Protein Overview: AT12A_RAT

General Information:
Name(s) found:	AT12A_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	pir\|\|A42895 H+/K+-exchanging ATPase (EC 3.6.3.10) alpha chain, colon specific - rat [NCBI NR] gi\|2735426\|gb\|AAB93901.1\| H-K-ATPase alpha 2a subunit [Rattus norvegicus] [NCBI NR] gi\|203035\|gb\|AAA40779.1\| H+,K+-ATPase [Rattus norvegicus] [NCBI NR] gi\|19424160\|ref\|NP_598201.1\| hydrogen/potassium-exchanging ATPase 12A [Rattus norvegicus] [NCBI NR] gi\|1703464\|sp\|P54708.1\|AT12A_RAT RecName: Full=Potassium-transporting ATPase alpha chain 2; AltName: Full=Proton pump; AltName: Full=Non-gastric H(+)/K(+) ATPase subunit alpha [NCBI NR] (P54708) Potassium-transporting ATPase alpha chain 2 (EC 3.6.3.10) (Proton pump) (Non-gastric H(+)/K(+) ATPase alpha subunit) [Swiss-Prot] Potassium-transporting ATPase alpha chain 2 OS=Rattus norvegicus GN=Atp12a PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):15-34466188 Splice isoform Long of P54708 [hmr_yeast5_DM3-1_pombe.fasta] ATPase, H+/K+ transporting, nongastric, alpha polypeptide [HMR_022704-rand.fasta] ATPase, H+/K+ transporting, nongastric, alpha polypeptide [Rattus norvegicus]gi\|2735426\|gb\|AAB93901.1\| H-K-ATPase alpha 2a subunit [Rattus norvegicus]gi\|285388\|pir\|\|A42895 H+/K+-exchanging ATPase (EC 3.6.3.10) alpha chain, colon specific - ratgi\|203035 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform Long of Potassium-transporting ATPase alpha chain 2 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_133517) ATPase, H+/K+ transporting, nongastric, alpha polypeptide [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Potassium-transporting ATPase alpha chain 2 (Proton pump) (Non-gastric H(+)/K(+) ATPase subunit alpha) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] ATPase, H+/K+ transporting, nongastric, alpha polypeptide [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] H-K-ATPase alpha 2a subunit [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] H+,K+-ATPase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] hydrogen/potassium-exchanging ATPase 12A [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Atp12a Isoform Long of Potassium-transporting ATPase alpha chain 2 [rat-ipi-250309-contam.fasta] Isoform Long of Potassium-transporting ATPase alpha chain 2 OS=Rattus norvegicus GN=Atp12a [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1036 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [IEA] apical plasma membrane [IDA]
Biological Process:	potassium ion transport [NAS] proton transport [IEA] potassium ion homeostasis [UNKNOWN][IEA] metabolic process [IEA] response to metal ion [IDA] response to organic cyclic substance [IDA] metal ion transport [IDA] ATP biosynthetic process [IEA]
Molecular Function:	nucleotide binding [IEA] ATP binding [IEA] monovalent inorganic cation transmembrane transporter activity [IEA] metal ion binding [IEA] hydrogen:potassium-exchanging ATPase activity [IC][IDA][NAS] hydrolase activity [IEA] hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRKTEIYSV ELNGTKDVKP ADQRDDKKFK GAKNKDLEPN KSHEKEELKK ELDLDDHRLS  60
   61 NTELEQKYGT NIIQGLSSVR ATELLARDGP NTLTPPKQTP EIIKFLKQMV GGFSILLWIG 120
  121 AALCWIAFVI QYVNNSASLD NVYLGAILVL VVILTGIFAY YQEAKSTNIM ASFSKMIPQQ 180
  181 ALVIRDAEKK VISAEQLVVG DVVEIKGGDQ IPADIRLVFS QGCKVDNSSL TGESEPQARS 240
  241 TEFTHENPLE TKNIGFYSTT CLEGTATGIV INTGDRTIIG RIASLASGVG SEKTPIAIEI 300
  301 EHFVHIVAGV AVSIDIIFFI TAVCMKYYVL DAIIFLISII VANVPEGLLA TVTVTLSLTA 360
  361 KRMAKKNCLV KNLEAVETLG STSIICSDKT GTLTQNRMTV AHLWFDNQIF VADTSENQTK 420
  421 QAFDQSSGTW ASLSKIITLC NRAEFRPGQE SVPIMKRTVV GDASETALLK FSEVILGDVM 480
  481 GIRKRNHKVA EIPFNSTNKF QLSIHETEDP NNKRFLVVMK GAPERILEKC STIMINGQEQ 540
  541 PLDKSSADSF HTAYMELGGL GERVLGFCHL YLPAEQFPQS YIFDVDSVNF PTSNFCFVGL 600
  601 LSMIDPPRST VPDAVSKCRS AGIKVIMVTG DHPITAKAIA KSVGIISANN ETVEDIAKRR 660
  661 NIAVEQVNKR EAKAAVVTGM ELKDMTPEQL DELLTNYQEI VFARTSPQQK LIIVEGCQRQ 720
  721 DAIVAVTGDG VNDSPALKKA DIGIAMGIAG SDAAKNAADM VLLDDNFASI VTGVEEGRLI 780
  781 FDNLKKTIAY TLTKNIAELC PFLIYIVAGL PLPIGTITIL FIDLGTDIIP SIALAYEKAE 840
  841 SDIMNRKPRH KKKDRLVNTQ LAIYSYLHIG LMQALGGFLV YFTVYAQQGF WPTSLINLRV 900
  901 AWETDDINDL EDSYGQEWTR YQRKYLEWTG STAFFVAIMI QQIADLIIRK TRRNSIFQQG 960
  961 LFRNKVIWVG IASQVIVALI LSYGLGSVPA LSFTMLRVQY WFVAVPHAIL IWVYDEMRKL1020
 1021 FIRLYPGSWW DKNMYY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: AT12A_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: