Protein Overview: GDNF_RAT

General Information:
Name(s) found:	GDNF_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|9506721\|ref\|NP_062012.1\| glial cell derived neurotrophic factor [Rattus norvegicus] [NCBI NR] gi\|729568\|sp\|Q07731.1\|GDNF_RAT RecName: Full=Glial cell line-derived neurotrophic factor; AltName: Full=Astrocyte-derived trophic factor; Short=ATF; Flags: Precursor [NCBI NR] pir\|\|A37499 glial cell line-derived neurotrophic factor precursor - rat [NCBI NR] gi\|310124\|gb\|AAA67909.1\| neurotrophic factor [Rattus norvegicus] [NCBI NR] gi\|156106248\|gb\|ABU49429.1\| glial cell line derived neurotrophic factor [Rattus norvegicus] [NCBI NR] gi\|156106246\|gb\|ABU49428.1\| glial cell line derived neurotrophic factor [Rattus norvegicus] [NCBI NR] gi\|156106242\|gb\|ABU49426.1\| glial cell line derived neurotrophic factor [Rattus norvegicus] [NCBI NR] Glial cell line-derived neurotrophic factor OS=Rattus norvegicus GN=Gdnf PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):2-50873958 Splice isoform 1 of Q07731 [hmr_yeast5_DM3-1_pombe.fasta] glial cell line derived neurotrophic factor; Glial cell line derived neutrophic factor [HMR_022704-rand.fasta] glial cell line derived neurotrophic factor [Rattus norvegicus]gi\|310124\|gb\|AAA67909.1\| neurotrophic factor [Rattus norvegicus]gi\|476785\|pir\|\|A37499 glial cell line-derived neurotrophic factor precursor - ratgi\|729568\|sp\|Q07731\|GDNF_RAT Glial cell line [nrdb_11152004_Chlamydomonas] (NM_019139) glial cell line derived neutrophic factor [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] glial cell line derived neurotrophic factor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Glial cell line-derived neurotrophic factor precursor (Astrocyte-derived trophic factor) (ATF) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] neurotrophic factor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] glial cell derived neurotrophic factor [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Glial cell line-derived neurotrophic factor precursor [nr-271106-contam.fasta] glial cell derived neurotrophic factor precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Isoform 1 of Glial cell line-derived neurotrophic factor OS=Rattus norvegicus GN=Gdnf [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	211 amino acids
Gene Ontology:
Cellular Component:	extracellular space [IDA] extracellular region [UNKNOWN]
Biological Process:	cell proliferation [IDA] neuron differentiation [IDA] neuron projection development [UNKNOWN] positive regulation of monooxygenase activity [UNKNOWN] nervous system development [UNKNOWN][TAS] response to wounding [IDA] peripheral nervous system development [UNKNOWN] regulation of morphogenesis of a branching structure [UNKNOWN] negative regulation of neuron apoptosis [UNKNOWN] positive regulation of branching involved in ureteric bud morphogenesis [UNKNOWN] mesenchymal to epithelial transition involved in metanephros morphogenesis [UNKNOWN] postsynaptic membrane organization [UNKNOWN] metanephros development [UNKNOWN] neural crest cell migration [UNKNOWN] anti-apoptosis [UNKNOWN] ureteric bud development [UNKNOWN] regulation of dopamine uptake [UNKNOWN] branching involved in ureteric bud morphogenesis [UNKNOWN] mRNA stabilization [UNKNOWN] induction of an organ [UNKNOWN] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN] peristalsis [UNKNOWN]
Molecular Function:	growth factor activity [IDA] protein homodimerization activity [UNKNOWN] glial cell line-derived neurotrophic factor receptor binding [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLWDVVAVC LVLLHTASAF PLPAGKRLLE APAEDHSLGH RRVPFALTSD SNMPEDYPDQ  60
   61 FDDVMDFIQA TIKRLKRSPD KQAAALPRRE RNRQAAAASP ENSRGKGRRG QRGKNRGCVL 120
  121 TAIHLNVTDL GLGYETKEEL IFRYCSGSCE AAETMYDKIL KNLSRSRRLT SDKVGQACCR 180
  181 PVAFDDDLSF LDDSLVYHIL RKHSAKRCGC I

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: GDNF_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: