Protein Overview: FBpp0307368, rob...

General Information:
Name(s) found:	FBpp0307368 [FlyBase] robo3-PA / FBpp0077587 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|51092123\|gb\|AAT94475.1\| LP22668p [Drosophila melanogaster] [NCBI NR] gi\|24580839\|ref\|NP_608592.2\| robo3 [Drosophila melanogaster] [NCBI NR] gi\|22945488\|gb\|AAF51387.2\| robo3 [Drosophila melanogaster] [NCBI NR] type=protein; loc=2L:join(1256891..1256945,1273585..1273778,1280599..1280701,1284606..1284890,1285304..1285444,1285506..1285637,1285745..1287049,1287161..1287259,1287501..1287741,1288133..1288293,1289455..1289728,1292648..1293686); ID=FBpp0307368; name=robo3-PB; parent=FBgn0041097,FBtr0335384; dbxref=REFSEQ:NP_001259866,GB_protein:AGB92403,FlyBase:FBpp0307368,FlyBase_Annotation_IDs:CG5423-PB; MD5=84c5265cb1f574106241a3338ad4d7fa; length=1342; release=r5.56; species=Dmel; [FlyBase] The gene robo3 is referred to in FlyBase by the symbol Dmel\robo3 (CG5423, FBgn0041097). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:1256826..1293835. It has the cytological map location 21F3-21F4. It is reported to have molecular function</span>: axon guidance receptor activity. There is experimental evidence that it is involved in the biological process</span>: axon guidance; mushroom body development; ventral cord development; neuron recognition; central complex development. 14 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: multi-cell-component structure; nervous system; embryonic nervous system; organ system; mushroom body; embryonic glial cell; embryonic neuron; multidendritic neuron; external compound sense organ; commissure; adult segment. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG5423-PA translation from_gene[CG5423 robo3 FBgn0041097] seq_release:3 mol_weight=144666 cds_boundaries:(2L:1,258,557..1,295,349[+]) aa_length:1342 transcript_info:[CG5423-RA seq_release:3] gene_info:[gene symbol:robo3 synonyms:[CG14345] FBgn0041097 [hmr_yeast5_DM3-1_pombe.fasta] (Q9VPZ7) CG5423 protein [DrosMelano7227.FASTAC.txt] CG5423-PA [Drosophila melanogaster]gi\|51092123\|gb\|AAT94475.1\| LP22668p [Drosophila melanogaster]gi\|24580839\|ref\|NP_608592.2\| CG5423-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:join(1256891..1256945,1273585..1273778,1280599..1280701,1284606..1284890,1285304..1285444,1285506..1285637,1285745..1287049,1287161..1287259,1287501..1287741,1288133..1288293,1289455..1289728,1292648..1293686); ID=FBpp0077587; name=ro [fly-100309-contam.fasta] CG5423-PA [Drosophila melanogaster] [nr-271106-contam.fasta] LP22668p [Drosophila melanogaster] [nr-271106-contam.fasta] robo3 CG5423-PA [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2L:join(1256891..1256945,1273585..1273778,1280599..1280701,1284606..1284890,1285304..1285444,1285506..1285637,1285745..1287049,1287161..1287259,1287501..1287741,1288133..1288293,1289455..1289728,1292648..1293686); ID=FBpp0077587; name=robo3-PA; parent=FBgn0041097,FBtr0077921; dbxref=FlyBase:FBpp0077587,FlyBase_Annotation_IDs:CG5423-PA,GB_protein:AAF51387.2,REFSEQ:NP_608592,GB_protein:AAF51387; MD5=84c5265cb1f574106241a3338ad4d7fa; length=1342; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:join(1256891..1256945,1273585..1273778,1280599..1280701,1284606..1284890,1285304..1285444,1285506..1285637,1285745..1287049,1287161..1287259,1287501..1287741,1288133..1288293,1289455..1289728,1292648..1293686); ID=FBpp0077587; name=robo3-PA; parent=FBgn0041097,FBtr0077921; dbxref=FlyBase:FBpp0077587,FlyBase_Annotation_IDs:CG5423-PA,GB_protein:AAF51387.2,REFSEQ:NP_608592,GB_protein:AAF51387; MD5=84c5265cb1f574106241a3338ad4d7fa; length=1342; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] LP22668p OS=Drosophila melanogaster GN=robo3 PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2L:join(1256891..1256945,1273585..1273778,1280599..1280701,1284606..1284890,1285304..1285444,1285506..1285637,1285745..1287049,1287161..1287259,1287501..1287741,1288133..1288293,1289455..1289728,1292648..1293686); ID=FBpp0077587; name=robo3-PA; parent=FBgn0041097,FBtr0077921; dbxref=FlyBase:FBpp0077587,FlyBase_Annotation_IDs:CG5423-PA,GB_protein:AAF51387.2,REFSEQ:NP_608592,GB_protein:AAF51387,FlyMine:FBpp0077587,modMine:FBpp0077587; MD5=84c5265cb1f574106241a3338ad4d7fa; length=1342; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] LP22668p OS=Drosophila melanogaster GN=robo3 PE=2 SV=2 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta] type=protein; loc=2L:join(1256891..1256945,1273585..1273778,1280599..1280701,1284606..1284890,1285304..1285444,1285506..1285637,1285745..1287049,1287161..1287259,1287501..1287741,1288133..1288293,1289455..1289728,1292648..1293686); ID=FBpp0077587; name=robo3-PA; parent=FBgn0041097,FBtr0077921; dbxref=FlyBase:FBpp0077587,FlyBase_Annotation_IDs:CG5423-PA,GB_protein:AAF51387.2,REFSEQ:NP_608592,GB_protein:AAF51387,FlyMine:FBpp0077587,modMine:FBpp0077587; MD5=84c5265cb1f574106241a3338ad4d7fa; length=1342; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:join(1256891..1256945,1273585..1273778,1280599..1280701,1284606..1284890,1285304..1285444,1285506..1285637,1285745..1287049,1287161..1287259,1287501..1287741,1288133..1288293,1289455..1289728,1292648..1293686); ID=FBpp0307368; name=robo3-PB; parent=FBgn0041097,FBtr0335384; dbxref=REFSEQ:NP_001259866,GB_protein:AGB92403,FlyBase:FBpp0307368,FlyBase_Annotation_IDs:CG5423-PB; MD5=84c5265cb1f574106241a3338ad4d7fa; length=1342; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:join(1256891..1256945,1273585..1273778,1280599..1280701,1284606..1284890,1285304..1285444,1285506..1285637,1285745..1287049,1287161..1287259,1287501..1287741,1288133..1288293,1289455..1289728,1292648..1293686); ID=FBpp0077587; name=robo3-PA; parent=FBgn0041097,FBtr0077921; dbxref=FlyBase:FBpp0077587,FlyBase_Annotation_IDs:CG5423-PA,GB_protein:AAF51387.2,REFSEQ:NP_608592,GB_protein:AAF51387,FlyMine:FBpp0077587,modMine:FBpp0077587; MD5=84c5265cb1f574106241a3338ad4d7fa; length=1342; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=2L:join(1256891..1256945,1273585..1273778,1280599..1280701,1284606..1284890,1285304..1285444,1285506..1285637,1285745..1287049,1287161..1287259,1287501..1287741,1288133..1288293,1289455..1289728,1292648..1293686); ID=FBpp0307368; name=robo3-PB; parent=FBgn0041097,FBtr0335384; dbxref=REFSEQ:NP_001259866,GB_protein:AGB92403,FlyBase:FBpp0307368,FlyBase_Annotation_IDs:CG5423-PB; MD5=84c5265cb1f574106241a3338ad4d7fa; length=1342; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0077587 type=protein; loc=2L:join(1256891..1256945,1273585..1273778,1280599..1280701,1284606..1284890,1285304..1285444,1285506..1285637,1285745..1287049,1287161..1287259,1287501..1287741,1288133..1288293,1289455..1289728,1292648..1293686); ID=FBpp0077587; name=robo3-PA; parent=FBgn0041097,FBtr0077921; dbxref=FlyBase:FBpp0077587,FlyBase_Annotation_IDs:CG5423-PA,GB_protein:AAF51387.2,REFSEQ:NP_608592,GB_protein:AAF51387,FlyMine:FBpp0077587,modMine:FBpp0077587; MD5=84c5265cb1f574106241a3338ad4d7fa; length=1342; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0307368 type=protein; loc=2L:join(1256891..1256945,1273585..1273778,1280599..1280701,1284606..1284890,1285304..1285444,1285506..1285637,1285745..1287049,1287161..1287259,1287501..1287741,1288133..1288293,1289455..1289728,1292648..1293686); ID=FBpp0307368; name=robo3-PB; parent=FBgn0041097,FBtr0335384; dbxref=REFSEQ:NP_001259866,GB_protein:AGB92403,FlyBase:FBpp0307368,FlyBase_Annotation_IDs:CG5423-PB; MD5=84c5265cb1f574106241a3338ad4d7fa; length=1342; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:join(1256891..1256945,1273585..1273778,1280599..1280701,1284606..1284890,1285304..1285444,1285506..1285637,1285745..1287049,1287161..1287259,1287501..1287741,1288133..1288293,1289455..1289728,1292648..1293686); ID=FBpp0077587; name=robo3-PA; parent=FBgn0041097,FBtr0077921; dbxref=FlyBase:FBpp0077587,FlyBase_Annotation_IDs:CG5423-PA,GB_protein:AAF51387.2,REFSEQ:NP_608592,GB_protein:AAF51387,UniProt/TrEMBL:Q9VPZ7,FlyMine:FBpp0077587,modMine:FBpp0077587; MD5=84c5265cb1f574106241a3338ad4d7fa; length=1342; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=2L:join(1256891..1256945,1273585..1273778,1280599..1280701,1284606..1284890,1285304..1285444,1285506..1285637,1285745..1287049,1287161..1287259,1287501..1287741,1288133..1288293,1289455..1289728,1292648..1293686); ID=FBpp0307368; name=robo3-PB; parent=FBgn0041097,FBtr0335384; dbxref=REFSEQ:NP_001259866,GB_protein:AGB92403,FlyBase:FBpp0307368,FlyBase_Annotation_IDs:CG5423-PB,UniProt/TrEMBL:Q9VPZ7; MD5=84c5265cb1f574106241a3338ad4d7fa; length=1342; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1342 amino acids
Gene Ontology:
Cellular Component:	plasma membrane [NAS]
Biological Process:	ventral cord development [IMP] mushroom body development [IMP] central complex development [IMP] neuron recognition [IMP] axon guidance [IMP][TAS]
Molecular Function:	axon guidance receptor activity [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDLRFVFIVF LLKWTHAQGS HPPRIVEHPI DTTVPRHEPA TLNCKAEGSP TPTIQWYKDG  60
   61 VPLKILPGSH RITLPAGGLF FLKVVNSRRE TDAGIYWCEA KNELGVARSR NATLQVAVLR 120
  121 DEFRLEPQNT RIAQGDTALL ECAAPRGIPE PTVTWKKGGQ KLDLEGSKRV RIVDGGNLAI 180
  181 QDARQTDEGQ YQCIAKNPVG VRESSLATLK VHVKPYIIRG PHDQTVLEGA SVTFPCRVGG 240
  241 DPMPDVLWLR TASGGNMPLD RVSVLEDRSL RLERVTIADE GEYSCEADNV VGAITAMGTL 300
  301 TVYAPPKFIQ RPASKSVELG ADTSFECRAI GNPKPTIFWT IKNNSTLIFP GAPPLDRFHS 360
  361 LNTEEGHSIL TLTRFQRTDK DLVILCNAMN EVASITSRVQ LSLDSQEDRP PPIIISGPVN 420
  421 QTLPIKSLAT LQCKAIGLPS PTISWYRDGI PVQPSSKLNI TTSGDLIISD LDRQQDQGLY 480
  481 TCVASSRAGK STWSGFLRIE LPTNPNIKFY RAPEQTKCPS APGQPKILNA TASALTIVWP 540
  541 TSDKAGASSF LGYSVEMYCT NQSRTWIPIA SRLSEPIFTV ESLTQGAAYM FIVRAENSLG 600
  601 FSPPSPISEP ITAGKLVGVR DGSESTGTSQ LLLSDVETLL QANDVVELLE ANASDSTTAR 660
  661 LSWDIDSGQY IEGFYLYARE LHSSEYKMVT LLNKGQGLSS CTVPGLAKAS TYEFFLVPFY 720
  721 KSIVGKPSNS RRMRTLEDVP EAPPYGMEAI QFNRTSVFLK WLPPQPNRTR NGILTSYNVV 780
  781 VKGLDVHNTT RIFKNMTIDA AAPTLLLANL TTGVTYYIAV AAATRVGVGP FSKPAVLRID 840
  841 ARTQSLDTGY TRYPISRDIA DDFLTQTWFI VLLGSIIAII VFLLGALVLF KRYQFIKQTS 900
  901 LGSLHGNHAI GTVRKFPTLP LNGGGAVGAG GSNSTAAAGQ SGHGLWIDPT SGVWRQAAGG 960
  961 GNPGGVGSCT TKEQLPGYAQ ATAQQGQQPT LLPDYERLSP LNMPDYAEVA CSTFKSPTHG1020
 1021 APPMGGGGGG QSASLYDSCG AYATTNVVAN VKLYQNRYAT KPNQSSGSNN NNHQGNDYQS1080
 1081 TGMYSAPPSA HYGCLEPKQQ QQQQQPNLMT TSTASTAILT NSPAKVKKIN ITENKMDQLE1140
 1141 GKSERTNPFN QQQQLLLASN ALKQGLGAYA NTTLAAQMAS GGGAGTLRRQ RQPKTLYKSE1200
 1201 NNILGKSGLR QNTMNASVGA PSNGQMDFLT GGPPSEGGDF SGLGLCNSTN QLLNDWASSA1260
 1261 SIAAPGDYHF GSKQPSKQHL YVKAKDGTWS AVSSDAYQSF KHQQQHHPFL AGSGDNTKSL1320
 1321 ASVNSLAGDS KFLSSFGSSA NV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: FBpp0307368, rob...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: