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Protein Overview: EI2BA_RAT

General Information:
Name(s) found: EI2BA_RAT [Swiss-Prot]
Description(s) found:
Found 22 descriptions.
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  • Translation initiation factor eIF-2B subunit alpha OS=Rattus norvegicus GN=Eif2b1 PE=2 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 305 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [UNKNOWN][IEA]
    soluble fraction [IDA]
    cytoplasm [UNKNOWN][ISS]
    eukaryotic translation initiation factor 2B complex [UNKNOWN][IPI][ISS]
    eukaryotic translation initiation factor 2 complex [IDA][TAS]
    plasma membrane [UNKNOWN][IEA]
    Biological Process: regulation of translation [IMP]
    oligodendrocyte development [UNKNOWN][ISS]
    response to heat [IDA]
    response to glucose stimulus [IDA]
    cellular response to stimulus [UNKNOWN][ISS]
    negative regulation of translational initiation in response to stress [IMP]
    translational initiation [UNKNOWN][IDA][ISS]
    response to peptide hormone stimulus [IDA]
    cellular metabolic process [IEA]
    translation [IDA][TAS]
    Molecular Function: GTP binding [IMP]
    translation initiation factor activity [UNKNOWN][IDA][ISS][TAS]
    protein binding [UNKNOWN][IDA]
    guanyl-nucleotide exchange factor activity [UNKNOWN][IGI][ISS]
    GDP binding [IDA]
    enzyme regulator activity [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDGELIKYF KSQMKGDPNM ASAVAAIQTL LEFLKRDKGE TIQGLRAHLT KAIETLCAVD  60
   61 SSVAVSSGGE LFLRFISLTS LEYSDYSKCK KIMIERGELF LSRISLSRTK IASLCHAFIK 120
  121 DGARILTHAY SRVVLRVLEE AVAAKKRFSV YITESQPDLS GKKMAKALCH LNVPVTVVLD 180
  181 AAVGYIMEKV DLVIVGAEGV VENGGIINKI GTNQMAVCAK AQNKPFYVVA ESFKFVRLFP 240
  241 LNQQDVPDKF KYKADTLKSV QAGQDLKEEH PWVDYTSPSL ITLLFTDLGV LTPSAVSDEL 300
  301 IKLYL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle