YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: FBpp0304020, cpb-PA

General Information:
Name(s) found: FBpp0304020 [FlyBase]
cpb-PA / FBpp0077549 [FlyBase]
Description(s) found:
Found 33 descriptions.
SHOW ALL
  • type=protein; loc=2L:join(1705278..1705280,1705400..1706227); ID=FBpp0304020; name=cpb-PB; parent=FBgn0011570,FBtr0331630; dbxref=FlyBase:FBpp0304020,FlyBase_Annotation_IDs:CG17158-PB,REFSEQ:NP_001259877,GB_protein:AGB92414; MD5=63699f7116834714c9842e71742564ae; length=276; release=r5.56; species=Dmel; [FlyBase]
  • The gene capping protein beta is referred to in FlyBase by the symbol Dmel\cpb (CG17158, FBgn0011570). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:1704904..1706962. It has the cytological map location 22B1. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. There is experimental evidence that it is involved in the biological process</span>: wing disc development; regulation of lamellipodium assembly; border follicle cell migration; actin cytoskeleton organization; regulation of actin filament length; barbed-end actin filament capping; cytoplasmic transport, nurse cell to oocyte; actin filament organization. 15 alleles are reported. The phenotypes of these alleles are annotated with: sternopleural bristle; macrochaeta; border follicle cell; nurse cell. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 276 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    F-actin capping protein complex [ISS][NAS]
    Biological Process: wing disc development [IMP]
    barbed-end actin filament capping [IDA]
    regulation of actin filament length [IMP]
    regulation of lamellipodium assembly [IMP]
    actin filament organization [IMP]
    border follicle cell migration [IMP]
    actin cytoskeleton organization [IMP]
    cytoplasmic transport, nurse cell to oocyte [IMP]
    Molecular Function: actin binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEMQMDCAL DLMRRLPPQQ IEKNLIDLID LAPDLCEDLL SSVDQPLKIA KDKEHGKDYL  60
   61 LCDYNRDGDS YRSPWSNSYY PPLEDGQMPS ERLRKLEIEA NYAFDQYREM YYEGGVSSVY 120
  121 LWDLDHGFAA VILIKKAGDG SKMIRGCWDS IHVVEVQEKT TGRTAHYKLT STAMLWLQTN 180
  181 KQGSGTMNLG GSLTRQQEQD ANVSESSPHI ANIGKMVEEM ENKIRNTLNE IYFGKTKDIV 240
  241 NGLRSTQSLA DQRQQAAMKQ DLAAAILRRN VKPESN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..276] PSI-BLAST 137.0 Capz beta-1 subunit

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • actin binding
    		•  6.56144513012007 bayes_pls_golite062009
  • actin filament binding
    		•  5.39928513902709 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  5.10504476256679 bayes_pls_golite062009
  • binding
    		•  2.46279312857752 bayes_pls_golite062009
  • protein binding
    		•  1.31870344025745 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle