Protein Overview: HEM3_RAT

General Information:
Name(s) found:	HEM3_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|2506505\|sp\|P19356.2\|HEM3_RAT RecName: Full=Porphobilinogen deaminase; Short=PBG-D; AltName: Full=Pre-uroporphyrinogen synthase; AltName: Full=Hydroxymethylbilane synthase; Short=HMBS [NCBI NR] pir\|\|IBRTE hydroxymethylbilane synthase (EC 4.3.1.8), nonerythroid splice form - rat [NCBI NR] Porphobilinogen deaminase OS=Rattus norvegicus GN=Hmbs PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):8-45893169 Splice isoform 1 of P19356 [hmr_yeast5_DM3-1_pombe.fasta] hemC [Rattus sp.]gi\|2506505\|sp\|P19356\|HEM3_RAT Porphobilinogen deaminase (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) (PBG-D)gi\|11379903\|pir\|\|IBRTE hydroxymethylbilane synthase (EC 4.3.1.8), nonerythroid splice form - rat [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Porphobilinogen deaminase [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Porphobilinogen deaminase (PBG-D) (Pre-uroporphyrinogen synthase) (Hydroxymethylbilane synthase) (HMBS) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF PORPHOBILINOGEN DEAMINASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Porphobilinogen deaminase (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) (PBG-D) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Hmbs Isoform 1 of Porphobilinogen deaminase [rat-ipi-250309-contam.fasta] Isoform 1 of Porphobilinogen deaminase OS=Rattus norvegicus GN=Hmbs [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	361 amino acids
Gene Ontology:
Cellular Component:	condensed chromosome [IDA] nucleus [IDA] cytoplasm [UNKNOWN][IDA] mitochondrion [UNKNOWN][IEA]
Biological Process:	peptidyl-pyrromethane cofactor linkage [IEA] heme biosynthetic process [IEA] tetrapyrrole biosynthetic process [IDA][IEA][IMP]
Molecular Function:	carboxylic acid binding [IPI] coenzyme binding [IPI] hydroxymethylbilane synthase activity [UNKNOWN][IDA][IEA][IMP] amine binding [IPI] transferase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGNGGAATT AEENGSMMRV IRVGTRKSQL ARIQTDTVVA MLKTLYPGIQ FEIIAMSTTG  60
   61 DKILDTALSK IGEKSLFTKE LENALEKNEV DLVVHSLKDV PTILPPGFTI GAICKRENPC 120
  121 DAVVFHPKFI GKTLETLPEK SAVGTSSLRR VAQLQRKFPH LEFKSIRGNL NTRLRKLDEQ 180
  181 LEFSAIILAV AGLQRMGWQN RVGQILHPEE CMYAVGQGAL AVEVRAKDQD ILDLVGVLHD 240
  241 PETLLRCIAE RAFLRHLEGG CSVPVAVHTV MKDGQLYLTG GVWSLDGSDS MQETMQATIQ 300
  301 VPVQQEDGPE DDPQLVGITA RNIPRGAQLA AENLGISLAS LLLNKGAKNI LDVARQLNDV 360
  361 R

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: HEM3_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: