Protein Overview: EI2BA_RAT

General Information:
Name(s) found:	EI2BA_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|623033\|gb\|AAC52196.1\| translation initiation factor eIF-2B alpha-subunit [NCBI NR] gi\|51980270\|gb\|AAH81709.1\| Eukaryotic translation initiation factor 2B, subunit 1 alpha [Rattus norvegicus] [NCBI NR] gi\|25282453\|ref\|NP_742026.1\| eukaryotic translation initiation factor 2B, subunit 1 alpha [Rattus norvegicus] [NCBI NR] gi\|2494304\|sp\|Q64270.1\|EI2BA_RAT RecName: Full=Translation initiation factor eIF-2B subunit alpha; AltName: Full=eIF-2B GDP-GTP exchange factor subunit alpha [NCBI NR] pir\|\|I59376 translation initiation factor eIF-2B alpha chain [validated] - rat [NCBI NR] gi\|149063249\|gb\|EDM13572.1\| eukaryotic translation initiation factor 2B, subunit 1 alpha [Rattus norvegicus] [NCBI NR] gi\|1096885\|prf\|\|2112359A initiation factor eIF-2B [NCBI NR] gi\|1050328\|gb\|AAA91276.1\| GTP-exchange protein [NCBI NR] Translation initiation factor eIF-2B subunit alpha OS=Rattus norvegicus GN=Eif2b1 PE=2 SV=1 [Swiss-Prot] (Q64270) Translation initiation factor eIF-2B alpha subunit (eIF-2B GDP-GTP exchange factor) [Swiss-Prot] Ensembl_locations(Chr-bp):12-34251457 Translation initiation factor eIF-2B alpha subunit [hmr_yeast5_DM3-1_pombe.fasta] translation initiation factor eIF-2B alpha-subunit [HMR_022704-rand.fasta] translation initiation factor eIF-2B alpha-subunit [Rattus norvegicus]gi\|51980270\|gb\|AAH81709.1\| Translation initiation factor eIF-2B alpha-subunit [Rattus norvegicus]gi\|2494304\|sp\|Q64270\|E2BA_RAT Translation initiation factor eIF-2B alpha subunit (eIF- [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Translation initiation factor eIF-2B alpha subunit [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Translation initiation factor eIF-2B subunit alpha (eIF-2B GDP-GTP exchange factor subunit alpha) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] eukaryotic translation initiation factor 2B, subunit 1 alpha [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Eukaryotic translation initiation factor 2B, subunit 1 alpha [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] initiation factor eIF-2B [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] GTP-exchange protein [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 TRANSLATION INITIATION FACTOR EIF-2B ALPHA SUBUNIT [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Eif2b1 Translation initiation factor eIF-2B subunit alpha [rat-ipi-250309-contam.fasta] Translation initiation factor eIF-2B subunit alpha OS=Rattus norvegicus GN=Eif2b1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	305 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [UNKNOWN][IEA] soluble fraction [IDA] cytoplasm [UNKNOWN][ISS] eukaryotic translation initiation factor 2B complex [UNKNOWN][IPI][ISS] eukaryotic translation initiation factor 2 complex [IDA][TAS] plasma membrane [UNKNOWN][IEA]
Biological Process:	regulation of translation [IMP] oligodendrocyte development [UNKNOWN][ISS] response to heat [IDA] response to glucose stimulus [IDA] cellular response to stimulus [UNKNOWN][ISS] negative regulation of translational initiation in response to stress [IMP] translational initiation [UNKNOWN][IDA][ISS] response to peptide hormone stimulus [IDA] cellular metabolic process [IEA] translation [IDA][TAS]
Molecular Function:	GTP binding [IMP] translation initiation factor activity [UNKNOWN][IDA][ISS][TAS] protein binding [UNKNOWN][IDA] guanyl-nucleotide exchange factor activity [UNKNOWN][IGI][ISS] GDP binding [IDA] enzyme regulator activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDGELIKYF KSQMKGDPNM ASAVAAIQTL LEFLKRDKGE TIQGLRAHLT KAIETLCAVD  60
   61 SSVAVSSGGE LFLRFISLTS LEYSDYSKCK KIMIERGELF LSRISLSRTK IASLCHAFIK 120
  121 DGARILTHAY SRVVLRVLEE AVAAKKRFSV YITESQPDLS GKKMAKALCH LNVPVTVVLD 180
  181 AAVGYIMEKV DLVIVGAEGV VENGGIINKI GTNQMAVCAK AQNKPFYVVA ESFKFVRLFP 240
  241 LNQQDVPDKF KYKADTLKSV QAGQDLKEEH PWVDYTSPSL ITLLFTDLGV LTPSAVSDEL 300
  301 IKLYL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.95

Protein Overview: EI2BA_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: