Protein Overview: SMAD5_RAT

General Information:
Name(s) found:	SMAD5_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|5706366\|dbj\|BAA83093.1\| Smad5 [Rattus norvegicus] [NCBI NR] gi\|171846568\|gb\|AAI61849.1\| SMAD family member 5 [Rattus norvegicus] [NCBI NR] gi\|13959533\|sp\|Q9R1V3.1\|SMAD5_RAT RecName: Full=Mothers against decapentaplegic homolog 5; Short=Mothers against DPP homolog 5; AltName: Full=SMAD 5; Short=Smad5 [NCBI NR] gi\|11067423\|ref\|NP_067724.1\| SMAD family member 5 [Rattus norvegicus] [NCBI NR] Mothers against decapentaplegic homolog 5 OS=Rattus norvegicus GN=Smad5 PE=1 SV=1 [Swiss-Prot] (Q9R1V3) Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) [Swiss-Prot] Ensembl_locations(Chr-bp):17-16533454;17-16601554 Mothers against decapentaplegic homolog 5 [hmr_yeast5_DM3-1_pombe.fasta] Smad5 [HMR_022704-rand.fasta] Smad5 [Rattus norvegicus]gi\|13959533\|sp\|Q9R1V3\|SMA5_RAT Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5)gi\|5706366\|dbj\|BAA83093.1\| Smad5 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Mothers against decapentaplegic homolog 5 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_021692) Smad5 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Mothers against decapentaplegic homolog 5 (Mothers against DPP homolog 5) (SMAD 5) (Smad5) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] MAD homolog 5 (Drosophila) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] SMAD, mothers against DPP homolog 5 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Smad5 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG 5 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] SMAD family member 5 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Mothers against decapentaplegic homolog 5 (SMAD 5) (Mothers against DPP homolog 5) (Smad5) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Smad5 Mothers against decapentaplegic homolog 5 [rat-ipi-250309-contam.fasta] Mothers against decapentaplegic homolog 5 OS=Rattus norvegicus GN=Smad5 [011711_HMR.fasta] Mothers against decapentaplegic homolog 5 OS=Rattus norvegicus GN=Smad5 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta] SMAD family member 5 OS=Rattus norvegicus GN=Smad5 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta] Isoform of Q9R1V3, Mothers against decapentaplegic homolog OS=Rattus norvegicus GN=Smad5 PE=1 SV=1 [RAT.fasta.20160308]
Organism:	Rattus norvegicus
Length:	465 amino acids
Gene Ontology:
Cellular Component:	nucleus [IEA] transcription factor complex [IEA] cytosol [UNKNOWN] intracellular [IEA] nucleoplasm [UNKNOWN]
Biological Process:	germ cell development [UNKNOWN][IEA] osteoblast fate commitment [UNKNOWN][IEA] transforming growth factor beta receptor signaling pathway [UNKNOWN][IEA] regulation of transcription, DNA-dependent [IEA] protein amino acid phosphorylation [UNKNOWN] positive regulation of osteoblast differentiation [UNKNOWN][IEA] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN][IEA] cardiac muscle contraction [UNKNOWN][IEA] Mullerian duct regression [IMP] erythrocyte differentiation [UNKNOWN][IEA] ossification [IEP] ureteric bud development [UNKNOWN][IEA] BMP signaling pathway [UNKNOWN] regulation of ossification [NAS]
Molecular Function:	transcription factor activity [IEA] protein binding [UNKNOWN][IEA] ubiquitin protein ligase binding [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSMASLFSF TSPAVKRLLG WKQGDEEEKW AEKAVDALVK KLKKKKGAME ELEKALSSPG  60
   61 QPSKCVTIPR SLDGRLQVSH RKGLPHVIYC RVWRWPDLQS HHELKPLDIC EFPFGSKQKE 120
  121 VCINPYHYKR VESPVLPPVL VPRHNEFNPQ HSLLVQFRNL SHNEPHMPQN ATFPDSFHQP 180
  181 NSTPFPLSPN SPYPPSPASS TYPNSPASSG PGSPFQLPAD TPPPAYMPPD DQMGQDNSQP 240
  241 MDTSNNMIPQ IMPSISSRDV QPVAYEEPKH WCSIVYYELN NRVGEAFHAS STSVLVDGFT 300
  301 DPANNKSRFC LGLLSNVNRN STIENTRRHI GKGVHLYYVG GEVYAECLSD SSIFVQSRNC 360
  361 NFHHGFHPTT VCKIPSSCSL KIFNNQEFAQ LLAQSVNHGF EAVYELTKMC TIRMSFVKGW 420
  421 GAEYHRQDVT STPCWIEIHL HGPLQWLDKV LTQMGSPLNP ISSVS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: SMAD5_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: