Protein Overview: ADCY5_RAT

General Information:
Name(s) found:	ADCY5_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|2833201\|sp\|Q04400.2\|ADCY5_RAT RecName: Full=Adenylate cyclase type 5; AltName: Full=Adenylate cyclase type V; AltName: Full=ATP pyrophosphate-lyase 5; AltName: Full=Adenylyl cyclase 5 [NCBI NR] gi\|1758332\|gb\|AAB39764.1\| adenylyl cyclase type V [Rattus norvegicus] [NCBI NR] gi\|12018268\|ref\|NP_072122.1\| adenylate cyclase 5 [Rattus norvegicus] [NCBI NR] (Q04400) Adenylate cyclase, type V (EC 4.6.1.1) (ATP pyrophosphate-lyase) (Adenylyl cyclase) [Swiss-Prot] Adenylate cyclase type 5 OS=Rattus norvegicus GN=Adcy5 PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):11-21075537;11-21075537;11-21075537 Adenylate cyclase, type V [hmr_yeast5_DM3-1_pombe.fasta] adenylate cyclase 5; adenylyl cyclase type V [HMR_022704-rand.fasta] adenylate cyclase 5 [Rattus norvegicus]gi\|2833201\|sp\|Q04400\|CYA5_RAT Adenylate cyclase, type V (ATP pyrophosphate-lyase) (Adenylyl cyclase)gi\|1758332\|gb\|AAB39764.1\| adenylyl cyclase type V [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Adenylate cyclase type 5 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Adenylate cyclase type V [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_022600) adenylate cyclase 5; adenylyl cyclase type V [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Adenylate cyclase, type V [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] Adenylate cyclase type 5 (Adenylate cyclase type V) (ATP pyrophosphate-lyase 5) (Adenylyl cyclase 5) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] adenylate cyclase 5 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] adenylyl cyclase type V [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 ADENYLATE CYCLASE, TYPE V [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Adcy5 Adenylate cyclase type 5 [rat-ipi-250309-contam.fasta] Adenylate cyclase type 5 OS=Rattus norvegicus GN=Adcy5 [011711_HMR.fasta] Adenylate cyclase type 5 OS=Rattus norvegicus GN=Adcy5 PE=2 SV=2 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	1262 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] endosome [IDA] sarcolemma [IDA] membrane raft [IDA] integral to membrane [IEA] intracellular part [IDA] plasma membrane [UNKNOWN][IDA]
Biological Process:	inhibition of adenylate cyclase activity by G-protein signaling pathway [UNKNOWN] cAMP biosynthetic process [IDA] adenosine receptor signaling pathway [UNKNOWN] activation of adenylate cyclase activity by dopamine receptor signaling pathway [UNKNOWN] locomotory behavior [UNKNOWN] activation of protein kinase A activity [UNKNOWN] inhibition of adenylate cyclase activity by dopamine receptor signaling pathway [UNKNOWN] activation of adenylate cyclase activity by G-protein signaling pathway [UNKNOWN] cyclic nucleotide biosynthetic process [IEA] neuromuscular process controlling balance [UNKNOWN] hormone-mediated signaling pathway [UNKNOWN]
Molecular Function:	nucleotide binding [IEA] calcium- and calmodulin-responsive adenylate cyclase activity [IDA] ATP binding [IEA] metal ion binding [IEA] adenylate cyclase activity [UNKNOWN][IDA][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGSKSVSPP GYAAQTAASP APRGGPEHRA AWGEADSRAN GYPHAPGGST RGSTKRSGGA  60
   61 VTPQQQQRLA SRWRGGDDDE DPPLSGDDPL VGGFGFSFRS KSAWQERGGD DGGRGSRRQR 120
  121 RGAAGGGSTR APPAGGSGSS AAAAAAAGGT EVRPRSVEVG LEERRGKGRA AEELEPGTGT 180
  181 VEDGDGSEDG GSSVASGSGT GTVLSLGACC LALLQIFRSK KFPSDKLERL YQRYFFRLNQ 240
  241 SSLTMLMAVL VLVCLVMLAF HAARPPLQVV YLAVLAAAVG VILIMAVLCN RAAFHQDHMG 300
  301 LACYALIAVV LAVQVVGLLL PQPRSASEGI WWTVFFIYTI YTLLPVRMRA AVLSGVLLSA 360
  361 LHLAISLHTN AQDQFLLKQL VSNVLIFSCT NIVGVCTHYP AEVSQRQAFQ ETRECIQARL 420
  421 HSQRENQQQE RLLLSVLPRH VAMEMKADIN AKQEDMMFHK IYIQKHDNVS ILFADIEGFT 480
  481 SLASQCTAQE LVMTLNELFA RFDKLAAENH CLRIKILGDC YYCVSGLPEA RADHAHCCVE 540
  541 MGMDMIEAIS SVREVTGVNV NMRVGIHSGR VHCGVLGLRK WQFDVWSNDV TLANHMEAGG 600
  601 KAGRIHITKA TLNYLNGDYE VEPGCGGERN AYLKEHSIET FLILRCTQKR KEEKAMIAKM 660
  661 NRQRTNSIGH NPPHWGAERP FYNHLGGNQV SKEMKRMGFE DPKDKNAQES ANPEDEVDEF 720
  721 LGRAIDARSI DRLRSEHVRK FLLTFREPDL EKKYSKQVDD RFGAYVACAS LVFLFICFVQ 780
  781 ITIVPHSLFM LSFYLSCFLL LALVVFISVI YACVKLFPTP LQTLSRKIVR SKKNSTLVGV 840
  841 FTITLVFLSA FVNMFMCNSK NLVGCLAEEH NITVNQVNAC HVMESAFNYS LGDEQGFCGS 900
  901 PQSNCNFPEY FTYSVLLSLL ACSVFLQISC IGKLVLMLAI ELIYVLIVEV PGVTLFDNAD 960
  961 LLVTANAIDF SNNGTSQCPE HATKVALKVV TPIIISVFVL ALYLHAQQVE STARLDFLWK1020
 1021 LQATEEKEEM EELQAYNRRL LHNILPKDVA AHFLARERRN DELYYQSCEC VAVMFASIAN1080
 1081 FSEFYVELEA NNEGVECLRL LNEIIADFDE IISEDRFRQL EKIKTIGSTY MAASGLNDST1140
 1141 YDKAGKTHIK ALADFAMKLM DQMKYINEHS FNNFQMKIGL NIGPVVAGVI GARKPQYDIW1200
 1201 GNTVNVASRM DSTGVPDRIQ VTTDMYQVLA ANTYQLECRG VVKVKGKGEM MTYFLNGGPP1260
 1261 LS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ADCY5_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: