase_Annotation_IDs:CG7356-PA,GB_protein:AAF52590.2,REFSEQ:NP_609174,GB_protein:AAF52590,FlyMine:FBpp0079155,modMine:FBpp0079155; MD5=176329cadb510aafbd0eae37d3ff61b1; length=776; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:join(8011745..8011883,8024517..8026483,8026548..8026772); ID=FBpp0079155; name=Tg-PA; parent=FBgn0031975,FBtr0079533; dbxref=FlyBase:FBpp0079155,FlyBase_Annotation_IDs:CG7356-PA,GB_protein:AAF52590.2,REFSEQ:NP_609174,GB_protein:AAF52590,FlyMine:FBpp0079155,modMine:FBpp0079155; MD5=176329cadb510aafbd0eae37d3ff61b1; length=776; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • RE08173p OS=Drosophila melanogaster GN=Tg PE=1 SV=2 [DROME.fasta.20160308]
  • FBpp0079155 type=protein; loc=2L:join(8011745..8011883,8024517..8026483,8026548..8026772); ID=FBpp0079155; name=Tg-PA; parent=FBgn0031975,FBtr0079533; dbxref=FlyBase:FBpp0079155,FlyBase_Annotation_IDs:CG7356-PA,GB_protein:AAF52590.2,REFSEQ:NP_609174,GB_protein:AAF52590,FlyMine:FBpp0079155,modMine:FBpp0079155; MD5=176329cadb510aafbd0eae37d3ff61b1; length=776; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2L:join(8011745..8011883,8024517..8026483,8026548..8026772); ID=FBpp0079155; name=Tg-PA; parent=FBgn0031975,FBtr0079533; dbxref=FlyBase:FBpp0079155,FlyBase_Annotation_IDs:CG7356-PA,GB_protein:AAF52590.2,REFSEQ:NP_609174,GB_protein:AAF52590,UniProt/TrEMBL:Q9VLU2,FlyMine:FBpp0079155,modMine:FBpp0079155; MD5=176329cadb510aafbd0eae37d3ff61b1; length=776; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 776 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: hemolymph coagulation [IMP]
    peptide cross-linking [IEA]
    Molecular Function: protein-glutamine gamma-glutamyltransferase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGQKLSCCQK CGDWKWCTSK DNEESTLRIR NANANYFTGI PQGDKTDGAS SAVLGVLKVD  60
   61 LCLEDNHEEH HTSHFYAAAA KEALVVRRGE PFRLKIHFNR DYSPSKDAIS FIFTVADDTK 120
  121 PSPGHGTLNA LVPHDGIDYL GDTLEWGAGI ESHEGQTLTV LIKPPSTCPV TEWKLDIDTK 180
  181 LLGDGSRSYP LPLPIYVLFN PWCPDDQVYL EDRDQRKEYV MHDTTLIWRG SYNRLRPSVW 240
  241 KIGQFERHVL ECSLKVLGTV GRIPPAYRGD PVRVARALSA LVNSVDDDGV LLGNWSEDFS 300
  301 GGVAPTKWTG SVEILQQFYK TQKSVKFAQC WNFSGVLTTI ARSLGIPSRI ITCYSSAHDT 360
  361 QASLTVDVFI DANNKKLDAE TTDSIWNYHV WNELWMQRPD LGVGEHGTFD GWQVVDATPQ 420
  421 EASDNMYRVG PASVAAVKNG DILRPFDGGF VFAEVNADKL YWRYNGPSQP LKLLRKDTLA 480
  481 IGHLISTKAV LKWEREDITD TYKHAERSEE ERSTMLKALK QSRHAFSRYY LNDNFNDIEF 540
  541 DMELKDDIKI GQSFSVVLKV SNKSESRTHM ATGQISCDAV LYTGVGAVEV KTLGFELELE 600
  601 PKSSDYVRME VIFEEYYDKL SSQAAFQISA AAKVKDTDYD YYAQDDFRVR KPDIKFQLGE 660
  661 AAIVAQKELD VILRLENPLP IPLHKGVFTV EGPGIEQPLK FKIAEIPVGG TAAATFKYTP 720
  721 PYAGRGTMLA KFTSKELDDV DGYRHYEIEP RPEDLLQPNG SHRSSNIIRR RTDVIA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle