Protein Overview: ADAP2_RAT

General Information:
Name(s) found:	ADAP2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|9910340\|ref\|NP_064486.1\| ArfGAP with dual PH domains 2 [Rattus norvegicus] [NCBI NR] gi\|7636039\|emb\|CAB88403.1\| Centaurin-alpha2 protein [Rattus norvegicus] [NCBI NR] gi\|51315734\|sp\|Q9JK15.1\|ADAP2_RAT RecName: Full=Arf-GAP with dual PH domain-containing protein 2; AltName: Full=Centaurin-alpha-2 [NCBI NR] gi\|149053593\|gb\|EDM05410.1\| centaurin, alpha 2 [Rattus norvegicus] [NCBI NR] Centaurin-alpha-2 OS=Rattus norvegicus GN=Centa2 PE=1 SV=1 [Swiss-Prot] (Q9JK15) Centaurin alpha 2 [Swiss-Prot] Arf-GAP with dual PH domain-containing protein 2 OS=Rattus norvegicus GN=Adap2 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):10-65781124 Centaurin-alpha2 protein [hmr_yeast5_DM3-1_pombe.fasta] Centaurin-alpha2 protein [HMR_022704-rand.fasta] Centaurin-alpha2 protein [Rattus norvegicus]gi\|7636039\|emb\|CAB88403.1\| Centaurin-alpha2 protein [Rattus norvegicus]gi\|51315734\|sp\|Q9JK15\|CEA2_RAT Centaurin alpha 2 [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Centaurin-alpha 2 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_020101) Centaurin-alpha2 protein [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Centaurin alpha 2 [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] Centaurin-alpha-2 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] centaurin, alpha 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Centaurin-alpha2 protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 CENTAURIN ALPHA 2 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] ArfGAP with dual PH domains 2 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Centaurin-alpha 2 [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Adap2 Arf-GAP with dual PH domain-containing protein 2 [rat-ipi-250309-contam.fasta] Arf-GAP with dual PH domain-containing protein 2 OS=Rattus norvegicus GN=Adap2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	376 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] cytoplasm [UNKNOWN][ISS] cytosol [IDA] mitochondrial envelope [IDA] plasma membrane [UNKNOWN][ISS]
Biological Process:	heart development [UNKNOWN][ISS] regulation of ARF GTPase activity [IEA]
Molecular Function:	phosphatidylinositol-3,4,5-trisphosphate binding [UNKNOWN][IDA] phosphatidylinositol-4,5-bisphosphate binding [IDA] zinc ion binding [IEA] protein binding [UNKNOWN] ARF GTPase activator activity [IEA] metal ion binding [IEA] phosphatidylinositol-3,4-bisphosphate binding [IDA] inositol 1,3,4,5 tetrakisphosphate binding [UNKNOWN][ISS] phosphatidylinositol binding [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDRERNKKR LLELLQAAGT GNGHCADCGA ADPDWASYKL GVFICLHCSG VHRNFPDISK  60
   61 VKSVRLDFWD DSMVEFMTHN GNLSVKAKFE ARVPTFYYVP QASDCLVLKE QWIRAKYERQ 120
  121 EFMAEKAVSP PGDREGFLWK RGRDNSQFLR RRFVLLSREG LLKYYTKEEG KTPKAIINIK 180
  181 DLNATFQTEK IGHPHGLQIT YRKEGQTRNL FVYHDSGKEI VDWFNALRAA RLQYLKLAFP 240
  241 DLPESELVPL ITRNYLKQGF MEKTGPKHRE PFKKRWFALD PQERRLLYYK NPLDAFEQGQ 300
  301 VFLGSNEQGY EVWEGLPQGI RGNRWKVGLT VITPERKFVF TCPTEKEQRE WLESLRGVLS 360
  361 SPLSPLHLLT TSAKSG

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.71

Protein Overview: ADAP2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: