Protein Overview: gi|17864061

General Information:
Name(s) found:	gi\|17864061 [NCBI NR]
Description(s) found: SHOW ONLY BEST	gi\|17864061\|gb\|AAL47053.1\|AF452647_1 nesprin-1 [Rattus norvegicus] [NCBI NR] Ensembl_locations(Chr-bp):1-38765781;1-38765781 Nesprin-1 [hmr_yeast5_DM3-1_pombe.fasta] nesprin-1 [HMR_022704-rand.fasta] nesprin-1 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Nesprin-1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_134381) nesprin-1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 NESPRIN-1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Nesprin-1 OS=Rattus norvegicus GN=Syne1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	2838 amino acids
Gene Ontology:
Cellular Component:	nuclear envelope [UNKNOWN][IDA] perinuclear region of cytoplasm [IDA] postsynaptic membrane [UNKNOWN] dendritic spine [IDA] spindle [IDA] integral to membrane [UNKNOWN][IEA] Golgi apparatus [UNKNOWN][IDA] midbody [IDA] SUN-KASH complex [UNKNOWN] sarcomere [UNKNOWN]
Biological Process:	establishment of nucleus localization [UNKNOWN] Golgi organization [UNKNOWN] muscle cell differentiation [UNKNOWN] cytoskeletal anchoring at nuclear membrane [UNKNOWN] brain development [IEP] nuclear matrix anchoring at nuclear membrane [UNKNOWN] response to light stimulus [IEP] positive regulation of receptor-mediated endocytosis [IMP] regulation of dendrite morphogenesis [IMP]
Molecular Function:	protein binding [UNKNOWN][IDA] actin binding [UNKNOWN][IEA] structural molecule activity [TAS] lamin binding [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLSESLQPG RSPESQMAEH QALMDEVQML QDEINGLQAS LAEELVAESH ESDPAEQLAL  60
   61 QSTLTVLAER MSTIRMKAAG KRQLLEEKLN DQLEEQRQEQ ALQRYRCEAE ELDHWLLNTK 120
  121 ATLDFAAGIP QEPMDTDAQL VDCQNMLVEI EQKVVALSQL SVRSENLLLE GKAHTKDEAE 180
  181 QLASKLRMLK GSLMELQRAL RDRQLNMQGV TQEKEENDVD FTATQSPGVQ EWLAQARNTR 240
  241 THQRQSSLQQ QKEFEQELAE QKSLLRSVAS RGEEILIQHS TAEGSGGLGE KPDALSQELV 300
  301 MEGAKSFAED QMRAKWESLH QEFSTKQKLL QNILEQEQEQ MLYSSPNRLL SGVLPLRGEA 360
  361 QTQDKSSVTS LLDGLSQAFG EVSSQSGGTD RQNIHLEQKL YDGVSATSTW LDDVEEHLFV 420
  421 ATALLPEETE TCLFNQEALA KDIKEMSEEM DKNKNLFSQA FPEDSDNRDV IEDTLGCLLG 480
  481 RLSLLDSVVG QRCHQMKERL QQVLSFQNDL KVLFTSLADN NYIILQKLAN MFKQPIVEQI 540
  541 QAIQQAEEGL RELDGGISEL KQRGDKLQVD QSALQELSKL QDMYDELLVT ISSRRSNLNQ 600
  601 NLALKSQYDK ALQDLVDLLD TGQEKMAGDQ KIIVSSKEEV QQLLSKHKEY FQGLESHLIL 660
  661 TETLFRKIVD FAAMKETQLH SDRMAQASAV LKQAHKRGVE LEYILEMWSH LDENLQELSR 720
  721 QLEVIENSIP SVGLVEESED RLVERTSLYQ HLKSSLNEYQ PKLYQVLDDG KRLMMSISCS 780
  781 ELESQLNQLG ERWLGNTNKV SKELHRLETI LKHWTRYQSE AADLIHWLES AKDKLAFWTQ 840
  841 QSVTVPQELE MVRDHLNAFL EFSKEVDAKS SLKSSVTSTG NQLLRLKKVD TAALRAELSC 900
  901 MDSQWTDLLA GIPAVQEKLH QLQMDKLPSR HAISEVMSWI SLMESVILKD EEDIRNAIGY 960
  961 KAIYEYLQKY KGFKIDLNCK QLTADFVNQS VLQISSQDVE SKRSDKTDFA EQLGAMNKSW1020
 1021 QLLQGRVGEK IQMLEGLLES WSEYENSIQS LKAWFANQER KLEEHHQIGD QNSVQNALKD1080
 1081 CQELEDLIKA KEKEVEKIEQ NGLALIQNKR EEVSCSVLNT LWELRQTWAS LERTVGQLKI1140
 1141 QLTLVLGQWS IHKAAFEEIS NHLMEARYSL SRFRLLTGSS DAVQVQVDNL QNLHDDLEKQ1200
 1201 EGDLQKFGSL TNHLLKECHP PVAEALSSTL QEVNMRWNNL LEEIAKQLHS SKALLQLWQR1260
 1261 YKDYSKQCAS AVQRQEEQTN ALLKAATSKD IADDEVAKWI QDCNDLLKGL GTVKDSLFIL1320
 1321 HELGEQLGQQ VDDSAATTIQ CEQLCFSQRL EALEQALCKQ QAVLQAGVVD YETFAKSLEA1380
 1381 LEAWIVEAEG ILQAQDPTHS SDLSTIQERM EELKGQMLKF SSMAPDLDRL NELGYRLPLN1440
 1441 DKEIKRMQNL NRHWSLISSQ TTERFSKLQS FLLQHQTFLE KCETWMEFLV QTEHKLAVEI1500
 1501 SGNYQHLLEQ QRAHELFQAE MFSRQQILHS IIVDGQNLLE QGQVDDREEF SLKLTLLSNQ1560
 1561 WQGVIRRAQQ RRGIIDSQIR QWQRYREMAE KLRKWLVEVS HLPLSGLGSI PVPLQQVRTL1620
 1621 FDEVQFKEKV FLRQQGSYIL TVEAGKQLLL SADSGAEAAL QAELTDIQEK WKSASTHLEE1680
 1681 QKKKLAFLLK DWEKCEKGIA DSLEKLRTFK KRLSQPLPDH HEELHAEQMR CKELENAVGR1740
 1741 WTDDLAELVL LREALAAHLS AEDISILKER VELLQRQWEE LCHQVSLRRQ QVSERLNEWA1800
 1801 VFSEKNKELC EWLTQMESKV SQNGDILIEE MIEKLKKDYQ EKIAVAQENK IQLQQMGERL1860
 1861 AKASHESKAS EIQYKLSKVN DRWQHLLDLM AARVKKLKET LVAVQQLDKN MGSLRIWLAH1920
 1921 MESELAKPIV YDSCNSEEIQ KKLSEQQELQ RDIEKHSTGV ASVLNLCEVL LHDCDACATD1980
 1981 AECDSIQQAT RNLDRRWRNI CAMSMERRLK IEETWRLWQK FLDDYSRFED WLEISERTAA2040
 2041 FPSSSGVLYT VAKEELKKFE AFQRQVHESL TQLELINKQY RRLARENRTD SACSLRQMAH2100
 2101 GGNQRWDDLL KRVTSILRRL KHFISQREEF ETARDSILVW LTEMDLQLTN IEHFSECDVQ2160
 2161 AKIKQLKAFQ QEISLNHSKI EQIIAQGEQL IEKSEPLDAA VIEEELDELR RYCQEVFGRV2220
 2221 ERYHKKLIRL PLPDDHDLSD RELDLEDSMA LSDLHWQDPS EDGMPSPQPS SNPSLSLPQP2280
 2281 LRSERSGRDT PASVDSIPLE WDHDYDHDYD LSRDLESASR TLPSEDEEGE EDKEFYLRGA2340
 2341 VGLSDVVIPE NPEAYVKLTE NAIRNTSGDP TSLESQMRQL DKALDDSRFQ IQQTANILRG2400
 2401 KTPTGPDLGT SYKGYMKLLG ECSGTIDSVR RLEHKLAEEE SFPGFTNPTS TETQPAGVID2460
 2461 RWELLQAQAM SKELKMKQNL QKWQQFNSDL NNICAWLGET EEELDRLQHL ALSTVIHTIK2520
 2521 SHIKKLKELQ KALDHRKAII LSINLCSSEF TQADSKESHD LQDRLSQMNR RWDRVCSLLE2580
 2581 DWRGSLQDAL MQCQDFHEMT HALLLLLENT DRRKNEIVPI DSTLDPETLQ DHHTQLTQIK2640
 2641 QELLKSQLRV ASLQNMSRQL LVNAEGSDCL EAKEKVHVIG NRLKLLLKEV SRHIKDLEKL2700
 2701 LGMSSSQQDL SSWSSADEVD TSGSVSPTSG RSTPNRQKSP RGKCSLSQPG PSVSSPKSRS2760
 2761 TKGGSDSSLS ETRPARAGRD FLFRVLRAAL PIQLLLLLLI GLTSRVPISE EDYSCALSNN2820
 2821 FARSFHPMLR YTNGPPPL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.81

Protein Overview: gi|17864061

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: