Protein Overview: PP2BB_RAT

General Information:
Name(s) found:	PP2BB_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8394033\|ref\|NP_058738.1\| protein phosphatase 3, catalytic subunit, beta [Rattus norvegicus] [NCBI NR] gi\|220716\|dbj\|BAA14084.1\| calcineurin A beta [Rattus norvegicus] [NCBI NR] gi\|203229\|gb\|AAA40848.1\| calcineurin A-beta [NCBI NR] gi\|129343\|sp\|P20651.1\|PP2BB_RAT RecName: Full=Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform; AltName: Full=Calmodulin-dependent calcineurin A subunit beta isoform; AltName: Full=CAM-PRP catalytic subunit [NCBI NR] pir\|\|A33794 phosphoprotein phosphatase (EC 3.1.3.16) 3-beta catalytic chain - rat [NCBI NR] Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform OS=Rattus norvegicus GN=Ppp3cb PE=1 SV=1 [Swiss-Prot] (P20651) Serine/threonine protein phosphatase 2B catalytic subunit, beta isoform (EC 3.1.3.16) (Calmodulin-dependent calcineurin A subunit, beta isoform) (CAM-PRP catalytic subunit) [Swiss-Prot] Ensembl_locations(Chr-bp):15-2092454;15-2092454 Serine/threonine protein phosphatase 2B catalytic subunit, beta isoform [hmr_yeast5_DM3-1_pombe.fasta] protein phosphatase 3, catalytic subunit, beta isoform; Calcineurin subunit A beta [HMR_022704-rand.fasta] protein phosphatase 3, catalytic subunit, beta isoform [Rattus norvegicus]gi\|129343\|sp\|P20651\|P2BB_RAT Serine/threonine protein phosphatase 2B catalytic subunit, beta isoform (Calmodulin-dependent calcineurin A subunit, beta isoform) (CAM-PRP catalytic s [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Serine/threonine protein phosphatase 2B catalytic subunit, beta isoform [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_017042) protein phosphatase 3, catalytic subunit, beta isoform; Calcineurin subunit A beta [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (Calmodulin-dependent calcineurin A subunit beta isoform) (CAM-PRP catalytic subunit) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] protein phosphatase 3, catalytic subunit, beta isoform [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] calcineurin A beta [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] calcineurin A-beta [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SERINE/THREONINE PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT, BETA ISOFORM [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Ppp3cb Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform [rat-ipi-250309-contam.fasta] Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform OS=Rattus norvegicus GN=Ppp3cb [011711_HMR.fasta] Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform OS=Rattus norvegicus GN=Ppp3cb PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	525 amino acids
Gene Ontology:
Cellular Component:	insoluble fraction [IDA] soluble fraction [IDA] protein complex [IDA]
Biological Process:	T cell differentiation [UNKNOWN][IEA] response to cytokine stimulus [UNKNOWN][IEA] heart development [UNKNOWN][IEA] muscle cell homeostasis [IEP] response to amphetamine [IEP] protein amino acid dephosphorylation [UNKNOWN][IDA] regulation of gene expression [UNKNOWN][IEA] negative regulation of T cell mediated cytotoxicity [UNKNOWN][IEA] T cell homeostasis [UNKNOWN][IEA]
Molecular Function:	protein serine/threonine phosphatase activity [UNKNOWN] phosphoprotein phosphatase activity [IEA] calmodulin binding [IDA] calcium-dependent protein serine/threonine phosphatase activity [IDA] protein binding [IPI] metal ion binding [IEA] protein heterodimerization activity [IDA] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAPEPARAA PPPPPPPPPP LGADRVVKAV PFPPTHRLTS EEVFDMDGIP RVDVLKNHLV  60
   61 KEGRVDEEIA LRIINEGAAI LRREKTMIEV EAPITVCGDI HGQFFDLMKL FEVGGSPANT 120
  121 RYLFLGDYVD RGYFSIECVL YLWVLKILYP STLFLLRGNH ECRHLTEYFT FKQECKIKYS 180
  181 ERVYEACMEA FDSLPLAALL NQQFLCVHGG LSPEIHTLDD IRRLDRFKEP PAFGPMCDLL 240
  241 WSDPSEDFGN EKSQEHFSHN TVRGCSYFYN YPAVCEFLQN NNLLSIIRAH EAQDAGYRMY 300
  301 RKSQTTGFPS LITIFSAPNY LDVYNNKAAV LKYENNVMNI RQFNCSPHPY WLPNFMDVFT 360
  361 WSLPFVGEKV TEMLVNVLSI CSDDELMTEG EDQFDVGSAA ARKEIIRNKI RAIGKMARVF 420
  421 SVLREESESV LTLKGLTPTG MLPSGVLAGG RQTLQSATVE AIEAEKAIRG SSPPHRICSF 480
  481 EEAKGLDRIN ERMPPRKDAV QQDGFNSLNT AHTTENHGTG NHSAQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: PP2BB_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: