Protein Overview: CP27A_RAT

General Information:
Name(s) found:	CP27A_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|O4RTV3 vitamin D3 25-monooxygenase (EC 1.14.14.-) cytochrome P450 27 precursor, mitochondrial - rat [NCBI NR] gi\|62655087\|ref\|XP_579715.1\| PREDICTED: cytochrome P450, family 27, subfamily a, polypeptide 1 [Rattus norvegicus] [NCBI NR] gi\|56034\|emb\|CAA68822.1\| vitamin D(3) 25-hydroxylase precursor [Rattus norvegicus] [NCBI NR] gi\|38511605\|gb\|AAH61848.1\| Cytochrome P450, family 27, subfamily a, polypeptide 1 [Rattus norvegicus] [NCBI NR] gi\|139949139\|ref\|NP_849178.2\| cytochrome P450, family 27, subfamily A, polypeptide 1 [Rattus norvegicus] [NCBI NR] gi\|117152\|sp\|P17178.1\|CP27A_RAT RecName: Full=Sterol 26-hydroxylase, mitochondrial; AltName: Full=Cytochrome P450 27; AltName: Full=Cytochrome P-450C27/25; AltName: Full=Sterol 27-hydroxylase; AltName: Full=Vitamin D(3) 25-hydroxylase; AltName: Full=5-bet [NCBI NR] (P17178) Cytochrome P450 27, mitochondrial precursor (EC 1.14.-.-) (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) [Swiss-Prot] Sterol 26-hydroxylase, mitochondrial OS=Rattus norvegicus GN=Cyp27a1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):9-83065367 Cytochrome P450 27, mitochondrial precursor [hmr_yeast5_DM3-1_pombe.fasta] Cytochrome P450, family 27, subfamily a, polypeptide 1 [Rattus norvegicus]gi\|56034\|emb\|CAA68822.1\| vitamin D(3) 25-hydroxylase precursor [Rattus norvegicus]gi\|117152\|sp\|P17178\|CP27_RAT Cytochrome P450 27, mitochondrial precursor (Cytochrome P-450C27/25) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Cytochrome P450 27, mitochondrial precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Cytochrome P450 27, mitochondrial precursor (Cytochrome P-450C27/25) (Sterol 26-hydroxylase) (Sterol 27-hydroxylase) (Vitamin D(3) 25-hydroxylase) (5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cytochrome P450, family 27, subfamily a, polypeptide 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Cytochrome P450, family 27, subfamily a, polypeptide 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] vitamin D(3) 25-hydroxylase precursor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 CYTOCHROME P450 27, MITOCHONDRIAL PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] cytochrome P450, family 27, subfamily A, polypeptide 1 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Cyp27a1 Cytochrome P450 27, mitochondrial [rat-ipi-250309-contam.fasta] Sterol 26-hydroxylase, mitochondrial OS=Rattus norvegicus GN=Cyp27a1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	533 amino acids
Gene Ontology:
Cellular Component:	mitochondrial matrix [UNKNOWN] mitochondrion [UNKNOWN][IDA] membrane [IEA] mitochondrial envelope [IDA] mitochondrial inner membrane [UNKNOWN][IEA]
Biological Process:	steroid catabolic process [TAS] cholesterol metabolic process [IDA] oxidation reduction [IEA]
Molecular Function:	metal ion binding [IEA] steroid hydroxylase activity [UNKNOWN] electron carrier activity [IEA] cholesterol 26-hydroxylase activity [IDA] vitamin D3 25-hydroxylase activity [IDA] cholestanetriol 26-monooxygenase activity [IEA] monooxygenase activity [IEA] heme binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVLSRMRLR WALLDTRVMG HGLCPQGARA KAAIPAALRD HESTEGPGTG QDRPRLRSLA  60
   61 ELPGPGTLRF LFQLFLRGYV LHLHELQALN KAKYGPMWTT TFGTRTNVNL ASAPLLEQVM 120
  121 RQEGKYPIRD SMEQWKEHRD HKGLSYGIFI TQGQQWYHLR HSLNQRMLKP AEAALYTDAL 180
  181 NEVISDFIAR LDQVRTESAS GDQVPDVAHL LYHLALEAIC YILFEKRVGC LEPSIPEDTA 240
  241 TFIRSVGLMF KNSVYVTFLP KWSRPLLPFW KRYMNNWDNI FSFGEKMIHQ KVQEIEAQLQ 300
  301 AAGPDGVQVS GYLHFLLTKE LLSPQETVGT FPELILAGVD TTSNTLTWAL YHLSKNPEIQ 360
  361 EALHKEVTGV VPFGKVPQNK DFAHMPLLKA VIKETLRLYP VVPTNSRIIT EKETEINGFL 420
  421 FPKNTQFVLC HYVVSRDPSV FPEPESFQPH RWLRKREDDN SGIQHPFGSV PFGYGVRSCL 480
  481 GRRIAELEMQ LLLSRLIQKY EVVLSPGMGE VKSVSRIVLV PSKKVSLRFL QRQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.52

Protein Overview: CP27A_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: