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Protein Overview: SHAN1_RAT

General Information:
Name(s) found: SHAN1_RAT [Swiss-Prot]
Description(s) found:
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  • gi|77627981|ref|NP_113939.2| SH3 and multiple ankyrin repeat domains 1 [Rattus norvegicus] [NCBI NR]
  • gi|5381426|gb|AAD42975.1|AF159046_1 SPANK-1 [Rattus norvegicus] [NCBI NR]
  • gi|22001985|sp|Q9WV48.1|SHAN1_RAT RecName: Full=SH3 and multiple ankyrin repeat domains protein 1; Short=Shank1; AltName: Full=GKAP/SAPAP-interacting protein; AltName: Full=SPANK-1; AltName: Full=Synamon; AltName: Full=Somatostatin receptor-interacting pr [NCBI NR]
  • (Q9WV48) SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (GKAP/SAPAP interacting protein) (SPANK-1) (Synamon) (Somatostatin receptor interacting protein) (SSTR interacting protein) (SSTRIP) [Swiss-Prot]
  • SH3 and multiple ankyrin repeat domains protein 1 OS=Rattus norvegicus GN=Shank1 PE=1 SV=1 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):None Splice isoform 1 of Q9WV48 [hmr_yeast5_DM3-1_pombe.fasta]
  • SPANK-1 [Rattus norvegicus]gi|22001985|sp|Q9WV48|SHK1_RAT SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (GKAP/SAPAP interacting protein) (SPANK-1) (Synamon) (Somatostatin receptor interacting protein) (SSTR interacting protein) (SSTRIP) [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Splice Isoform 1 of SH3 and multiple ankyrin repeat domains protein 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (GKAP/SAPAP-interacting protein) (SPANK-1) (Synamon) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • SH3/ankyrin domain gene 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • SPANK-1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 SPLICE ISOFORM 1 OF SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • SH3 and multiple ankyrin repeat domains 1 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Shank1 Isoform 1 of SH3 and multiple ankyrin repeat domains protein 1 [rat-ipi-250309-contam.fasta]
  • Isoform 1 of SH3 and multiple ankyrin repeat domains protein 1 OS=Rattus norvegicus GN=Shank1 [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 2167 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [UNKNOWN][IDA]
    postsynaptic density [IEA]
    dendrite [NAS]
    cytoplasm [IEA]
    postsynaptic membrane [UNKNOWN][IDA]
    cell junction [IEA]
    synapse [IEA]
    intracellular [NAS]
    plasma membrane [IEA]
    Biological Process: cytoskeletal anchoring at plasma membrane [NAS]
    Molecular Function: somatostatin receptor binding [IPI]
    protein binding [UNKNOWN][IEA][IPI]
    receptor signaling complex scaffold activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTHSPATSED EERHSASECP EGGSESDSSP DGPGRGPQGT RGRGSGAPGN LASTRGLQGR  60
   61 SMSVPDDAHF SMMVFRIGIP DLHQTKCLRF NPDATIWTAK QQVLCALSES LQDVLNYGLF 120
  121 QPATSGRDAN FLEEERLLRE YPQSFEKGVP YLEFRYKTRV YKQTNLDEKQ LAKLHTKTGL 180
  181 KKFLEYVQLG TSDKVARLLD KGLDPNYHDS DSGETPLTLA AQTEGSVEVI RTLCLGGAHI 240
  241 DFRARDGMTA LHKAACARHC LALTALLDLG GSPNYKDRRG LTPLFHTAMV GGDPRCCELL 300
  301 LYNRAQLGIA DENGWQEIHQ ACQRGHSQHL EHLLFYGAEP GAQNASGNTA LHICALYNKE 360
  361 TCARILLYRG ANKDVKNNNG QTPFQVAVIA GNFELGELIR NHREQDVVPF QESPKYAARR 420
  421 RGPPGAGLTV PPALLRANSD TSMALPDWMV FSAPGASSSG TPGPTSGPQG QSQPSAPSTK 480
  481 LSSGTLRSAS SPRGARARSP SRGRHPEDAK RQPRGRPSSS GTPRDGPAGG TGGSGGPGGS 540
  541 LGSRGRRRKL YSAVPGRSFM AVKSYQAQGE GEISLSKGEK IKVLSIGEGG FWEGQVKGRV 600
  601 GWFPSDCLEE VANRSQEGRQ ESRSDKAKRL FRHYTVGSYD SFDAPSLIDG IDSGSDYIIK 660
  661 EKTVLLQKKD SEGFGFVLRG AKAQTPIEEF TPTPAFPALQ YLESVDEGGV AWRAGLRMGD 720
  721 FLIEVNGQNV VKVGHRQVVN MIRQGGNTLM VKVVMVTRHP DMDEAVHKKA SQQAKRLPPP 780
  781 AISLRSKSMT SELEEMVSPW KKKIEYEQQP AAVPSMEKKR TVYQMALNKL DEILAAAQQT 840
  841 ISASESPGPG GLASLGKHRP KGFFATESSF DPHHRSQPSY DRPSFLPPGP GLMLRQKSIG 900
  901 AAEDDRPYLA PPAMKFSRSL SVPGSEDIPP PPTTSPPEPP YSTPPAPSSS GRLTPSPRGG 960
  961 PFNPSSGGPL PASSPSSFDG PSPPDTRGGG REKSLYHSAA LPPAHHHPPH HHHHHAPPPQ1020
 1021 PHHHHAHPPH PPEMETGGSP DDPPPRLALG PQPSLRGWRG GGPSPTSGAP SPSHHSSSGG1080
 1081 SSGPTQAPAL RYFQLPPRAA SAAMYVPARS GRGRKGPLVK QTKVEGEPQK GSIPSASSPT1140
 1141 SPALPRSEPP PAGPSEKNSI PIPTIIIKAP STSSSGRSSQ GSSTEAEPPT QPDGAGGGGS1200
 1201 SPSPAPATSP VPPSPSPVPT PASPSGPATL DFTSQFGAAL VGAARREGGW QNEARRRSTL1260
 1261 FLSTDAGDED GGDSGLGPGG PPGPRLRHSK SIDEGMFSAE PYLRLESGGS SGGYGAYAAG1320
 1321 SRAYGGSGSS SAFTSFLPPR PLVHPLTGKA LDPASPLGLA LAARERALKE SSEGGGTPQP1380
 1381 PPRPPSPRYD APPPTLHHHS PHSPHSPHAR HEPVLRLWGD PARRELGYRA GLGSQEKALT1440
 1441 ASPPAARRSL LHRLPPTAPG VGPLLLQLGP EPPTPHPGVS KAWRTAAPEE PERLPLHVRF1500
 1501 LENCQARPPP AGTRGSSTED GPGVPPPSPR RVLPTSPTSP RGNEENGLPL LVLPPPAPSV1560
 1561 DVDDGEFLFA EPLPPPLEFS NSFEKPESPL TPGPPHPLPD PPSPATPLPA APPPAVAAAP1620
 1621 PTLDSTASSL TSYDSEVATL TQGAPAAPGD PPAPGPPAPA APAPPAPQPG PDPPPGTDSG1680
 1681 IEEVDSRSSS DHPLETISSA STLSSLSAEG GGNTGGVAGG GAGVASGTEL LDTYVAYLDG1740
 1741 QAFGGSGTPG PPYPPQLMTP SKLRGRALGT SGNLRPGPSG GLRDPVTPTS PTVSVTGAGT1800
 1801 DGLLALSACP GPSTAGVAGG PVAVEPEVPP VPLPAASSLP RKLLPWEEGP GPPPPPLPGP1860
 1861 LSQPQASALA TVKASIISEL SSKLQQFGGS STAGGALPWA RGGSGGSTDS HHGGASYIPE1920
 1921 RTSSLQRQRL SEDSQTSLLS KPSSSIFQNW PKPPLPPLPT GSGVSSSTAA APGATSPSAS1980
 1981 SASASTRHLQ GVEFEMRPPL LRRAPSPSLL PASDHKVSPA PRPSSLPILP SGPIYPGLFD2040
 2041 IRSSPTGGAG GSTDPFAPVF VPPHPGISGG LGGALSGASR SLSPTRLLSL PPDKPFGAKP2100
 2101 LGFWTKFDVA DWLEWLGLSE HRAQFLDHEI DGSHLPALTK EDYVDLGVTR VGHRMNIDRA2160
 2161 LKFFLER

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle