Protein Overview: CG3523-PA

General Information:
Name(s) found:	CG3523-PA / FBpp0077343 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7295848\|gb\|AAF51148.1\| CG3523, isoform A [Drosophila melanogaster] [NCBI NR] gi\|19920632\|ref\|NP_608748.1\| CG3523, isoform A [Drosophila melanogaster] [NCBI NR] This gene is referred to in FlyBase by the symbol Dmel\CG3523 (CG3523, FBgn0027571). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:3056615..3068184. It has the cytological map location 23C5-23D1. Based on sequence similarity, it is predicted to have molecular function</span>: fatty-acid synthase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction; biosynthetic process. 14 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG3523-PA translation from_gene[CG3523 BcDNA:GH07626 FBgn0027571] seq_release:3 mol_weight=266447 cds_boundaries:(2L:3,052,477..3,060,068[+]) aa_length:2438 transcript_info:[CG3523-RA seq_release:3] gene_info:[gene symbol:BcDNA:GH07626 FBgn0027571 gen [hmr_yeast5_DM3-1_pombe.fasta] (Q9VQL7) BCDNA:GH07626 protein [DrosMelano7227.FASTAC.txt] (AE003581) BcDNA:GH07626 gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG3523-PA [Drosophila melanogaster]gi\|19920632\|ref\|NP_608748.1\| CG3523-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:join(3059908..3060142,3060230..3066957,3067020..3067115,3067184..3067327,3067389..3067502); ID=FBpp0077343; name=CG3523-PA; parent=FBgn0027571,FBtr0077659; dbxref=FlyBase:FBpp0077343,FlyBase_Annotation_IDs:CG3523-PA,GB_protein:AAF5114 [fly-100309-contam.fasta] CG3523-PA [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2L:join(3059908..3060142,3060230..3066957,3067020..3067115,3067184..3067327,3067389..3067502); ID=FBpp0077343; name=CG3523-PA; parent=FBgn0027571,FBtr0077659; dbxref=FlyBase:FBpp0077343,FlyBase_Annotation_IDs:CG3523-PA,GB_protein:AAF51148.1,REFSEQ:NP_608748,GB_protein:AAF51148; MD5=9f4009e754fc5c6e0b33d332338f2293; length=2438; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:join(3059908..3060142,3060230..3066957,3067020..3067115,3067184..3067327,3067389..3067502); ID=FBpp0077343; name=CG3523-PA; parent=FBgn0027571,FBtr0077659; dbxref=FlyBase:FBpp0077343,FlyBase_Annotation_IDs:CG3523-PA,GB_protein:AAF51148.1,REFSEQ:NP_608748,GB_protein:AAF51148; MD5=9f4009e754fc5c6e0b33d332338f2293; length=2438; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] CG3523, isoform A OS=Drosophila melanogaster GN=CG3523 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2L:join(3059908..3060142,3060230..3066957,3067020..3067115,3067184..3067327,3067389..3067502); ID=FBpp0077343; name=CG3523-PA; parent=FBgn0027571,FBtr0077659; dbxref=FlyBase:FBpp0077343,FlyBase_Annotation_IDs:CG3523-PA,GB_protein:AAF51148.1,REFSEQ:NP_608748,GB_protein:AAF51148,FlyMine:FBpp0077343,modMine:FBpp0077343; MD5=9f4009e754fc5c6e0b33d332338f2293; length=2438; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2L:join(3059908..3060142,3060230..3066957,3067020..3067115,3067184..3067327,3067389..3067502); ID=FBpp0077343; name=CG3523-PA; parent=FBgn0027571,FBtr0077659; dbxref=FlyBase:FBpp0077343,FlyBase_Annotation_IDs:CG3523-PA,GB_protein:AAF51148.1,REFSEQ:NP_608748,GB_protein:AAF51148,FlyMine:FBpp0077343,modMine:FBpp0077343; MD5=9f4009e754fc5c6e0b33d332338f2293; length=2438; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:join(3059908..3060142,3060230..3066957,3067020..3067115,3067184..3067327,3067389..3067502); ID=FBpp0077343; name=FASN1-PA; parent=FBgn0283427,FBtr0077659; dbxref=FlyBase:FBpp0077343,FlyBase_Annotation_IDs:CG3523-PA,GB_protein:AAF51148.1,REFSEQ:NP_608748,GB_protein:AAF51148,FlyMine:FBpp0077343,modMine:FBpp0077343; MD5=9f4009e754fc5c6e0b33d332338f2293; length=2438; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of B7Z001, Fatty acid synthase 1, isoform A OS=Drosophila melanogaster GN=FASN1 PE=1 SV=1 [DROME.fasta.20160308] FBpp0077343 type=protein; loc=2L:join(3059908..3060142,3060230..3066957,3067020..3067115,3067184..3067327,3067389..3067502); ID=FBpp0077343; name=FASN1-PA; parent=FBgn0283427,FBtr0077659; dbxref=FlyBase:FBpp0077343,FlyBase_Annotation_IDs:CG3523-PA,GB_protein:AAF51148.1,REFSEQ:NP_608748,GB_protein:AAF51148,FlyMine:FBpp0077343,modMine:FBpp0077343; MD5=9f4009e754fc5c6e0b33d332338f2293; length=2438; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:join(3059908..3060142,3060230..3066957,3067020..3067115,3067184..3067327,3067389..3067502); ID=FBpp0077343; name=FASN1-PA; parent=FBgn0283427,FBtr0077659; dbxref=FlyBase:FBpp0077343,FlyBase_Annotation_IDs:CG3523-PA,GB_protein:AAF51148.1,REFSEQ:NP_608748,GB_protein:AAF51148,UniProt/TrEMBL:Q9VQL7,FlyMine:FBpp0077343,modMine:FBpp0077343; MD5=9f4009e754fc5c6e0b33d332338f2293; length=2438; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	2438 amino acids
Gene Ontology:
Cellular Component:	lipid particle [IDA]
Biological Process:	oxidation reduction [IEA] biosynthetic process [IEA]
Molecular Function:	hydrolase activity, acting on ester bonds [IEA] zinc ion binding [IEA] cofactor binding [IEA] oxidoreductase activity [IEA] acyl carrier activity [IEA] fatty acid synthase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPARFAEEVI TAEPAQRAAP QLDLGGGHYV PRQQHLNDEI AITGFSGRLP ESSTIEEFKQ  60
   61 NLFDGVDMVN DDPRRWERGL YGLPDRIGKL KDSDLENFDQ QFFGVHQKQA ECMDPLLRML 120
  121 LELTHEAIID AGLNPSDLRG SRTGVYIGVS NSETEQHWCS DADRVNGYGL TGCARAMFAN 180
  181 RISFTFDFKG PSYSIDTACS SSLYALEQAF SDMREGKVDN ALVAGAGLIL KPTMSLQFKR 240
  241 LNMLSPDGSC KAFDESGNGY VRSDGCVVLL LQRTSAARRV YASILNVRTN TDGFKEQGIT 300
  301 YPIGKMQNRL IRETYEEIGL NPADVVYVEA HGTGTKVGDP QEVNSITDFF CKDRTTPLLI 360
  361 GSVKSNMGHS EPASGVCSVA KILIAMEEGV IPGNLHYNKP NPDLYGLVDG RLKVVDRNLP 420
  421 WNGGIIGLNS FGFGGANAHV ILKSNPKPKA LTPKDGALKV VLASGRTFEA VEQLLESAST 480
  481 NADDDEYLQL INEIHSKAIP NHFFRGYGVV SSKGTHQREV IESNDDKRPI WYIYSGMGSQ 540
  541 WASMAKDLMK IEAFAKTIQR CADVLKPEGV DLIDVLTRST DKSFENILNS FISIAAMQVA 600
  601 LTDLLSSLGI HPDGIVGHSV GELGCAYADG CFTPEQTVLA AYWRGKSILD TQLAKGKMAA 660
  661 VGLSWEDAHS RVPSDCFPVC HNSEDNCTIS GPEASIEALV AKLNAEGVFA KAVNSSGYAF 720
  721 HSKYIAEAGP KLRKSLEKII PNAKNRTARW ISTSIPESAW NTPVAKQSSA AYHVNNLLSP 780
  781 VLFHEALQHV PKNAISVEIA PHGLLQAILK RALGPDATNL SLVKRGHENN VEFFLTNVGK 840
  841 LFAAGAQPQV LTLVRPISYP VGRGTPMLNS KVGWDHTQKW LVAKFGKETS SGETIVEVDL 900
  901 SKEDDAFLAG HTIDGRILFP ATGYMTLAWQ TFAKMQGSEF HKTPVVMENL VFHRATILNK 960
  961 NAVVKFGINF FDGTGAFEIC ESGSLAVSGK ITIPESIDNE ELPLEEQTPS AVAKELGTND1020
 1021 VYKELRLRGY DYGGIFRGIV RSDTVASTGK LQWVDNWISF MDTMLQFSIL SKNLRELYLP1080
 1081 TRIERAVINP AKHFELLSAL TKEEQVETGL PVQWYSDINV IKSAGVELRG LKANLAQRRP1140
 1141 GTQAPPTLER YQFVPNINTT DLNENSEKAR LHALDVAIQV IIENSSGAVK LKGVELANGR1200
 1201 NPDVLVANRL LQIIEGEPVL TGDVAVVTSN NNEETITAAL GDSGVRVVSK DVLKEPVEQN1260
 1261 CHFVFGIDVL SRPDTKTLEN SIASIRENGF LILEETLPTY TKTGRALLTK FGFVAVQEQS1320
 1321 LGATRVLVLA RKAVDLKTRK SVVVVATEQN FNWVDDLKAA LATAATEEQY VYVVCQGEEL1380
 1381 FGAVGLMTCI KNENGGKLAR LVFVQDAKAE KFSLTSTLYR QQLEKDLISN VLKNGAWGTF1440
 1441 RHLKLETQQA TLQVEHAYVN ALVKGDLASL KWIEAAQADT AATVDKNLET CTVYYAPINF1500
 1501 RDVMLTSGKL AADALPGDLA EQDCVLGLEF AGRDTQGRRV MAMVPAKSLA TTCVASKRMM1560
 1561 WQIPEKWTME EASTVPCVYS TVYYALVVRG QMKKGEKILI HAGSGGVGQA AISVALAHGL1620
 1621 TVFTTVGSKE KREFLLKRFP KLQERNIGNS RDTSFEQLVL RETKGRGVDL VLNSLSEEKL1680
 1681 QASIRCLGLN GRFLEIGKFD LSNNSPLGMS VFLKNTSFHG ILLDSVMEGE EEMQNQVVSL1740
 1741 VAEGIKTGAV VPLPTSVFND QQVEQAFRFM ASGKHIGKVV IKVRDEEAGK KALQPKPRLI1800
 1801 NAIPRTYMHP EKSYILVGGL GGFGLELTNW LVTRGARYIV LTSRSGVKTG YQGLMIRRWQ1860
 1861 ERGVKVVIDT SDVTTAAGAK KLLENSNKLA LVGGIFNLAA VLRDALIEDQ TAKDFKTVAD1920
 1921 PKVTATKYLD QFSRDICTEL DYFICFSSVS CGRGNIGQTN YGLANSAMER ICEQRQVSGF1980
 1981 PGTAIQWGAI GDTGLVLENL GDNDTVIGGT LPQRMPSCLQ TIDLFLQQPH PVVASMVVAE2040
 2041 KRKSDQSAGV SLIATIANIL GLRDTKNIQD GASLADLGMD SLMSAEIKQT LERNFDIVLS2100
 2101 AQEIRQLTFG ALKAMDGGAD VKPAAAAPAA AAGVPEANIT SGGSSRTASP MGDGTQVVFT2160
 2161 TSLIPTEAIV QLDTKAPANS KQSPIFFISP IEGFASALEP LAKRLEVPAY GLQYTEAVPS2220
 2221 DSLESAAKFF IKQLRTVQPK GPYKLAGYSF GCLLTYVMAG ILEETNEVAN VIMLDGAPSY2280
 2281 VNWYTSSFKQ RYTDGTNADN DNQSYGLAYF GIVLANIDYK ALVRLLIVIP TWEEKLERFA2340
 2341 ELMSNEITQP VETIKKSATL FYKKLELADG YQPTLKLKTN VTLVKPTDNS AKLDEDYRLK2400
 2401 EVCTKPVEVH TVEGNHRTFL IEDQSLKTIQ SILKRLFN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.89

Protein Overview: CG3523-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: