Protein Overview: MRP6_RAT

General Information:
Name(s) found:	MRP6_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|T42216 multidrug resistance-associated protein homolog MLP-1 - rat [NCBI NR] gi\|7387886\|sp\|O88269.1\|MRP6_RAT RecName: Full=Multidrug resistance-associated protein 6; AltName: Full=ATP-binding cassette sub-family C member 6; AltName: Full=MRP-like protein 1; Short=MLP-1 [NCBI NR] gi\|4225852\|gb\|AAD12747.1\| multidrug resistance-associated protein 6 [Rattus norvegicus] [NCBI NR] gi\|3242458\|dbj\|BAA28954.1\| multidrug resistance-associated protein (MRP)-like protein-1 (MLP-1) [Rattus norvegicus] [NCBI NR] gi\|13591916\|ref\|NP_112275.1\| ATP-binding cassette, sub-family C (CFTR/MRP), member 6 [Rattus norvegicus] [NCBI NR] Multidrug resistance-associated protein 6 OS=Rattus norvegicus GN=Abcc6 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):1-94686940 Multidrug resistance-associated protein 6 [hmr_yeast5_DM3-1_pombe.fasta] liver multidrug resistance-associated protein 6 [HMR_022704-rand.fasta] ATP-binding cassette, sub-family C (CFTR/MRP), member 6 [Rattus norvegicus]gi\|4225852\|gb\|AAD12747.1\| multidrug resistance-associated protein 6 [Rattus norvegicus]gi\|7514016\|pir\|\|T42216 multidrug resistance-associated protein homolog MLP-1 - ratgi\|32424 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Multidrug resistance-associated protein 6 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_031013) liver multidrug resistance-associated protein 6 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Multidrug resistance-associated protein 6 (ATP-binding cassette sub-family C member 6) (MRP-like protein 1) (MLP-1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] ATP-binding cassette, sub-family C (CFTR/MRP), member 6 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] multidrug resistance-associated protein 6 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] multidrug resistance-associated protein (MRP)-like protein-1 (MLP-1) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 6 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Abcc6 Multidrug resistance-associated protein 6 [rat-ipi-250309-contam.fasta] Multidrug resistance-associated protein 6 OS=Rattus norvegicus GN=Abcc6 [011711_HMR.fasta] Multidrug resistance-associated protein 6 OS=Rattus norvegicus GN=Abcc6 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	1502 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] lateral plasma membrane [IDA] membrane [IEA] integral to membrane [IEA] apical plasma membrane [IDA]
Biological Process:	transmembrane transport [IEA] ATP catabolic process [IDA]
Molecular Function:	nucleotide binding [IEA] ATPase activity [IDA] ATP binding [IDA] ATPase activity, coupled to transmembrane movement of substances [IEA] transporter activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGEHSMATP GESCAGLRVW NQTEQEPVAY HLLNLCFLRA AGSWVPPMYL WVLGPIYLLY  60
   61 IHRHGCCYLR MSRLFKIKMV LGFALILLYT FNAAVPLWRI HRGMPQAPEL LIHPTVWLTT 120
  121 MSFATFLIHM ERKKGVRASG LLFGYWLLCC LVPAIDTVQQ ASAGSFRQEP LHHLATYLCL 180
  181 SLVVAELVLS CLVDQPPFFS EDSKPLNPCP EAEASFPSKA MFWWASGLLW KGYRKLLGPK 240
  241 DLWSLERENS SEELVSQLER EWRRNFSELP GHKGHSGMGT PETEAFLQPE RSQRGPLLRA 300
  301 IWRVFRSTFL LGTLSLVISD AFRFAVPKLL SLFLEFMGDL ESSAWTGWLL AVLMFLSACL 360
  361 QTLFEQQYMY RVKVLQMRLR TAITGLVYRK VLVLSSGSRK SSAAGDVVNL VSVDVQRLVE 420
  421 SILHLNGLWL LFLWIIVCFV YLWQLLGPSA LTAVAVFLSL LPLNFFITKK RSFHQEEQMR 480
  481 QKASRARLTS SMLRTVRTIK SHGWECAFLE RLLHIRGQEL GALKTSAFLF SVSLVSFQVS 540
  541 TFLVALVVFA VHTLVAEDNA MDAEKAFVTL TVLSILNKAQ AFLPFSVHCL VQARVSFDRL 600
  601 AAFLCLEEVD PNGMVLSPSR CSSKDRISIH NGTFAWSQES PPCLHGINLT VPQGCLLAVV 660
  661 GPVGAGKSSL LSALLGELLK VEGSVSIEGS VAYVPQEAWV QNTSVVENVC FRQELDLPWL 720
  721 QEVLEACALG SDVASFPAGV HTPVGEQGMN LSGGQKQRLS LARAVYRRAA VYLMDDPLAA 780
  781 LDAHVSQEVF KQVIGPSGLL QGTTRILVTH TLHVLPQADQ ILVLANGTIA EMGSYQDLLH 840
  841 RNGALVGLLD GARQPAGEGE GEAHAAATSD DLGGFSGGGT PTRRPERPRP SDAAPVKGST 900
  901 SEAQMEPSLD DVEVTGLTAG EDSVQYGRVK SATYLSYLRA VGTPLCTYTL FLFLCQQVAS 960
  961 FCQGYWLSLW ADDPVVDGKQ MHSALRGSIF GLLGCLQAIG LFASMAAVFL GGARASCLLF1020
 1021 RSLLWDVARS PIGFFERTPV GNLLNRFSKE TDIVDVDIPD KMRTLLTYAF GLLEVGLAVS1080
 1081 MATPLAIVAI LPLMLLYAGF QSLYVATCCQ LRRLESASYS SVCSHLAETF QGSQVVRAFQ1140
 1141 AQGPFTAQHD ALMDENQRIS FPRLVADRWL AANLELLGNG LVFVAATCAV LSKAHLSAGL1200
 1201 AGFSVSAALQ VTQTLQWVVR SWTDLENSMV AVERVQDYVH TPKEAPWRLP SSAAQPLWPC1260
 1261 GGQIEFRDFG LRHRPELPMA VQGVSLKIHA GEKVGIVGRT GAGKSSLTWG LLRLQEATEG1320
 1321 GIWIDGVPIT DMGLHTLRSR ITIIPQDPVL FPGSLRMNLD LLQENTDEGI WAALETVQLK1380
 1381 AFVTSLPGQL QYECSGQGDD LSVGQKQLLC LARALLRKTQ ILILDEATAS VDPGTEIQMQ1440
 1441 AALERWFAQC TVLLIAHRLR SVMNCARVLV MDEGQVAESG SPAQLLAQKG LFYRLAQESG1500
 1501 LA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: MRP6_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: