Protein Overview: 5HT4R_RAT

General Information:
Name(s) found:	5HT4R_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|924641\|gb\|AAC52233.1\| 5-HT4L receptor [NCBI NR] gi\|6981060\|ref\|NP_036985.1\| serotonin 5-HT4 receptor [Rattus norvegicus] [NCBI NR] gi\|2494928\|sp\|Q62758.1\|5HT4R_RAT RecName: Full=5-hydroxytryptamine receptor 4; Short=5-HT-4; Short=5-HT4; AltName: Full=Serotonin receptor 4 [NCBI NR] pir\|\|S55549 serotonin 4 receptor - rat [NCBI NR] 5-hydroxytryptamine receptor 4 OS=Rattus norvegicus GN=Htr4 PE=2 SV=1 [Swiss-Prot] (Q62758) 5-hydroxytryptamine 4 receptor (5-HT-4) (Serotonin receptor 4) (5-HT4) [Swiss-Prot] Ensembl_locations(Chr-bp):18-39070853;18-39070853;18-39070853;18-39070853 Splice isoform 5-HT4L of Q62758 [hmr_yeast5_DM3-1_pombe.fasta] 5-hydroxytryptamine (serotonin) receptor 4; 5-HT4 receptor (two splicing variants L; 5-HT4 receptor (two splicing variants L and S); 5 hydroxytryptamine ( serotonin) receptor 4 [HMR_022704-rand.fasta] 5-hydroxytryptamine (serotonin) receptor 4 [Rattus norvegicus]gi\|924641\|gb\|AAC52233.1\| 5-HT4L receptorgi\|1363261\|pir\|\|S55549 serotonin 4 receptor - ratgi\|2494928\|sp\|Q62758\|5H4_RAT 5-hydroxytryptamine 4 receptor (5-HT-4) (Serotonin receptor 4) (5-HT4) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 5-HT4L of 5-hydroxytryptamine 4 receptor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012853) 5-HT4 receptor (two splicing variants L; 5-HT4 receptor (two splicing variants L and S) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] 5-hydroxytryptamine receptor 4 (5-HT-4) (5-HT4) (Serotonin receptor 4) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] serotonin 5-HT4 receptor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] 5-HT4L receptor [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF 5-HYDROXYTRYPTAMINE 4 RECEPTOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] 5-hydroxytryptamine 4 receptor (5-HT-4) (Serotonin receptor 4) (5-HT4) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Htr4 Isoform 5-HT4L of 5-hydroxytryptamine receptor 4 [rat-ipi-250309-contam.fasta] 5-hydroxytryptamine receptor 4 [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Isoform 5-HT4L of 5-hydroxytryptamine receptor 4 OS=Rattus norvegicus GN=Htr4 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	406 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [UNKNOWN] endosome [IEA] integral to membrane [IEA] plasma membrane [IEA]
Biological Process:	cognition [TAS] signal transduction [IEA] activation of adenylate cyclase activity by G-protein signaling pathway [IMP] gamma-aminobutyric acid signaling pathway [IMP]
Molecular Function:	G-protein coupled receptor activity [IEA] receptor activity [IEA] serotonin receptor activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRLDANVSS NEGFGSVEKV VLLTFFAMVI LMAILGNLLV MVAVCRDRQL RKIKTNYFIV  60
   61 SLAFADLLVS VLVNAFGAIE LVQDIWFYGE MFCLVRTSLD VLLTTASIFH LCCISLDRYY 120
  121 AICCQPLVYR NKMTPLRIAL MLGGCWVIPM FISFLPIMQG WNNIGIVDVI EKRKFNHNSN 180
  181 STFCVFMVNK PYAITCSVVA FYIPFLLMVL AYYRIYVTAK EHAQQIQMLQ RAGATSESRP 240
  241 QTADQHSTHR MRTETKAAKT LCVIMGCFCF CWAPFFVTNI VDPFIDYTVP EKVWTAFLWL 300
  301 GYINSGLNPF LYAFLNKSFR RAFLIILCCD DERYKRPPIL GQTVPCSTTT INGSTHVLRD 360
  361 TVECGGQWES RCHLTATSPL VAAQPVIRRP QDNDLEDSCS LKRSQS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: 5HT4R_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: