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Protein Overview: TYSY_RAT

General Information:
Name(s) found: TYSY_RAT [Swiss-Prot]
Description(s) found:
Found 31 descriptions.
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  • Thymidylate synthase OS=Rattus norvegicus GN=Tyms PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 307 amino acids

    Gene Ontology:
    Cellular Component: soluble fraction [IDA]
    Biological Process: intestinal epithelial cell maturation [IEP]
    nucleotide biosynthetic process [IEA]
    response to drug [IEP]
    immortalization of host cell by virus [IEP]
    dUMP metabolic process [IDA]
    response to organophosphorus [UNKNOWN][IEA]
    response to glucocorticoid stimulus [IEP]
    dTMP biosynthetic process [IDA]
    organ regeneration [IEP]
    developmental growth [IEP]
    aging [IEP]
    cartilage development [IEP]
    Molecular Function: nucleotide binding [IDA]
    thymidylate synthase activity [IDA]
    cofactor binding [IDA]
    methyltransferase activity [IEA]
    transferase activity [IEA]
    folic acid binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLVEGSELQS GAQQPRTEAP QHGELQYLRQ VEHIMRCGFK KEDRTGTGTL SVFGMQARYS  60
   61 LRDEFPLLTT KRVFWKGVLE ELLWFIKGST NAKELSSKGV RIWDANGSRD FLDSLGFSAR 120
  121 QEGDLGPVYG FQWRHFGADY KDMDSDYSGQ GVDQLQKVID TIKTNPDDRR IIMCAWNPKD 180
  181 LPLMALPPCH ALCQFYVVNG ELSCQLYQRS GDMGLGVPFN IASYALLTYM IAHITGLQPG 240
  241 DFVHTLGDAH IYLNHIEPLK IQLQREPRPF PKLRILRKVE TIDDFKVEDF QIEGYNPHPT 300
  301 IKMEMAV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.82

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle