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Protein Overview: Cdlc2-PA, Cdlc2-...

General Information:
Name(s) found: FBpp0294004 [FlyBase]
Cdlc2-PB / FBpp0077591 [FlyBase]
Cdlc2-PA / FBpp0077590 [FlyBase]
Description(s) found:
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  • gi|7296088|gb|AAF51383.1| cytoplasmic dynein light chain 2, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|4097199|gb|AAD00073.1| 8kd dynein light chain [NCBI NR]
  • gi|254939729|gb|ACT88127.1| AT22575p [Drosophila melanogaster] [NCBI NR]
  • gi|24580844|ref|NP_722698.1| cytoplasmic dynein light chain 2, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|22945489|gb|AAN10465.1| cytoplasmic dynein light chain 2, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|17862772|gb|AAL39863.1| LP02196p [Drosophila melanogaster] [NCBI NR]
  • gi|17137630|ref|NP_477408.1| cytoplasmic dynein light chain 2, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|14285421|sp|O96860.1|DYL2_DROME RecName: Full=Dynein light chain 2, cytoplasmic; AltName: Full=8 kDa dynein light chain [NCBI NR]
  • Dynein light chain 2, cytoplasmic OS=Drosophila melanogaster GN=Cdlc2 PE=3 SV=1 [Swiss-Prot]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0294004; name=Cdlc2-PC; parent=FBgn0026141,FBtr0305553; dbxref=REFSEQ:NP_001245836,GB_protein:AFH03513,FlyBase:FBpp0294004,FlyBase_Annotation_IDs:CG5450-PC; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r5.56; species=Dmel; [FlyBase]
  • The gene Cytoplasmic dynein light chain 2 is referred to in FlyBase by the symbol Dmel\Cdlc2 (CG5450, FBgn0026141). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:1344480..1345144. It has the cytological map location 22A1. Based on sequence similarity, it is predicted to have molecular function</span>: ATPase activity, coupled; motor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: microtubule-based movement. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG5450-PB translation from_gene[CG5450 Cdlc2 FBgn0026141] seq_release:3 mol_weight=10358 cds_boundaries:(2L:1,346,282..1,346,548[+]) aa_length:89 transcript_info:[CG5450-RB seq_release:3] gene_info:[gene symbol:Cdlc2 FBgn0026141 gene_boundaries:(2L:1, [hmr_yeast5_DM3-1_pombe.fasta]
  • >CG5450-PA translation from_gene[CG5450 Cdlc2 FBgn0026141] seq_release:3 mol_weight=10358 cds_boundaries:(2L:1,346,282..1,346,548[+]) aa_length:89 transcript_info:[CG5450-RA seq_release:3] gene_info:[gene symbol:Cdlc2 FBgn0026141 gene_boundaries:(2L:1, [hmr_yeast5_DM3-1_pombe.fasta]
  • (O96860) Dynein light chain 2, cytoplasmic (8 kDa dynein light chain) [DrosMelano7227.FASTAC.txt]
  • (AE003586) Cdlc2 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • Dlc2 [DrosMelano7227.FASTAC.txt]
  • LP02196p [Drosophila melanogaster]gi|22945489|gb|AAN10465.1| CG5450-PB, isoform B [Drosophila melanogaster]gi|7296088|gb|AAF51383.1| CG5450-PA, isoform A [Drosophila melanogaster]gi|24580844|ref|NP_722698.1| CG5450-PB [Drosophila melanogaster]gi|17137 [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0077590; name=Cdlc2-PA; parent=FBgn0026141,FBtr0077924; dbxref=FlyBase:FBpp0077590,FlyBase_Annotation_IDs:CG5450-PA,GB_protein:AAF51383.1,REFSEQ:NP_477408,GB_protein:AAF51383; MD5=8996a576bce2b5cd4a78b3375baf4 [fly-100309-contam.fasta]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0077591; name=Cdlc2-PB; parent=FBgn0026141,FBtr0077925; dbxref=FlyBase:FBpp0077591,FlyBase_Annotation_IDs:CG5450-PB,GB_protein:AAN10465.1,REFSEQ:NP_722698,GB_protein:AAN10465; MD5=8996a576bce2b5cd4a78b3375baf4 [fly-100309-contam.fasta]
  • LP02196p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Dynein light chain 2, cytoplasmic (8 kDa dynein light chain) [nr-271106-contam.fasta]
  • CG5450-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG5450-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • 8kd dynein light chain [nr-271106-contam.fasta]
  • Cytoplasmic dynein light chain 2 CG5450-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Cytoplasmic dynein light chain 2 CG5450-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0077590; name=Cdlc2-PA; parent=FBgn0026141,FBtr0077924; dbxref=FlyBase:FBpp0077590,FlyBase_Annotation_IDs:CG5450-PA,GB_protein:AAF51383.1,REFSEQ:NP_477408,GB_protein:AAF51383; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0077591; name=Cdlc2-PB; parent=FBgn0026141,FBtr0077925; dbxref=FlyBase:FBpp0077591,FlyBase_Annotation_IDs:CG5450-PB,GB_protein:AAN10465.1,REFSEQ:NP_722698,GB_protein:AAN10465; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0077590; name=Cdlc2-PA; parent=FBgn0026141,FBtr0077924; dbxref=FlyBase:FBpp0077590,FlyBase_Annotation_IDs:CG5450-PA,GB_protein:AAF51383.1,REFSEQ:NP_477408,GB_protein:AAF51383; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0077591; name=Cdlc2-PB; parent=FBgn0026141,FBtr0077925; dbxref=FlyBase:FBpp0077591,FlyBase_Annotation_IDs:CG5450-PB,GB_protein:AAN10465.1,REFSEQ:NP_722698,GB_protein:AAN10465; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Dynein light chain 2, cytoplasmic OS=Drosophila melanogaster GN=Cdlc2 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0077590; name=Cdlc2-PA; parent=FBgn0026141,FBtr0077924; dbxref=FlyBase:FBpp0077590,FlyBase_Annotation_IDs:CG5450-PA,GB_protein:AAF51383.1,REFSEQ:NP_477408,GB_protein:AAF51383,FlyMine:FBpp0077590,modMine:FBpp0077590; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0077591; name=Cdlc2-PB; parent=FBgn0026141,FBtr0077925; dbxref=FlyBase:FBpp0077591,FlyBase_Annotation_IDs:CG5450-PB,GB_protein:AAN10465.1,REFSEQ:NP_722698,GB_protein:AAN10465; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0294004; name=Cdlc2-PC; parent=FBgn0026141,FBtr0305553; dbxref=REFSEQ:NP_001245836,GB_protein:AFH03513,FlyBase:FBpp0294004,FlyBase_Annotation_IDs:CG5450-PC; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0077590; name=Cdlc2-PA; parent=FBgn0026141,FBtr0077924; dbxref=FlyBase:FBpp0077590,FlyBase_Annotation_IDs:CG5450-PA,GB_protein:AAF51383.1,REFSEQ:NP_477408,GB_protein:AAF51383,FlyMine:FBpp0077590,modMine:FBpp0077590; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0077591; name=Cdlc2-PB; parent=FBgn0026141,FBtr0077925; dbxref=FlyBase:FBpp0077591,FlyBase_Annotation_IDs:CG5450-PB,GB_protein:AAN10465.1,REFSEQ:NP_722698,GB_protein:AAN10465; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0294004; name=Cdlc2-PC; parent=FBgn0026141,FBtr0305553; dbxref=REFSEQ:NP_001245836,GB_protein:AFH03513,FlyBase:FBpp0294004,FlyBase_Annotation_IDs:CG5450-PC; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0077590; name=Cdlc2-PA; parent=FBgn0026141,FBtr0077924; dbxref=FlyBase:FBpp0077590,FlyBase_Annotation_IDs:CG5450-PA,GB_protein:AAF51383.1,REFSEQ:NP_477408,GB_protein:AAF51383,FlyMine:FBpp0077590,modMine:FBpp0077590; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0077591; name=Cdlc2-PB; parent=FBgn0026141,FBtr0077925; dbxref=FlyBase:FBpp0077591,FlyBase_Annotation_IDs:CG5450-PB,GB_protein:AAN10465.1,REFSEQ:NP_722698,GB_protein:AAN10465; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0294004; name=Cdlc2-PC; parent=FBgn0026141,FBtr0305553; dbxref=REFSEQ:NP_001245836,GB_protein:AFH03513,FlyBase:FBpp0294004,FlyBase_Annotation_IDs:CG5450-PC; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of O96860, Cytoplasmic dynein light chain 2, isoform C OS=Drosophila melanogaster GN=Cdlc2 PE=4 SV=1 [DROME.fasta.20160308]
  • FBpp0077590 type=protein; loc=2L:1344616..1344885; ID=FBpp0077590; name=Cdlc2-PA; parent=FBgn0026141,FBtr0077924; dbxref=FlyBase:FBpp0077590,FlyBase_Annotation_IDs:CG5450-PA,GB_protein:AAF51383.1,REFSEQ:NP_477408,GB_protein:AAF51383,FlyMine:FBpp0077590,modMine:FBpp0077590; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0077591 type=protein; loc=2L:1344616..1344885; ID=FBpp0077591; name=Cdlc2-PB; parent=FBgn0026141,FBtr0077925; dbxref=FlyBase:FBpp0077591,FlyBase_Annotation_IDs:CG5450-PB,GB_protein:AAN10465.1,REFSEQ:NP_722698,GB_protein:AAN10465; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0294004 type=protein; loc=2L:1344616..1344885; ID=FBpp0294004; name=Cdlc2-PC; parent=FBgn0026141,FBtr0305553; dbxref=REFSEQ:NP_001245836,GB_protein:AFH03513,FlyBase:FBpp0294004,FlyBase_Annotation_IDs:CG5450-PC; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0077590; name=Cdlc2-PA; parent=FBgn0026141,FBtr0077924; dbxref=FlyBase:FBpp0077590,FlyBase_Annotation_IDs:CG5450-PA,GB_protein:AAF51383.1,REFSEQ:NP_477408,GB_protein:AAF51383,UniProt/Swiss-Prot:O96860,FlyMine:FBpp0077590,modMine:FBpp0077590; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0077591; name=Cdlc2-PB; parent=FBgn0026141,FBtr0077925; dbxref=FlyBase:FBpp0077591,FlyBase_Annotation_IDs:CG5450-PB,GB_protein:AAN10465.1,REFSEQ:NP_722698,GB_protein:AAN10465,UniProt/Swiss-Prot:O96860; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=2L:1344616..1344885; ID=FBpp0294004; name=Cdlc2-PC; parent=FBgn0026141,FBtr0305553; dbxref=REFSEQ:NP_001245836,GB_protein:AFH03513,FlyBase:FBpp0294004,FlyBase_Annotation_IDs:CG5450-PC,UniProt/Swiss-Prot:O96860; MD5=8996a576bce2b5cd4a78b3375baf4c6e; length=89; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 89 amino acids

    Gene Ontology:
    Cellular Component: cytoplasmic dynein complex [ISS]
    cytoskeleton [NAS]
    cytoplasm [NAS]
    dynein complex [ISS]
    Biological Process: microtubule-based movement [ISS]
    microtubule-based process [IEA]
    Molecular Function: microtubule motor activity [IEA]
    motor activity [ISS]
    ATPase activity, coupled [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDRKAVIKN ADMSEEMQQD AVDCATQALE KYNIEKDIAA FIKKEFDKKY NPTWHCIVGR  60
   61 NFGSYVTHET RHFIYFYLGQ VAILLFKSG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..89] PSI-BLAST 41.0 Localisation of Dynein Light Chains 1 and 2 and their Pro-apoptotic Ligands


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle