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Protein Overview: gi|7259222

General Information:
Name(s) found: gi|7259222 [NCBI NR]
Description(s) found:
Found 3 descriptions.
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  • gi|7259222|emb|CAB77547.1| endothelial nitric oxide synthase 3 [Rattus norvegicus] [NCBI NR]
    • Organism: Rattus norvegicus
    Length: 306 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    caveola [UNKNOWN][IEA]
    soluble fraction [IDA]
    cytoskeleton [IEA]
    apical part of cell [IDA]
    cytoplasm [UNKNOWN][IDA]
    cytosol [UNKNOWN]
    Golgi membrane [UNKNOWN]
    Golgi apparatus [IDA]
    nucleolus [IDA]
    plasma membrane [IEA]
    Biological Process: response to cytokine stimulus [IEP]
    response to hyperoxia [IEP]
    negative regulation of muscle hyperplasia [IEA]
    response to lipoprotein stimulus [IEP]
    positive regulation of guanylate cyclase activity [UNKNOWN]
    response to amino acid stimulus [IEP]
    negative regulation of potassium ion transport [UNKNOWN][IEA]
    endothelial cell migration [UNKNOWN][IEA]
    positive regulation of angiogenesis [IEA]
    ovulation from ovarian follicle [UNKNOWN][IEA]
    response to ethanol [IEP]
    negative regulation of hydrolase activity [UNKNOWN][IEA]
    response to hypoxia [IEP]
    angiogenesis [UNKNOWN]
    negative regulation of smooth muscle cell proliferation [IMP]
    negative regulation of calcium ion transport [UNKNOWN][IEA]
    response to fluid shear stress [UNKNOWN][IEA]
    lung development [UNKNOWN][IEA]
    signal transduction [IMP]
    response to organic cyclic substance [IEP]
    regulation of systemic arterial blood pressure by endothelin [UNKNOWN][IEA]
    aging [IEP]
    response to peptide hormone stimulus [IEP]
    arginine catabolic process [UNKNOWN][IEA]
    regulation of sodium ion transport [UNKNOWN][IEA]
    blood vessel remodeling [IEA]
    regulation of blood vessel size [IEA]
    smooth muscle hyperplasia [IEA]
    response to drug [IEP]
    response to estradiol stimulus [IEP]
    lipopolysaccharide-mediated signaling pathway [UNKNOWN][IEA]
    response to lipopolysaccharide [IEP]
    oxidation reduction [IEA]
    nitric oxide biosynthetic process [UNKNOWN][IMP]
    response to lead ion [IEP]
    Molecular Function: arginine binding [UNKNOWN][IEA]
    calmodulin binding [IEA]
    tetrahydrobiopterin binding [UNKNOWN][IEA]
    NADP or NADPH binding [IEA]
    protein binding [UNKNOWN][IDA][IPI]
    nitric-oxide synthase activity [UNKNOWN][IDA][IMP]
    FMN binding [IEA]
    oxidoreductase activity [IEA]
    metal ion binding [IEA]
    FAD binding [IEA]
    actin monomer binding [UNKNOWN][IEA]
    heme binding [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKMFQATILS VENLQSSKST RATILVRLDT GSQEGLQYQP GDHIGVCPPN RPGLVEALLS  60
   61 RVEDPPPSTE PVAVEQLEKG SPGGPPPGWV RDPRLPPGTV RQALTYFLDI TSPPSPRLLR 120
  121 LLSTLAEESS EQQELEALSQ DPRRYEEWKW FRCPTLLEVL EQFPSVALPA PLILTQLPLL 180
  181 QPRYYSVSSA PSAHPGEIHL TVAVLAYRTQ DGLGPLHYGV CSTWMSQLKA GDPVPCFIRG 240
  241 APSFRLPPDP NLPCILVGPG TGIAPFRGFW QDRLHDIEIK GLQPAPMTLV FGCRCSQLDH 300
  301 LYRDEV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle