Protein Overview: Rrp1-PA

General Information:
Name(s) found:	Rrp1-PA / FBpp0077362 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7295875\|gb\|AAF51175.1\| recombination repair protein 1, isoform A [Drosophila melanogaster] [NCBI NR] gi\|21428628\|gb\|AAM49974.1\| LP05366p [Drosophila melanogaster] [NCBI NR] gi\|17136678\|ref\|NP_476841.1\| recombination repair protein 1, isoform A [Drosophila melanogaster] [NCBI NR] gi\|150421656\|sp\|P27864.2\|RRP1_DROME RecName: Full=Recombination repair protein 1; AltName: Full=DNA-(apurinic or apyrimidinic site) lyase [NCBI NR] Recombination repair protein 1 OS=Drosophila melanogaster GN=Rrp1 PE=1 SV=2 [Swiss-Prot] The gene Recombination repair protein 1 is referred to in FlyBase by the symbol Dmel\Rrp1 (CG3178, FBgn0004584). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:2969773..2972676. It has the cytological map location 23C3-23C4. There is experimental evidence that it has the molecular function</span>: 3'-5' exonuclease activity; DNA-(apurinic or apyrimidinic site) lyase activity. There is experimental evidence that it is involved in the biological process</span>: cellular response to DNA damage stimulus. 9 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG3178-PA translation from_gene[CG3178 Rrp1 FBgn0004584] seq_release:3 mol_weight=74635 cds_boundaries:(2L:2,962,564..2,964,866[-]) aa_length:679 transcript_info:[CG3178-RA seq_release:3] gene_info:[gene symbol:Rrp1 FBgn0004584 gene_boundaries:(2L:2,9 [hmr_yeast5_DM3-1_pombe.fasta] (AE003581) Rrp1 gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG3178-PA [Drosophila melanogaster]gi\|21428628\|gb\|AAM49974.1\| LP05366p [Drosophila melanogaster]gi\|17136678\|ref\|NP_476841.1\| CG3178-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:complement(2969992..2970651,2970714..2970904,2970986..2971054,2971117..2971194,2971256..2972297); ID=FBpp0077362; name=Rrp1-PA; parent=FBgn0004584,FBtr0077678; dbxref=FlyBase:FBpp0077362,FlyBase_Annotation_IDs:CG3178-PA,GB_protein:AAF [fly-100309-contam.fasta] LP05366p [Drosophila melanogaster] [nr-271106-contam.fasta] Recombination repair protein 1 CG3178-PA [Drosophila melanogaster] [nr-271106-contam.fasta] CG3178-PA [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2L:complement(2969992..2970651,2970714..2970904,2970986..2971054,2971117..2971194,2971256..2972297); ID=FBpp0077362; name=Rrp1-PA; parent=FBgn0004584,FBtr0077678; dbxref=FlyBase:FBpp0077362,FlyBase_Annotation_IDs:CG3178-PA,GB_protein:AAF51175.1,REFSEQ:NP_476841,GB_protein:AAF51175; MD5=a34ef74bae2379ed43d7207c05584f5b; length=679; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:complement(2969992..2970651,2970714..2970904,2970986..2971054,2971117..2971194,2971256..2972297); ID=FBpp0077362; name=Rrp1-PA; parent=FBgn0004584,FBtr0077678; dbxref=FlyBase:FBpp0077362,FlyBase_Annotation_IDs:CG3178-PA,GB_protein:AAF51175.1,REFSEQ:NP_476841,GB_protein:AAF51175; MD5=a34ef74bae2379ed43d7207c05584f5b; length=679; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=2L:complement(2969992..2970651,2970714..2970904,2970986..2971054,2971117..2971194,2971256..2972297); ID=FBpp0077362; name=Rrp1-PA; parent=FBgn0004584,FBtr0077678; dbxref=FlyBase:FBpp0077362,FlyBase_Annotation_IDs:CG3178-PA,GB_protein:AAF51175.1,REFSEQ:NP_476841,GB_protein:AAF51175,FlyMine:FBpp0077362,modMine:FBpp0077362; MD5=a34ef74bae2379ed43d7207c05584f5b; length=679; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2L:complement(join(2971256..2972297,2971117..2971194,2970986..2971054,2970714..2970904,2969992..2970651)); ID=FBpp0077362; name=Rrp1-PA; parent=FBgn0004584,FBtr0077678; dbxref=FlyBase:FBpp0077362,FlyBase_Annotation_IDs:CG3178-PA,GB_protein:AAF51175.1,REFSEQ:NP_476841,GB_protein:AAF51175,FlyMine:FBpp0077362,modMine:FBpp0077362; MD5=a34ef74bae2379ed43d7207c05584f5b; length=679; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:complement(join(2971256..2972297,2971117..2971194,2970986..2971054,2970714..2970904,2969992..2970651)); ID=FBpp0077362; name=Rrp1-PA; parent=FBgn0004584,FBtr0077678; dbxref=FlyBase:FBpp0077362,FlyBase_Annotation_IDs:CG3178-PA,GB_protein:AAF51175.1,REFSEQ:NP_476841,GB_protein:AAF51175,FlyMine:FBpp0077362,modMine:FBpp0077362; MD5=a34ef74bae2379ed43d7207c05584f5b; length=679; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0077362 type=protein; loc=2L:complement(join(2971256..2972297,2971117..2971194,2970986..2971054,2970714..2970904,2969992..2970651)); ID=FBpp0077362; name=Rrp1-PA; parent=FBgn0004584,FBtr0077678; dbxref=FlyBase:FBpp0077362,FlyBase_Annotation_IDs:CG3178-PA,GB_protein:AAF51175.1,REFSEQ:NP_476841,GB_protein:AAF51175,FlyMine:FBpp0077362,modMine:FBpp0077362; MD5=a34ef74bae2379ed43d7207c05584f5b; length=679; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:complement(join(2971256..2972297,2971117..2971194,2970986..2971054,2970714..2970904,2969992..2970651)); ID=FBpp0077362; name=Rrp1-PA; parent=FBgn0004584,FBtr0077678; dbxref=FlyBase:FBpp0077362,FlyBase_Annotation_IDs:CG3178-PA,GB_protein:AAF51175.1,REFSEQ:NP_476841,GB_protein:AAF51175,UniProt/Swiss-Prot:P27864,FlyMine:FBpp0077362,modMine:FBpp0077362; MD5=a34ef74bae2379ed43d7207c05584f5b; length=679; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	679 amino acids
Gene Ontology:
Cellular Component:	nucleus [NAS] intracellular [IEA]
Biological Process:	DNA repair [ISS] response to DNA damage stimulus [IMP]
Molecular Function:	DNA binding [IEA] 3'-5' exonuclease activity [IDA] endonuclease activity [IEA] DNA-(apurinic or apyrimidinic site) lyase activity [IDA][ISS] double-stranded DNA specific 3'-5' exodeoxyribonuclease activity [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRVKAVKKQ AEALASEPTD PTPNANGNGV DENADSAAEE LKVPAKGKPR ARKATKTAVS  60
   61 AENSEEVEPQ KAPTAAARGK KKQPKDTDEN GQMEVVAKPK GRAKKATAEA EPEPKVDLPA 120
  121 GKATKPRAKK EPTPAPDEVT SSPPKGRAKA EKPTNAQAKG RKRKELPAEA NGGAEEAAEP 180
  181 PKQRARKEAV PTLKEQAEPG TISKEKVQKA ETAAKRARGT KRLADSEIAA ALDEPEVDEV 240
  241 PPKAASKRAK KGKMVEPSPE TVGDFQSVQE EVESPPKTAA APKKRAKKTT NGETAVELEP 300
  301 KTKAKPTKQR AKKEGKEPAP GKKQKKSADK ENGVVEEEAK PSTETKPAKG RKKAPVKAED 360
  361 VEDIEEAAEE SKPARGRKKA AAKAEEPDVD EESGSKTTKK AKKAETKTTV TLDKDAFALP 420
  421 ADKEFNLKIC SWNVAGLRAW LKKDGLQLID LEEPDIFCLQ ETKCANDQLP EEVTRLPGYH 480
  481 PYWLCMPGGY AGVAIYSKIM PIHVEYGIGN EEFDDVGRMI TAEYEKFYLI NVYVPNSGRK 540
  541 LVNLEPRMRW EKLFQAYVKK LDALKPVVIC GDMNVSHMPI DLENPKNNTK NAGFTQEERD 600
  601 KMTELLGLGF VDTFRHLYPD RKGAYTFWTY MANARARNVG WRLDYCLVSE RFVPKVVEHE 660
  661 IRSQCLGSDH CPITIFFNI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: Rrp1-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: