General Information: |
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Name(s) found: |
IL1A_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 270 amino acids |
Gene Ontology: |
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Cellular Component: |
extracellular space
[UNKNOWN][ISS]
cytosol [UNKNOWN][ISS] extracellular region [IDA] cell surface [IDA] |
Biological Process: |
negative regulation of cell proliferation
[UNKNOWN][IEA]
positive regulation of I-kappaB kinase/NF-kappaB cascade [IDA] positive regulation of mitosis [UNKNOWN][IEA] positive regulation of angiogenesis [IEA] inflammatory response [NAS] wound healing [IEP] immune response [IEA] cellular response to heat [UNKNOWN][ISS] positive regulation of cell division [IEA] cytokine-mediated signaling pathway [UNKNOWN][IEA] positive regulation of cytokine secretion [UNKNOWN][IEA] response to gamma radiation [IEP] positive regulation of steroid biosynthetic process [IDA] positive regulation vascular endothelial growth factor production [IEA] response to L-ascorbic acid [IEP] response to organic substance [IEP] response to ozone [IEP] response to copper ion [UNKNOWN][ISS] response to organic cyclic substance [IEP] fever [IEA] positive regulation of interleukin-2 biosynthetic process [UNKNOWN][IEA] positive regulation of JNK cascade [IDA] positive regulation of ERK1 and ERK2 cascade [IDA] response to lipopolysaccharide [IEP] positive regulation of interleukin-6 production [IMP] response to organic nitrogen [IEP] positive regulation of stress-activated MAPK cascade [IDA] regulation of sensory perception of pain [IDA] |
Molecular Function: |
protein binding
[UNKNOWN][IEA]
interleukin-1, Type I receptor binding [NAS] copper ion binding [UNKNOWN][ISS] cytokine activity [UNKNOWN][IMP] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MAKVPDLFED LKNCYSENEE YSSAIDHLSL NQKSFYDASY GSLHENCTDK FVSLRTSETS 60 61 KMSTFTFKES RVVVSATSNK GKILKKRRLS FNQPFTEDDL EAIAHDLEET IQPRSAPHSF 120 121 QNNLRYKLIR IVKQEFIMND SLNQNIYVDM DRIHLKAASL NDLQLEVKFD MYAYSSGGDD 180 181 SKYPVTLKVS NTQLFVSAQG EDKPVLLKEI PETPKLITGS ETDLIFFWEK INSKNYFTSA 240 241 AFPELLIATK EQSQVHLARG LPSMIDFQIS |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.99 |
Source: Reynolds et al. (2008)