Protein Overview: PDE3A_RAT

General Information:
Name(s) found:	PDE3A_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8567398\|ref\|NP_059033.1\| phosphodiesterase 3A [Rattus norvegicus] [NCBI NR] gi\|3182952\|sp\|Q62865.1\|PDE3A_RAT RecName: Full=cGMP-inhibited 3',5'-cyclic phosphodiesterase A; AltName: Full=Cyclic GMP-inhibited phosphodiesterase A; Short=CGI-PDE A [NCBI NR] gi\|1145304\|gb\|AAA84964.1\| cyclic nucleotide phosphodiesterase [NCBI NR] cGMP-inhibited 3',5'-cyclic phosphodiesterase A OS=Rattus norvegicus GN=Pde3a PE=1 SV=1 [Swiss-Prot] (Q62865) cGMP-inhibited 3',5'-cyclic phosphodiesterase A (EC 3.1.4.17) (Cyclic GMP inhibited phosphodiesterase A) (CGI-PDE A) [Swiss-Prot] Ensembl_locations(Chr-bp):None cGMP-inhibited 3',5'-cyclic phosphodiesterase A [hmr_yeast5_DM3-1_pombe.fasta] cyclic nucleotide phosphodiesterase; phosphodiesterase 3A, cGMP inhibited; phosphodiesterase 3A cGMP inhibited [HMR_022704-rand.fasta] cyclic nucleotide phosphodiesterase [Rattus norvegicus]gi\|1145304\|gb\|AAA84964.1\| cyclic nucleotide phosphodiesterasegi\|3182952\|sp\|Q62865\|CN3A_RAT cGMP-inhibited 3',5'-cyclic phosphodiesterase A (Cyclic GMP inhibited phosphodiesterase A) (CGI-PDE A) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_017337) cyclic nucleotide phosphodiesterase; phosphodiesterase 3A, cGMP inhibited [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] cGMP-inhibited 3',5'-cyclic phosphodiesterase A (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] phosphodiesterase 3A, cGMP inhibited [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cyclic nucleotide phosphodiesterase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 CGMP-INHIBITED 3',5'-CYCLIC PHOSPHODIESTERASE A [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] cyclic nucleotide phosphodiesterase [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Pde3a cGMP-inhibited 3',5'-cyclic phosphodiesterase A [rat-ipi-250309-contam.fasta] cGMP-inhibited 3',5'-cyclic phosphodiesterase A OS=Rattus norvegicus GN=Pde3a [011711_HMR.fasta] cGMP-inhibited 3',5'-cyclic phosphodiesterase A OS=Rattus norvegicus GN=Pde3a PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	1141 amino acids
Gene Ontology:
Cellular Component:	insoluble fraction [UNKNOWN][IEA] soluble fraction [UNKNOWN][IDA] membrane [IEA] integral to membrane [IEA] cytosol [IDA]
Biological Process:	oocyte maturation [UNKNOWN][IEP][TAS] signal transduction [IEA] response to drug [UNKNOWN][IEA] negative regulation of apoptosis [IMP] regulation of meiosis [UNKNOWN][IEA] response to cAMP [IEP] cAMP catabolic process [IDA]
Molecular Function:	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity [IDA] metal ion binding [IEA] cAMP binding [IDA] cyclic-nucleotide phosphodiesterase activity [TAS] 3',5'-cyclic-AMP phosphodiesterase activity [UNKNOWN][IDA] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVRGEAAQD WAKPGLRGPS PAPVARGDHR CRGGSPSSPR GSGCCWRALA LQPLRRSPQL  60
   61 SSALCAGSLS VLLALLVRLV GGEVGGELES SQEAAAEEEE EEGARGGVFP GPRGGAPGGG 120
  121 AQLSPWLQPA ALLFSLLCAF FWMGLCLLRA GVRLPLAVAL LAACCAGEAL VQLSLGVGDG 180
  181 RLLSLPAAGV LLSCLGGATW LVLRLRLGVL MVALTSALRT VALVSLERFK VAWRPYLAYL 240
  241 AAVLGLLLAR YAEQLLPQCS GPAPPRERFG SQSSARTKEE IPGWKRRRRS SSVVAGEMSG 300
  301 CGGKSHRRTS LPCIPREQLM GHSEWDHKRG SRGSQSGTSV TVDIAVMGEA HGLITDLLAD 360
  361 PSLPPNVCTS LRAVSNLLST QLTFQAIHKP RVNPTVTFSE NYTCSDSEEG LEKDKLAIPK 420
  421 RLRRSLPPGL LRRVSSTWTT TTSATGLPTL EPAPVRRDRS ASIKPHEAPS PSAVNPDSWN 480
  481 APVLMTLTKS RSFTSSYAVS AANHVKAKKQ NRPGGLDKIS PVPSPSSSPP QGSPTSSPVS 540
  541 GIASVQFPES PEVTTKRGPG SHRALTYTQS APDLSPQIPP SPVICSSCGR PYSQGNPADG 600
  601 PSERSGPAMQ KPNRTDDTSQ VTSDYETNNN SDSSDILQND EEAECQREPL RKASACGTYT 660
  661 PQTMIFLDKP ILAPEPLVMD NLDSIMDQLN TWNFPIFDLV ENIGRKCGRI LSQVSYRLFE 720
  721 DMGLFEAFKI PVREFMNYFH ALEIGYRDIP YHNRIHATDV LHAVWYLTTQ PIPGLPSVIG 780
  781 DHGSASDSDS DSGFTHGHMG YVFSKAYHVP DDKYGCLSGN IPALELMALY VAAAMHDYDH 840
  841 PGRTNAFLVA TSAPQAVLYN DRSVLENHHA AAAWNLFMSR PEYNFLVNLD HVEFKHFRFL 900
  901 VIEAILATDL KKHFDFVAKF NAKVNDDVGI DWTNENDRLL VCQMCIKLAD INGPAKCKDL 960
  961 HLRWTEGIAS EFYEQGDEEA SLGLPISPFM DRSAPQLANL QESFISHIVG PLCHSYDSAG1020
 1021 LMPGKWVDDS DDSGDTDDPE EEEEEAETPH EEETCENSEA PRKKSFKRRR IYCQITQHLL1080
 1081 QNHMMWKKVI EEEQCLSGTE NQAPDQAPLQ HSSEQIQAIK EEEEEKGKPR AEETLAPQPD1140
 1141 L

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: PDE3A_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: