Protein Overview: TepII-PE

General Information:
Name(s) found:	TepII-PE / FBpp0079137 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|24582561\|ref\|NP_723300.1\| thiolester containing protein II, isoform E [Drosophila melanogaster] [NCBI NR] gi\|22945883\|gb\|AAN10639.1\| thiolester containing protein II, isoform E [Drosophila melanogaster] [NCBI NR] The gene Thiolester containing protein II is referred to in FlyBase by the symbol Dmel\TepII (CG7052, FBgn0041182). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:7693800..7701585. It has the cytological map location 28C1. Based on sequence similarity, it is predicted to have molecular function</span>: peptidase inhibitor activity. There is experimental evidence that it is involved in the biological process</span>: defense response to Gram-negative bacterium; antibacterial humoral response; phagocytosis, engulfment. 3 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] >CG7052-PE translation from_gene[CG7052 TepII FBgn0041182] seq_release:3 mol_weight=154278 cds_boundaries:(2L:7,686,142..7,693,652[-]) aa_length:1388 transcript_info:[CG7052-RE seq_release:3] gene_info:[gene symbol:TepII synonyms:[CG18589] FBgn0041182 [hmr_yeast5_DM3-1_pombe.fasta] (Q8IPH5) CG7052-PE [DrosMelano7227.FASTAC.txt] CG7052-PE, isoform E [Drosophila melanogaster]gi\|24582561\|ref\|NP_723300.1\| CG7052-PE [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:complement(7693908..7694996,7695073..7695971,7696028..7696206,7697977..7698094,7698725..7698992,7699055..7699316,7699379..7700668,7701360..7701421); ID=FBpp0079137; name=TepII-PE; parent=FBgn0041182,FBtr0079514; dbxref=FlyBase:FBpp007 [fly-100309-contam.fasta] Thiolester containing protein II CG7052-PE, isoform E [Drosophila melanogaster] [nr-271106-contam.fasta] CG7052-PE, isoform E [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2L:complement(7693908..7694996,7695073..7695971,7696028..7696206,7697977..7698094,7698725..7698992,7699055..7699316,7699379..7700668,7701360..7701421); ID=FBpp0079137; name=TepII-PE; parent=FBgn0041182,FBtr0079514; dbxref=FlyBase:FBpp0079137,FlyBase_Annotation_IDs:CG7052-PE,GB_protein:AAN10639.1,REFSEQ:NP_723300,GB_protein:AAN10639; MD5=1e35f270b0f294433860f9e9065a351c; length=1388; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:complement(7693908..7694996,7695073..7695971,7696028..7696206,7697977..7698094,7698725..7698992,7699055..7699316,7699379..7700668,7701360..7701421); ID=FBpp0079137; name=TepII-PE; parent=FBgn0041182,FBtr0079514; dbxref=FlyBase:FBpp0079137,FlyBase_Annotation_IDs:CG7052-PE,GB_protein:AAN10639.1,REFSEQ:NP_723300,GB_protein:AAN10639; MD5=1e35f270b0f294433860f9e9065a351c; length=1388; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Thiolester containing protein II, isoform E OS=Drosophila melanogaster GN=TepII PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2L:complement(7693908..7694996,7695073..7695971,7696028..7696206,7697977..7698094,7698725..7698992,7699055..7699316,7699379..7700668,7701360..7701421); ID=FBpp0079137; name=TepII-PE; parent=FBgn0041182,FBtr0079514; dbxref=FlyBase:FBpp0079137,FlyBase_Annotation_IDs:CG7052-PE,GB_protein:AAN10639.1,REFSEQ:NP_723300,GB_protein:AAN10639,FlyMine:FBpp0079137,modMine:FBpp0079137; MD5=1e35f270b0f294433860f9e9065a351c; length=1388; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
Organism:	Drosophila melanogaster
Length:	1388 amino acids
Gene Ontology:
Cellular Component:	extracellular space [IEA]
Biological Process:	phagocytosis, engulfment [IMP] defense response to Gram-negative bacterium [IMP] antibacterial humoral response [IDA]
Molecular Function:	peptidase inhibitor activity [ISS] protein binding [IEA] endopeptidase inhibitor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRIFLTGII LQYALLVNAT GIYSVVGPGT LRSNSKYNVV VSVHKADGPS QIKVSLNGPS  60
   61 YNETKQIELP PMSTQNVEFE VPKLATGNYN LSAEGVSGVV FKNSTKLNYA DKKPSVFVQT 120
  121 DKATYKPADL VQFRILFLDE NTRPAKIEKP ISVIIIDGAQ NRIKQLSDVK LTKGVFSGEL 180
  181 QLSEQPVLGT WKISVSVDGD NRETKSFEVD KYVLPKFEVI VDTPKAVVIA DKVIKATIRA 240
  241 KYTYGKPVKG KATVSMERSY GYFGDLNANG NKQEKTIDVD GKGHVEFDII HWAQRGQYLP 300
  301 PIKLFAVVTE ELTGNKQNAT ATVVLHQQRY SIEPYERPEH FEANKSFIYQ VVVKNVDGSP 360
  361 VTNSAKNVKI GFDKSYSYFH EPSPKTRINF EAPVNENGIA TFNVRLPDSD SRYYRIFASF 420
  421 DGSENTIGSI SKFEPTPMSR EPLKIQVNTK KPRLGEQVSF DVVSIEDLPY FVYTIVARGN 480
  481 VILSDYVDVP DGQKTYTVKF TPTFSMVPKA TIYVYYVVNN DLQFEEKTID FEKEFSNSID 540
  541 VSAPTNAKPS EEVKLRIKTD ADSFVGLLGV DQSVLLLKSG NDLSQDDIFN SLNIYQTSTP 600
  601 WMNGYGRYPG QTSGLVTLTN ANYPYNTEDS ISYDEVDAIS ITSSTKIELV RTNFAEVWMW 660
  661 TTSDNGSVGE EEFTLTKKIP DTITSWVVTG FSLNPTSGIA LTKNPSKIRV FQPFFVSTNL 720
  721 PYSVKRGEVI AIPVVIFNYL DKTLDADVVM DNSDQEYEFT EATNEVLEKA IDEVRRVKRV 780
  781 TIPANSGKSV SFMIRPKNVG FTTLKITATS ALAGDAIHQK LKVEPEGVTL FENRAVFINL 840
  841 KDQPEMSQSL DADIPNEVVP QSEFIEFSVV GDLLGPTLQN LDNLVRMPYG CGEQNMVNFV 900
  901 PNILVLKYLE VTGRKLPSVE SKARKFLEIG YQRELTYKHD DGSYSAFGKS DASGSTWLTA 960
  961 YVMRSFHQAG TYTDIDPKVI TAGLDFLVSK QKESGEFPEV GKLFDNANQN PLALTSFVLL1020
 1021 AFFENHELIP KYQSAIKKAV RYVAEEADKT DDQYSLAIAA VALQLAKHPQ SEKVIAKLES1080
 1081 VARKENDRMW WSKATESTGE DGRVFHWKPR SNDVEITSYV LLALLEKDPA EKALPIIKWL1140
 1141 ISQRNSNGGF SSTQDTVIGL QALTKFAYKT GSGSGTMDIE FSSAGESKNT IKVNPENSLV1200
 1201 LQTHDLPKST RKVDFTAKGT GSAMVQLSYR YNLAEKEKKP SFKVTPTVKD TPNQLLIVDV1260
 1261 CAEYVPLEDA DKDKDSNMAV MEIALPSGFV GDSTSLGKIQ AVDRVKRVET KNSDSTVVVY1320
 1321 FDSLTPGDVR CLPLEASKAH AVAKQKPASV SLYDYYDTER KATEYYQVKS SLCDICEGAD1380
 1381 CGEGCKKD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: TepII-PE

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: