Protein Overview: PPA5_RAT

General Information:
Name(s) found:	PPA5_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|9506369\|ref\|NP_062017.1\| acid phosphatase 5 [Rattus norvegicus] [NCBI NR] gi\|6137538\|pdb\|1QHW\|A Chain A, Purple Acid Phosphatase From Rat Bone [NCBI NR] gi\|50926820\|gb\|AAH78847.1\| Acp5 protein [Rattus norvegicus] [NCBI NR] gi\|149020419\|gb\|EDL78224.1\| acid phosphatase 5, tartrate resistant, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|130723\|sp\|P29288.1\|PPA5_RAT RecName: Full=Tartrate-resistant acid phosphatase type 5; Short=TR-AP; AltName: Full=Tartrate-resistant acid ATPase; Short=TrATPase; AltName: Full=Acid phosphatase 5, tartrate resistant; Flags: Precursor [NCBI NR] pir\|\|A41720 acid phosphatase (EC 3.1.3.2) 5 precursor - rat [NCBI NR] Tartrate-resistant acid phosphatase type 5 OS=Rattus norvegicus GN=Acp5 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):None Tartrate-resistant acid phosphatase type 5 precursor [hmr_yeast5_DM3-1_pombe.fasta] acid phosphatase 5; Acid phosphatase 5, tartrate resistant; Acid phosphatase 5 tartrate resistant [HMR_022704-rand.fasta] acid phosphatase 5 [Rattus norvegicus]gi\|50926820\|gb\|AAH78847.1\| Acp5 protein [Rattus norvegicus]gi\|111328\|pir\|\|A41720 acid phosphatase (EC 3.1.3.2) 5 precursor - ratgi\|130723\|sp\|P29288\|PPA5_RAT Tartrate-resistant acid phosphatase type 5 precursor (TR- [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Tartrate-resistant acid phosphatase type 5 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_019144) acid phosphatase 5, tartrate resistant [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Chain A, Purple Acid Phosphatase From Rat Bone [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tartrate-resistant acid phosphatase type 5 precursor (TR-AP) (Tartrate-resistant acid ATPase) (TrATPase) (Acid phosphatase 5, tartrate resistant) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] acid phosphatase 5 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] acid phosphatase 5, tartrate resistant, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Acp5 protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Acp5 Tartrate-resistant acid phosphatase type 5 [rat-ipi-250309-contam.fasta] acid phosphatase 5, tartrate resistant precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Tartrate-resistant acid phosphatase type 5 OS=Rattus norvegicus GN=Acp5 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	327 amino acids
Gene Ontology:
Cellular Component:	extracellular space [IDA] integral to membrane [TAS] cytosol [UNKNOWN] lysosome [UNKNOWN][TAS]
Biological Process:	response to L-ascorbic acid [IEP] response to cytokine stimulus [UNKNOWN] response to zinc ion [IEP] negative regulation of cell adhesion [IDA] negative regulation of inflammatory response [UNKNOWN] negative regulation of interleukin-1 beta production [UNKNOWN] bone morphogenesis [UNKNOWN] response to organic cyclic substance [IEP] negative regulation of nitric oxide biosynthetic process [UNKNOWN] osteoclast differentiation [IEP] ossification [IEP] negative regulation of superoxide anion generation [UNKNOWN] bone resorption [UNKNOWN][IEP][TAS] multicellular organismal response to stress [IEP] response to lipopolysaccharide [UNKNOWN] negative regulation of interleukin-12 production [UNKNOWN] dephosphorylation [UNKNOWN] response to protein stimulus [IEP] negative regulation of tumor necrosis factor production [UNKNOWN] defense response to Gram-positive bacterium [UNKNOWN] positive regulation of cell migration [IMP] response to cholesterol [IEP]
Molecular Function:	ferric iron binding [UNKNOWN][ISS] ferrous iron binding [UNKNOWN][ISS] metal ion binding [IEA] acid phosphatase activity [UNKNOWN][IDA][TAS] hydrolase activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTWMVLLGL QILLLPLLAH CTAPASTLRF VAVGDWGGVP NAPFHTAREM ANAKEIARTV  60
   61 QIMGADFIMS LGDNFYFTGV HDANDKRFQE TFEDVFSDRA LRNIPWYVLA GNHDHLGNVS 120
  121 AQIAYSKISK RWNFPSPYYR LRFKVPRSNI TVAIFMLDTV MLCGNSDDFV SQQPEMPRDL 180
  181 GVARTQLSWL KKQLAAAKED YVLVAGHYPI WSIAEHGPTR CLVKNLRPLL AAYGVTAYLC 240
  241 GHDHNLQYLQ DENGVGYVLS GAGNFMDPSV RHQRKVPNGY LRFHYGSEDS LGGFTYVEIG 300
  301 SKEMSITYVE ASGKSLFKTS LPRRPRP

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: PPA5_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: