Protein Overview: DDC_RAT

General Information:
Name(s) found:	DDC_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6978759\|ref\|NP_036677.1\| dopa decarboxylase (aromatic L-amino acid decarboxylase) [Rattus norvegicus] [NCBI NR] pir\|\|DCRTA aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) - rat [NCBI NR] gi\|56541172\|gb\|AAH87032.1\| Dopa decarboxylase (aromatic L-amino acid decarboxylase) [Rattus norvegicus] [NCBI NR] gi\|493201\|gb\|AAA40646.1\| aromatic L-amino acid decarboxylase [NCBI NR] gi\|203950\|gb\|AAA41087.1\| dopa decarboxylase (EC 4.1.1.28) [NCBI NR] gi\|149016960\|gb\|EDL76065.1\| dopa decarboxylase, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149016959\|gb\|EDL76064.1\| dopa decarboxylase, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|118311\|sp\|P14173.1\|DDC_RAT RecName: Full=Aromatic-L-amino-acid decarboxylase; Short=AADC; AltName: Full=DOPA decarboxylase; Short=DDC [NCBI NR] Aromatic-L-amino-acid decarboxylase OS=Rattus norvegicus GN=Ddc PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):14-82043485 Aromatic-L-amino-acid decarboxylase [hmr_yeast5_DM3-1_pombe.fasta] dopa decarboxylase; Dopa decarboxylase (aromatic L-amino acid decarboxylase) [HMR_022704-rand.fasta] dopa decarboxylase [Rattus norvegicus]gi\|118311\|sp\|P14173\|DDC_RAT Aromatic-L-amino-acid decarboxylase (AADC) (DOPA decarboxylase) (DDC)gi\|68023\|pir\|\|DCRTA aromatic-L-amino-acid decarboxylase (EC 4.1.1.28) - ratgi\|203950\|gb\|AAA41087.1\| dopa decarboxylas [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Aromatic-L-amino-acid decarboxylase [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012545) dopa decarboxylase (aromatic L-amino acid decarboxylase) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Aromatic-L-amino-acid decarboxylase (AADC) (DOPA decarboxylase) (DDC) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] dopa decarboxylase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] dopa decarboxylase, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Dopa decarboxylase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] aromatic L-amino acid decarboxylase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] dopa decarboxylase (EC 4.1.1.28) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] dopa decarboxylase (aromatic L-amino acid decarboxylase) [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Ddc Aromatic-L-amino-acid decarboxylase [rat-ipi-250309-contam.fasta] aromatic-L-amino-acid decarboxylase [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta]
Organism:	Rattus norvegicus
Length:	480 amino acids
Gene Ontology:
Cellular Component:	intracellular [TAS]
Biological Process:	dopamine metabolic process [TAS] serotonin metabolic process [TAS] cellular amino acid and derivative metabolic process [IEA] carboxylic acid metabolic process [IEA] circadian rhythm [IEP] response to toxin [UNKNOWN][IEA] catecholamine biosynthetic process [TAS]
Molecular Function:	pyridoxal phosphate binding [IEA][TAS] protein binding [UNKNOWN][IEA] lyase activity [IEA] aromatic-L-amino-acid decarboxylase activity [UNKNOWN][IDA] carboxy-lyase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSREFRRRG KEMVDYIADY LDGIEGRPVY PDVEPGYLRA LIPTTAPQEP ETYEDIIRDI  60
   61 EKIIMPGVTH WHSPYFFAYF PTASSYPAML ADMLCGAIGC IGFSWAASPA CTELETVMMD 120
  121 WLGKMLELPE AFLAGRAGEG GGVIQGSASE ATLVALLAAR TKMIRQLQAA SPELTQAALM 180
  181 EKLVAYTSDQ AHSSVERAGL IGGVKIKAIP SDGNYSMRAA ALREALERDK AAGLIPFFVV 240
  241 VTLGTTSCCS FDNLLEVGPI CNQEGVWLHI DAAYAGSAFI CPEFRYLLNG VEFADSFNFN 300
  301 PHKWLLVNFD CSAMWVKKRT DLTEAFNMDP VYLRHSHQDS GLITDYRHWQ IPLGRRFRSL 360
  361 KMWFVFRMYG VKGLQAYIRK HVKLSHEFES LVRQDPRFEI CTEVILGLVC FRLKGSNQLN 420
  421 ETLLQRINSA KKIHLVPCRL RDKFVLRFAV CSRTVESAHV QLAWEHIRDL ASSVLRAEKE 480
  481

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.49

Protein Overview: DDC_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: