Protein Overview: LPH_RAT

General Information:
Name(s) found:	LPH_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|JS0610 beta-galactosidase (EC 3.2.1.23) / glycosylceramidase (EC 3.2.1.62) precursor - rat [NCBI NR] gi\|6648054\|sp\|Q02401.2\|LPH_RAT RecName: Full=Lactase-phlorizin hydrolase; AltName: Full=Lactase-glycosylceramidase; Includes: RecName: Full=Lactase; Includes: RecName: Full=Phlorizin hydrolase; Flags: Precursor [NCBI NR] Lactase-phlorizin hydrolase OS=Rattus norvegicus GN=Lct PE=2 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):13-35043552 Lactase-phlorizin hydrolase precursor [hmr_yeast5_DM3-1_pombe.fasta] beta-galactosidase (EC 3.2.1.23) / glycosylceramidase (EC 3.2.1.62) precursor - ratgi\|6648054\|sp\|Q02401\|LPH_RAT Lactase-phlorizin hydrolase precursor (Lactase-glycosylceramidase) [Includes: Lactase ; Phlorizin hydrolase ] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Lactase-phlorizin hydrolase precursor [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] Lactase-phlorizin hydrolase precursor (Lactase-glycosylceramidase) [Includes: Lactase ; Phlorizin hydrolase ] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 LACTASE-PHLORIZIN HYDROLASE PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Lct Lactase-phlorizin hydrolase [rat-ipi-250309-contam.fasta] Lactase-phlorizin hydrolase OS=Rattus norvegicus GN=Lct [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1928 amino acids
Gene Ontology:
Cellular Component:	brush border [IDA] integral to membrane [IEA] plasma membrane [UNKNOWN][IEA] apical plasma membrane [IEA]
Biological Process:	response to organic substance [IDA] response to estrogen stimulus [IEP] response to iron(II) ion [IDA] metabolic process [IEA] response to starvation [IEP] response to nutrient [IDA] response to hormone stimulus [IEP] response to sucrose stimulus [IEP] carbohydrate metabolic process [IEA] response to ethanol [IDA] response to hypoxia [IDA] response to drug [IDA] response to lead ion [IDA] response to nickel ion [IDA]
Molecular Function:	glycosylceramidase activity [IEA] cation binding [IEA] lactase activity [UNKNOWN][IDA] transferase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELPWTALFL STVLLGLSCQ GSDWESDRNF ISAAGPLTND LVLNLNYPPG KQGSDVVSGN  60
   61 TDHLLCQQPL PSFLSQYFSS LRASQVTHYK VLLSWAQLLP TGSSKNPDQE AVQCYRQLLQ 120
  121 SLKDAQLEPM VVLCHQTPPT SSAIQREGAF ADLFADYATL AFQSFGDLVE IWFTFSDLEK 180
  181 VIMDLPHKDL KASALQTLSN AHRRAFEIYH RKFSSQGGKL SVVLKAEDIP ELLPDPALAA 240
  241 LVQGSVDFLS LDLSYECQSV ATLPQKLSEL QNLEPKVKVF IYTLKLEDCP ATGTSPSSLL 300
  301 ISLLEAINKD QIQTVGFDVN AFLSCTSNSE ESPSCSLTDS LALQTEQQQE TAVPSSPGSA 360
  361 YQRVWAAFAN QSREERDAFL QDVFPEGFLW GISTGAFNVE GGWAEGGRGP SIWDHYGNLN 420
  421 AAEGQATAKV ASDSYHKPAS DVALLRGIRA QVYKFSISWS GLFPLGQKST PNRQGVAYYN 480
  481 KLIDRLLDSH IEPMATLFHW DLPQALQEQG GWQNESVVEA FLDYAAFCFS TFGDRVKLWV 540
  541 TFHEPWVMSY AGYGTGQHAP AISDPGMASF KVAHLILKAH ARTWHLYDLH HRLQQQGRVG 600
  601 IVLNSDLAEP LDRKSPQDLA AAERFLHFML GWFAHPIFVD GDYPTTSAQI QHINQQCGHP 660
  661 LAQLPEFTEA EKRLLKGSAD FLGLSHYTSR LISKAGRQTC TSSYDNIGGF SQHVDPEWPQ 720
  721 TASPWIRVVP WGIRRLLRFA SMEYTKGKLP IFLAGNGMPV GEEADLFDDS VRVNYFNWYI 780
  781 NEVLKAVKED LVDVRSYIVR SLIDGYEGPL GFSQRFGLYH VNFNDSSRPR TPRKSAYLFT 840
  841 SIIEKNGFSA KKVKRNPLPV RADFTSRARV TDSLPSEVPS KAKISVEKFS KQPRFERDLF 900
  901 YDGRFRDDFL WGVSSSPYQI EGGWNADGKG PSIWDNFTHT PGNGVKDNAT GDVACDSYHQ 960
  961 LDADLNILRT LKVKSYRFSI SWSRIFPTGR NSTINKQGVD YYNRLIDSLV DNNIFPMVTL1020
 1021 FHWDLPQALQ DIGGWENPSL IELFDSYADY CFKTFGDRVK FWMTFNEPWC HVVLGYSSGI1080
 1081 FPPSVQEPGW LPYKVSHIVI KAHARVYHTY DEKYRSEQKG VISLSLNTHW AEPKDPGLQR1140
 1141 DVEAADRMLQ FTMGWFAHPI FKNGDYPDVM KWTVGNRSEL QHLASSRLPT FTEEEKNYVR1200
 1201 GTADVFCHNT YTSVFVQHST PRLNPPSYDD DMELKLIEMN SSTGVMHQDV PWGTRRLLNW1260
 1261 IKEEYGNIPI YITENGQGLE NPTLDDTERI FYHKTYINEA LKAYKLDGVD LRGYSAWTLM1320
 1321 DDFEWLLGYT MRFGLYYVDF NHVSRPRTAR ASARYYPDLI ANNGMPLARE DEFLYGEFPK1380
 1381 GFIWSAASAS YQVEGAWRAD GKGLSIWDTF SHTPLRIGND DNGDVACDSY HKIAEDVVAL1440
 1441 QNLGVSHYRF SIAWSRILPD GTTKFINEAG LSYYVRFIDA LLAAGITPQV TIYHWDLPQA1500
 1501 LQDVGGWENE TIVQRFKEYA DVLFQRLGDR VKFWITLNEP FVIAAQGYGT GVSAPGISFR1560
 1561 PGTAPYIAGH NLIKAHAEAW HLYNDVYRAR QGGTISITIS SDWGEPRDPT NREHVEAARS1620
 1621 YVQFMGGWFA HPIFKNGDYP EVMKTRIRDR SLGAGLNKSR LPEFTESEKS RIKGTFDFFG1680
 1681 FNHNTTVLAY NLDYPAAFSS FDADRGVASI ADSSWPVSGS FWLKVTPFGF RRILNWLKEE1740
 1741 YNNPPIYVTE NGVSRRGEPE LNDTDRIYYL RSYINEALKA VHDKVDLRGY TVWSIMDNFE1800
 1801 WATGFAERFG VHFVNRSDPS LPRIPRASAK FYATIVRCNG FPDPAQGPHP CLQQPEDAAP1860
 1861 TASPVQSEVP FLGLMLGIAE AQTALYVLFA LLLLGACSLA FLTYNTGRRS KQGNAQPSQH1920
 1921 QLSPISSF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: LPH_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: