Protein Overview: S12A4_RAT

General Information:
Name(s) found:	S12A4_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|9507107\|ref\|NP_062102.1\| solute carrier family 12, member 4 [Rattus norvegicus] [NCBI NR] pir\|\|T31429 K-Cl cotransport protein KCC1, furosemide-sensitive - rat [NCBI NR] gi\|27151681\|sp\|Q63632.1\|S12A4_RAT RecName: Full=Solute carrier family 12 member 4; AltName: Full=Electroneutral potassium-chloride cotransporter 1; AltName: Full=Erythroid K-Cl cotransporter 1; Short=rKCC1; AltName: Full=Furosemide-sensitive K-Cl cotransp [NCBI NR] gi\|149038068\|gb\|EDL92428.1\| solute carrier family 12, member 4 [Rattus norvegicus] [NCBI NR] gi\|1403707\|gb\|AAC52634.1\| furosemide-sensitive K-Cl cotransporter [Rattus norvegicus] [NCBI NR] Solute carrier family 12 member 4 OS=Rattus norvegicus GN=Slc12a4 PE=1 SV=1 [Swiss-Prot] (Q63632) Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (rKCC1) (Furosemide-sensitive K-Cl cotransporter) [Swiss-Prot] Ensembl_locations(Chr-bp):19-33761021 Solute carrier family 12 member 4 [hmr_yeast5_DM3-1_pombe.fasta] solute carrier family 12, member 4 [HMR_022704-rand.fasta] solute carrier family 12, member 4 [Rattus norvegicus]gi\|7513994\|pir\|\|T31429 K-Cl cotransport protein KCC1, furosemide-sensitive - ratgi\|1403707\|gb\|AAC52634.1\| furosemide-sensitive K-Cl cotransportergi\|27151681\|sp\|Q63632\|S124_RAT Solute carrier family [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Solute carrier family 12 member 4 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_019229) solute carrier family 12, member 4 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Solute carrier family 12, member 4 [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (rKCC1) (Furosemide-sensitive K-Cl cotransporter) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] solute carrier family 12, member 4 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] furosemide-sensitive K-Cl cotransporter [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SOLUTE CARRIER FAMILY 12 MEMBER 4 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] solute carrier family 12 member 4 [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Solute carrier family 12 member 4 OS=Rattus norvegicus GN=Slc12a4 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1085 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [IEA]
Biological Process:	potassium ion transport [IEA] sodium ion transport [IEA] ion transport [IEA] transmembrane transport [IEA] chloride transport [IEA]
Molecular Function:	cation:chloride symporter activity [IEA] symporter activity [IEA] transporter activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPHFTVVPVD GPRRGDYDNL EGLSWVDYGE RAEREDSDGQ GNHRENSPFL SPLDASRGND  60
   61 YYDRNLALFE EELDIRPKVS SLLGKLVSYT NLTQGAKEHE EAESGEGGRR RAAKAPSMGT 120
  121 LMGVYLPCLQ NIFGVILFLR LTWMVGTAGV LQALLIVLIC CCCTLLTAIS MSAIATNGVV 180
  181 PAGGSYFMIS RSLGPEFGGA VGLCFYLGTT FAAAMYILGA IEILLTYIAP PAAIFYPSGT 240
  241 HDMSSATLNN MRVYGTIFLT FMTLVVFVGV KYVNKFASLF LACVIISILS IYVGGIKSAF 300
  301 DPPVFPVCML GNRTLSRDQF DICAKTVVVD NETVATRLWT FFCHSPNLTA DSCDPYFLLN 360
  361 NVTEIPGIPG AAAGVLQENL WSAYLEKGEV VEKHGLPSTD TLGLKESLSL YVVADIATSF 420
  421 TVLVGIFFPS VTGIMAGSNR SGDLRDAQKS IPVGTILAIV TTSLVYFSSV ILFGACIEGV 480
  481 VLRDKYGDGV SRNLVVGTLA WPSPWVIVVG SFFSTCGAGL QSLTGAPRLL QAIAKDNIIP 540
  541 FLRVFGHGKA NGEPTWALLL TALIAELGIL IASLDMVAPI LSMFFLMCYL FVNLACAVQT 600
  601 LLRTPNWRPR FKYYHWALSF LGMSLCLALM FVSSWYYALV AMVIAGMIYK YIEYQGAEKE 660
  661 WGDGIRGLSL SAARYALLRL EEGPPHTKNW RPQLLVLLKL DEDLHVKYPR LLTFASQLKA 720
  721 GKGLTIVGSV IQGSFLESYG EAQAAEQTIK NMMEIEKVKG FCQVVVASKV REGLAHLIQS 780
  781 CGLGGMRHNS VVLGWPYGWR QSEDPRAWKT FIDTVRCTTA AHLALLVPKN IAFYPSNHER 840
  841 YLEGHIDVWW IVHDGGMLML LPFLLRQHKV WKKCRMRIFT VAQMDDNSIQ MKKDLAIFLY 900
  901 HLRLEAEVEV VEMHNSDISA YTYERTLMME QRSQMLRQMR LTKTERDREA QLVKDRHSAL 960
  961 RLESLYSDEE DESVTGADKI QMTWTRDKYM AEPWDPSHAP DNFRELVHIK PDQSNVRRMH1020
 1021 TAVKLNEVIV TRSHDARLVL LNMPGPPKNS EGDENYMEFL EVLTEGLERV LLVRGGGREV1080
 1081 ITIYS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: S12A4_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: