Protein Overview: EAA2_RAT

General Information:
Name(s) found:	EAA2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|417074\|sp\|P31596.2\|EAA2_RAT RecName: Full=Excitatory amino acid transporter 2; AltName: Full=Sodium-dependent glutamate/aspartate transporter 2; Short=GLUT-R; AltName: Full=GLT-1; AltName: Full=Solute carrier family 1 member 2 [NCBI NR] Excitatory amino acid transporter 2 OS=Rattus norvegicus GN=Slc1a2 PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):None Splice isoform Glt1 of P31596 [hmr_yeast5_DM3-1_pombe.fasta] L-glutamate transporter, GLT-1 [rats, brain, Peptide, 573 aa]gi\|417074\|sp\|P31596\|EAA2_RAT Excitatory amino acid transporter 2 (Sodium-dependent glutamate/aspartate transporter 2) (GLUT-R) (GLT-1) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform Glt1 of Excitatory amino acid transporter 2 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Excitatory amino acid transporter 2 (Sodium-dependent glutamate/aspartate transporter 2) (GLUT-R) (GLT-1) (Solute carrier family 1 member 2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF EXCITATORY AMINO ACID TRANSPORTER 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Excitatory amino acid transporter 2 (Sodium-dependent glutamate/aspartate transporter 2) (GLUT-R) (GLT-1) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Slc1a2 Isoform Glt1 of Excitatory amino acid transporter 2 [rat-ipi-250309-contam.fasta] Isoform Glt1 of Excitatory amino acid transporter 2 OS=Rattus norvegicus GN=Slc1a2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	573 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] presynaptic membrane [IDA] dendritic shaft [IDA] membrane [IEA] dendritic spine [IDA] integral to membrane [IEA] axolemma [UNKNOWN] synapse [IDA] neuron projection [IDA] plasma membrane [IDA] axon [UNKNOWN]
Biological Process:	multicellular organism growth [UNKNOWN] telencephalon development [UNKNOWN] L-glutamate import [UNKNOWN][IEA] nervous system development [UNKNOWN] response to wounding [UNKNOWN] response to amino acid stimulus [UNKNOWN] positive regulation of glucose import [UNKNOWN] response to light stimulus [UNKNOWN] visual behavior [UNKNOWN] dicarboxylic acid transport [IEA] neurotransmitter transport [TAS] cellular response to extracellular stimulus [UNKNOWN] response to drug [UNKNOWN] multicellular organismal aging [UNKNOWN] L-glutamate transport [UNKNOWN][IMP] D-aspartate import [UNKNOWN][IEA] adult behavior [UNKNOWN]
Molecular Function:	sodium:dicarboxylate symporter activity [IEA] symporter activity [IEA] high-affinity glutamate transmembrane transporter activity [IMP][TAS] glutamate:sodium symporter activity [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASTEGANNM PKQVEVRMHD SHLSSEEPKH RNLGMRMCDK LGKNLLLSLT VFGVILGAVC  60
   61 GGLLRLAAPI HPDVVMLIAF PGDILMRMLK MLILPLIISS LITGLSGLDA KASGRLGTRA 120
  121 MVYYMSTTII AAVLGVILVL AIHPGNPKLK KQLGPGKKND EVSSLDAFLD LIRNLFPENL 180
  181 VQACFQQIQT VTKKVLVAPP SEEANTTKAV ISLLNETMNE APEETKIVIK KGLEFKDGMN 240
  241 VLGLIGFFIA FGIAMGKMGE QAKLMVEFFN ILNEIVMKLV IMIMWYSPLG IACLICGKII 300
  301 AIKDLEVVAR QLGMYMITVI VGLIIHGGIF LPLIYFVVTR KNPFSFFAGI FQAWITALGT 360
  361 ASSAGTLPVT FRCLEDNLGI DKRVTRFVLP VGATINMDGT ALYEAVAAIF IAQMNGVILD 420
  421 GGQIVTVSLT ATLASIGAAS IPSAGLVTML LILTAVGLPT EDISLLVAVD WLLDRMRTSV 480
  481 NVVGDSFGAG IVYHLSKSEL DTIDSQHRMH EDIEMTKTQS VYDDTKNHRE SNSNQCVYAA 540
  541 HNSVVIDECK VTLAANGKSA DCSVEEEPWK REK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: EAA2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: