YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: MRP2_RAT

General Information:
Name(s) found: MRP2_RAT [Swiss-Prot]
Description(s) found:
SHOW ONLY BEST
  • gi|6978669|ref|NP_036965.1| ATP-binding cassette, sub-family C (CFTR/MRP), member 2 [Rattus norvegicus] [NCBI NR]
  • gi|3219824|sp|Q63120.1|MRP2_RAT RecName: Full=Canalicular multispecific organic anion transporter 1; AltName: Full=ATP-binding cassette sub-family C member 2; AltName: Full=Multidrug resistance-associated protein 2; AltName: Full=Canalicular multidrug res [NCBI NR]
  • pir||S71839 canalicular multidrug resistance protein - rat [NCBI NR]
  • gi|1617207|emb|CAA65257.1| canalicular multidrug resistance protein [Rattus norvegicus] [NCBI NR]
  • gi|1280389|gb|AAC42087.1| organic anion transporter [NCBI NR]
  • Canalicular multispecific organic anion transporter 1 OS=Rattus norvegicus GN=Abcc2 PE=1 SV=1 [Swiss-Prot]
  • Ensembl_locations(Chr-bp):1-241237004 Canalicular multispecific organic anion transporter 1 [hmr_yeast5_DM3-1_pombe.fasta]
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 2; Canalicular multispecific organic anion transporter; multidrug resistance associated protein 2; ATP-binding cassette sub-family C (CFTR/MRP) member 2; calicular multispecific organic anion transport [HMR_022704-rand.fasta]
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 2; multidrug resistance associated protein 2; ATP-binding cassette sub-family C (CFTR/MRP) member 2; calicular multispecific organic anion transporter; Canalicular multispecific organic anion transport [071204_hmrz_cont.fasta]
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 2 [Rattus norvegicus]gi|1617207|emb|CAA65257.1| canalicular multidrug resistance protein [Rattus norvegicus]gi|2143644|pir||S71839 canalicular multidrug resistance protein - ratgi|1280389|gb|AAC4208 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Canalicular multispecific organic anion transporter 1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • (NM_012833) ATP-binding cassette, sub-family C (CFTR/MRP), member 2; Canalicular multispecific organic anion transporter [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • Canalicular multispecific organic anion transporter 1 (ATP-binding cassette sub-family C member 2) (Multidrug resistance-associated protein 2) (Canalicular multidrug resistance protein) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • canalicular multidrug resistance protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • organic anion transporter [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 CANALICULAR MULTISPECIFIC ORGANIC ANION TRANSPORTER 1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Abcc2 Canalicular multispecific organic anion transporter 1 [rat-ipi-250309-contam.fasta]
  • canalicular multispecific organic anion transporter 1 [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
  • Canalicular multispecific organic anion transporter 1 OS=Rattus norvegicus GN=Abcc2 [011711_HMR.fasta]
  • Canalicular multispecific organic anion transporter 1 OS=Rattus norvegicus GN=Abcc2 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
    • Organism: Rattus norvegicus
    Length: 1541 amino acids

    Gene Ontology:
    Cellular Component: membrane fraction [UNKNOWN]
    intercellular canaliculus [UNKNOWN]
    integral to plasma membrane [UNKNOWN]
    membrane [IDA]
    integral to membrane [IEA]
    apical plasma membrane [UNKNOWN]
    Biological Process: response to oxidative stress [IEP]
    drug transmembrane transport [IMP]
    response to heat [IEP]
    response to methotrexate [IEP]
    response to estrogen stimulus [IDA]
    response to arsenic [IEP]
    response to drug [IDA]
    response to steroid hormone stimulus [IEP]
    organic anion transport [TAS]
    cellular chloride ion homeostasis [IDA]
    prostaglandin transport [IMP]
    thyroid hormone transport [IMP]
    Molecular Function: nucleotide binding [IEA]
    ATPase activity [IEA]
    ATP binding [IEA]
    protein domain specific binding [IPI]
    ATPase activity, coupled to transmembrane movement of substances [IEA]
    protein binding [UNKNOWN]
    organic anion transmembrane transporter activity [TAS]
    transporter activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKFCNSTFW DLSLLESPEA DLPLCFEQTV LVWIPLGFLW LLAPWQLYSV YRSRTKRSSI  60
   61 TKFYLAKQVF VVFLLILAAI DLSLALTEDT GQATVPPVRY TNPILYLCTW LLVLAVQHSR 120
  121 QWCVRKNSWF LSLFWILSVL CGVFQFQTLI RALLKDSKSN MAYSYLFFVS YGFQIVLLIL 180
  181 TAFSGPSDST QTPSVTASFL SSITFSWYDR TVLKGYKHPL TLEDVWDIDE GFKTRSVTSK 240
  241 FEAAMTKDLQ KARQAFQRRL QKSQRKPEAT LHGLNKKQSQ SQDVLVLEEA KKKSEKTTKD 300
  301 YPKSWLIKSL FKTFHVVILK SFILKLIHDL LVFLNPQLLK LLIGFVKSSN SYVWFGYICA 360
  361 ILMFAVTLIQ SFCLQSYFQH CFVLGMCVRT TVMSSIYKKA LTLSNLARKQ YTIGETVNLM 420
  421 SVDSQKLMDA TNYMQLVWSS VIQITLSIFF LWRELGPSIL AGVGVMVLLI PVNGVLATKI 480
  481 RNIQVQNMKN KDKRLKIMNE ILSGIKILKY FAWEPSFQEQ VQGIRKKELK NLLRFGQLQS 540
  541 LLIFILQITP ILVSVVTFSV YVLVDSANVL NAEKAFTSIT LFNILRFPLS MLPMVTSSIL 600
  601 QASVSVDRLE RYLGGDDLDT SAIRRVSNFD KAVKFSEASF TWDPDLEATI QDVNLDIKPG 660
  661 QLVAVVGTVG SGKSSLVSAM LGEMENVHGH ITIQGSTAYV PQQSWIQNGT IKDNILFGSE 720
  721 YNEKKYQQVL KACALLPDLE ILPGGDMAEI GEKGINLSGG QKQRVSLARA AYQDADIYIL 780
  781 DDPLSAVDAH VGKHIFNKVV GPNGLLAGKT RIFVTHGIHF LPQVDEIVVL GKGTILEKGS 840
  841 YRDLLDKKGV FARNWKTFMK HSGPEGEATV NNDSEAEDDD DGLIPTMEEI PEDAASLAMR 900
  901 RENSLRRTLS RSSRSSSRRG KSLKNSLKIK NVNVLKEKEK EVEGQKLIKK EFVETGKVKF 960
  961 SIYLKYLQAV GWWSILFIIL FYGLNNVAFI GSNLWLSAWT SDSDNLNGTN NSSSHRDMRI1020
 1021 GVFGALGLAQ GICLLISTLW SIYACRNASK ALHGQLLTNI LRAPMRFFDT TPTGRIVNRF1080
 1081 SGDISTVDDL LPQTLRSWMM CFFGIAGTLV MICMATPVFA IIIIPLSILY ISVQVFYVAT1140
 1141 SRQLRRLDSV TKSPIYSHFS ETVTGLPIIR AFEHQQRFLA WNEKQIDINQ KCVFSWITSN1200
 1201 RWLAIRLELV GNLVVFCSAL LLVIYRKTLT GDVVGFVLSN ALNITQTLNW LVRMTSEAET1260
 1261 NIVAVERISE YINVENEAPW VTDKRPPADW PRHGEIQFNN YQVRYRPELD LVLKGITCNI1320
 1321 KSGEKVGVVG RTGAGKSSLT NCLFRILESA GGQIIIDGID VASIGLHDLR ERLTIIPQDP1380
 1381 ILFSGSLRMN LDPFNKYSDE EVWRALELAH LRSFVSGLQL GLLSEVTEGG DNLSIGQRQL1440
 1441 LCLGRAVLRK SKILVLDEAT AAVDLETDSL IQTTIRKEFS QCTVITIAHR LHTIMDSDKI1500
 1501 MVLDNGKIVE YGSPEELLSN RGSFYLMAKE AGIENVNHTE L

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle