Protein Overview: DLG4_RAT

General Information:
Name(s) found:	DLG4_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|9665227\|ref\|NP_062567.1\| post-synaptic density protein 95 [Rattus norvegicus] [NCBI NR] gi\|400891\|sp\|P31016.1\|DLG4_RAT RecName: Full=Disks large homolog 4; AltName: Full=Postsynaptic density protein 95; Short=PSD-95; AltName: Full=Synapse-associated protein 90; Short=SAP90 [NCBI NR] pir\|\|JH0800 postsynaptic density protein PSD-95 - rat [NCBI NR] gi\|206455\|gb\|AAA41971.1\| postsynaptic density protein [NCBI NR] Disks large homolog 4 OS=Rattus norvegicus GN=Dlg4 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):10-54423931;10-54423931;10-54423931 Presynaptic density protein 95 [hmr_yeast5_DM3-1_pombe.fasta] postsynaptic density protein 95; synapse-associated protein SAP90; discs large homolog 4; discs large homolog 4 (Drosophila) [HMR_022704-rand.fasta] postsynaptic density protein 95 [Rattus norvegicus]gi\|346986\|pir\|\|JH0800 postsynaptic density protein PSD-95 - ratgi\|206455\|gb\|AAA41971.1\| postsynaptic density proteingi\|400891\|sp\|P31016\|DLG4_RAT Presynaptic density protein 95 (PSD-95) (Presynaptic pro [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Discs large homolog 4 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Splice Isoform 1 of Postsynaptic density protein 95 [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_019621) discs, large homolog 4; synapse-associated protein SAP90 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Presynaptic density protein 95 [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] post-synaptic density protein 95 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] postsynaptic density protein [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 PRESYNAPTIC DENSITY PROTEIN 95 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Discs large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP90) [nr-271106-contam.fasta] postsynaptic density protein 95 [Rattus norvegicus] [nr-271106-contam.fasta] Isoform 1 of Disks large homolog 4 OS=Rattus norvegicus GN=Dlg4 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	724 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [UNKNOWN] alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [UNKNOWN][IEA] postsynaptic density [UNKNOWN][IDA] synaptosome [UNKNOWN][IDA] cytoplasm [UNKNOWN][IEA] postsynaptic membrane [UNKNOWN][IDA] cell junction [IEA] extrinsic to internal side of plasma membrane [UNKNOWN][IEA] synapse [UNKNOWN][IDA] plasma membrane [UNKNOWN][IEA] endocytic vesicle membrane [UNKNOWN] cortical cytoskeleton [UNKNOWN]
Biological Process:	neuronal ion channel clustering [TAS] regulation of long-term neuronal synaptic plasticity [UNKNOWN][IEA] synaptic vesicle maturation [UNKNOWN][IEA] response to stress [NAS]
Molecular Function:	ionotropic glutamate receptor binding [IPI] protein binding [UNKNOWN][IDA][IEA][IPI] protein C-terminus binding [UNKNOWN][IPI] PDZ domain binding [IPI] receptor binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDCLCIVTTK KYRYQDEDTP PLEHSPAHLP NQANSPPVIV NTDTLEAPGY ELQVNGTEGE  60
   61 MEYEEITLER GNSGLGFSIA GGTDNPHIGD DPSIFITKII PGGAAAQDGR LRVNDSILFV 120
  121 NEVDVREVTH SAAVEALKEA GSIVRLYVMR RKPPAEKVME IKLIKGPKGL GFSIAGGVGN 180
  181 QHIPGDNSIY VTKIIEGGAA HKDGRLQIGD KILAVNSVGL EDVMHEDAVA ALKNTYDVVY 240
  241 LKVAKPSNAY LSDSYAPPDI TTSYSQHLDN EISHSSYLGT DYPTAMTPTS PRRYSPVAKD 300
  301 LLGEEDIPRE PRRIVIHRGS TGLGFNIVGG EDGEGIFISF ILAGGPADLS GELRKGDQIL 360
  361 SVNGVDLRNA SHEQAAIALK NAGQTVTIIA QYKPEEYSRF EAKIHDLREQ LMNSSLGSGT 420
  421 ASLRSNPKRG FYIRALFDYD KTKDCGFLSQ ALSFRFGDVL HVIDAGDEEW WQARRVHSDS 480
  481 ETDDIGFIPS KRRVERREWS RLKAKDWGSS SGSQGREDSV LSYETVTQME VHYARPIIIL 540
  541 GPTKDRANDD LLSEFPDKFG SCVPHTTRPK REYEIDGRDY HFVSSREKME KDIQAHKFIE 600
  601 AGQYNSHLYG TSVQSVREVA EQGKHCILDV SANAVRRLQA AHLHPIAIFI RPRSLENVLE 660
  661 INKRITEEQA RKAFDRATKL EQEFTECFSA IVEGDSFEEI YHKVKRVIED LSGPYIWVPA 720
  721 RERL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: DLG4_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: