General Information: |
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Name(s) found: |
IL6RA_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 462 amino acids |
Gene Ontology: |
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Cellular Component: |
extracellular space
[UNKNOWN][IDA]
membrane [IEA] integral to membrane [IEA] extracellular region [UNKNOWN][IEA] apical plasma membrane [UNKNOWN][IEA] interleukin-6 receptor complex [UNKNOWN][IEA] cell surface [UNKNOWN][IEA] |
Biological Process: |
response to cytokine stimulus
[UNKNOWN][IEA]
positive regulation of tyrosine phosphorylation of Stat3 protein [UNKNOWN][IEA] positive regulation of cell proliferation [UNKNOWN] response to cAMP [IEP] positive regulation of anti-apoptosis [UNKNOWN][IEA] [NOT]positive regulation of NF-kappaB transcription factor activity [UNKNOWN] positive regulation of smooth muscle cell proliferation [UNKNOWN][IEA] response to ethanol [IEP] negative regulation of collagen biosynthetic process [UNKNOWN] cytokine-mediated signaling pathway [UNKNOWN] ciliary neurotrophic factor-mediated signaling pathway [UNKNOWN][IEA] response to glucocorticoid stimulus [IEP] positive regulation of activation of Janus kinase activity [UNKNOWN] interleukin-6-mediated signaling pathway [UNKNOWN][IEA] response to gamma radiation [IEP] positive regulation of chemokine production [UNKNOWN][IEA] endocrine pancreas development [UNKNOWN] positive regulation of peptidyl-tyrosine phosphorylation [UNKNOWN][IEA] defense response to Gram-positive bacterium [UNKNOWN] defense response to Gram-negative bacterium [UNKNOWN][IEA] positive regulation of MAPKKK cascade [UNKNOWN] response to peptide hormone stimulus [IEP] negative regulation of interleukin-8 production [UNKNOWN] response to lipopolysaccharide [IEP] positive regulation of interleukin-6 production [UNKNOWN][IEA] |
Molecular Function: |
ciliary neurotrophic factor receptor activity
[UNKNOWN][IEA]
protein binding [UNKNOWN] protein homodimerization activity [UNKNOWN][IEA] interleukin-6 receptor activity [UNKNOWN][IMP] interleukin-6 binding [UNKNOWN] receptor activity [IEA] ciliary neurotrophic factor binding [UNKNOWN][IEA] interleukin-6 receptor binding [UNKNOWN][IEA] enzyme binding [UNKNOWN][IEA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MLAVGCTLLV ALLAAPAVAL VLGSCRALEV ANGTVTSLPG ATVTLICPGK EAAGNATIHW 60 61 VYSGSQSREW TTTGNTLVLR AVQVNDTGHY LCFLDDHLVG TVPLLVDVPP EEPKLSCFRK 120 121 NPLVNAFCEW HPSSTPSPTT KAVMFAKKIN TTNGKSDFQV PCQYSQQLKS FSCEVEILEG 180 181 DKVYHIVSLC VANSVGSRSS HNVVFQSLKM VQPDPPANLV VSAIPGXPRW LKVSWQDPES 240 241 WDPSYYLLQF ELRYRPVWSK XFTVWPLQVA QHQCVIHDAL RGVKHVVQVR GKEEFDIGQW 300 301 SKWSPEVTGT PWLAEPRTTP AGIPGNPTQV SVEDYDNHED QYGSSTEATS VLAPVQGSSP 360 361 IPLPTFLVAG GSLAFGLLLC VFIILRLKKK WKSQAEKESK TTSPPPYPLG PLKPTFLLVP 420 421 LLTPSGSHNS SGTDNTGSHS CLGVRDPQCP NDNSNRDYLF PR |
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