Protein Overview: GUC2C_RAT

General Information:
Name(s) found:	GUC2C_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6981000\|ref\|NP_037302.1\| guanylate cyclase 2C [Rattus norvegicus] [NCBI NR] gi\|548244\|gb\|AAA41201.1\| guanylyl cyclase [NCBI NR] gi\|149049152\|gb\|EDM01606.1\| rCG30304, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|1346321\|sp\|P23897.2\|GUC2C_RAT RecName: Full=Heat-stable enterotoxin receptor; Short=STA receptor; AltName: Full=Intestinal guanylate cyclase; Short=GC-C; Flags: Precursor [NCBI NR] (P23897) Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (EC 4.6.1.2) (STA receptor) [Swiss-Prot] Heat-stable enterotoxin receptor OS=Rattus norvegicus GN=Gucy2c PE=2 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):4-180359287;4-180377358;4-179900612 Heat-stable enterotoxin receptor precursor [hmr_yeast5_DM3-1_pombe.fasta] guanylate cyclase 2C; Guanylate cyclase 2C (heat stable enterotoxin receptor) [HMR_022704-rand.fasta] guanylate cyclase 2C [Rattus norvegicus]gi\|1346321\|sp\|P23897\|HSER_RAT Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (STA receptor)gi\|548244\|gb\|AAA41201.1\| guanylyl cyclase [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Heat-stable enterotoxin receptor precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_013170) guanylate cyclase 2C (heat stable enterotoxin receptor) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Heat-stable enterotoxin receptor precursor (STA receptor) (Intestinal guanylate cyclase) (GC-C) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] guanylate cyclase 2C [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG30304, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] guanylyl cyclase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 HEAT-STABLE ENTEROTOXIN RECEPTOR PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Heat-stable enterotoxin receptor precursor (GC-C) (Intestinal guanylate cyclase) (STA receptor) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Gucy2c Heat-stable enterotoxin receptor [rat-ipi-250309-contam.fasta] guanylate cyclase 2C precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Heat-stable enterotoxin receptor OS=Rattus norvegicus GN=Gucy2c [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1072 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [IEA]
Biological Process:	cGMP biosynthetic process [UNKNOWN][IEA] protein amino acid phosphorylation [IEA] response to toxin [UNKNOWN][IEA] regulation of cell proliferation [UNKNOWN][IEA]
Molecular Function:	nucleotide binding [IEA] GTP binding [IEA] toxin binding [IDA] ATP binding [IEA] protein binding [UNKNOWN][IEA] guanylate cyclase activity [UNKNOWN][IDA] protein kinase activity [IEA] receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSLLGLAVR LLLFQPTLMF WASQVRQKCH NGTYEISVLM MDNSAYKEPL QNLRDAVEEG  60
   61 LDIVRKRLRE AELNVTVNAT FIYSDGLIHK SGDCRSSTCE GLDLLREITR DRKMGCVLMG 120
  121 PSCTYSTFQM YLDTELNYPM ISAGSFGLSC DYKETLTRIL PPARKLMYFL VDFWKVNNAP 180
  181 FKTFSWNSSY VYKNGSEPED CFWYLNALEA GVSYFSEVLS FKDVLRRSEQ FQEILMGRNR 240
  241 KSNVIVMCGT PETFYNVKGD LKVADDTVVI LVDLFSNHYF EDDTRAPEYM DNVLVLTLPP 300
  301 EKFIANASVS GRFPSERSDF SLAYLEGTLL FGHMLQTFLE NGESVTTPKF ARAFRNLTFQ 360
  361 GLEGPVTLDD SGDIDNIMCL LYVSLDTRKY KVLMAYDTHK NQTIPVATSP NFIWKNHRLP 420
  421 NDVPGLGPQI LMIAVFTLTG IVVVLLLIAL LVLRKYRRDH ELRQKKWSHI PSENIFPLET 480
  481 NETNHVSLKI DDDRRRDTIQ RVRQCKYDKK KVILKDLKHC DGNFSEKQKI ELNKLLQSDY 540
  541 YNLTKFYGTV KLDTRIFGVV EYCERGSLRE VLNDTISYPD GTFMDWEFKI SVLNDIAKGM 600
  601 SYLHSSKIEV HGRLKSTNCV VDSRMVVKIT DFGCNSILPP KKDLWTAPEH LRQATISQKG 660
  661 DVYSFSIIAQ EIILRKETFY TLSCRDQNEK IFRVENSYGT KPFRPDLFLE TADEKELEVY 720
  721 LLVKSCWEED PEKRPDFKKI ESTLAKIFGL FHDQKNESYM DTLIRRLQLY SRNLEHLVEE 780
  781 RTQLYKAERD RADHLNFMLL PRLVVKSLKE KGIVEPELYE EVTIYFSDIV GFTTICKYST 840
  841 PMEVVDMLND IYKSFDQIVD HHDVYKVETI GDAYVVASGL PMRNGNRHAV DISKMALDIL 900
  901 SFMGTFELEH LPGLPVWIRI GVHSGPCAAG VVGIKMPRYC LFGDTVNTAS RMESTGLPLR 960
  961 IHMSSSTIAI LRRTDCQFLY EVRGETYLKG RGTETTYWLT GMKDQEYNLP TPPTVENQQR1020
 1021 LQTEFSDMIV SALQKRQASG VKSRRPTRVA SYKKGFLEYM QLNNSDHDST YF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: GUC2C_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: