Protein Overview: MFN1_RAT

General Information:
Name(s) found:	MFN1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|47605758\|sp\|Q8R4Z9.1\|MFN1_RAT RecName: Full=Mitofusin-1; AltName: Full=Transmembrane GTPase MFN1; AltName: Full=Mitochondrial transmembrane GTPase FZO1B [NCBI NR] gi\|20376820\|ref\|NP_620432.1\| mitofusin 1 [Rattus norvegicus] [NCBI NR] gi\|20269302\|dbj\|BAB90983.1\| mitochondrial transmembrane GTPase FZO1B [Rattus norvegicus] [NCBI NR] Mitofusin-1 OS=Rattus norvegicus GN=Mfn1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):2-108839155 Mitochondrial transmembrane GTPase FZO1B [hmr_yeast5_DM3-1_pombe.fasta] mitofusin 1; mitochondrial transmembrane GTPase FZO1B [HMR_022704-rand.fasta] mitofusin 1 [Rattus norvegicus]gi\|47605758\|sp\|Q8R4Z9\|MFN1_RAT Transmembrane GTPase MFN1 (Mitofusin 1) (Mitochondrial transmembrane GTPase FZO1B)gi\|20269302\|dbj\|BAB90983.1\| mitochondrial transmembrane GTPase FZO1B [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Transmembrane GTPase MFN1 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_138976) mitofusin 1; mitochondrial transmembrane GTPase FZO1B [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Mitofusin-1 (Transmembrane GTPase MFN1) (Mitochondrial transmembrane GTPase FZO1B) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] mitofusin 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] mitochondrial transmembrane GTPase FZO1B [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 TRANSMEMBRANE GTPASE MFN1 [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Transmembrane GTPase MFN1 (Mitofusin-1) (Mitochondrial transmembrane GTPase FZO1B) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Mfn1 Mitofusin-1 [rat-ipi-250309-contam.fasta] Mitofusin-1 OS=Rattus norvegicus GN=Mfn1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	741 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [UNKNOWN][IEA] membrane [IEA] integral to membrane [IEA] mitochondrial outer membrane [IEA]
Biological Process:	mitochondrial fusion [UNKNOWN][IEA]
Molecular Function:	nucleotide binding [IEA] GTP binding [IEA] protein binding [UNKNOWN] GTPase activity [IEA] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAETVSPLKH FVLAKKAITA IFGQLLEFVT EGSHFVEATY RNPELDRIAT EDDLVEIQGY  60
   61 RNKLAVIGEV LSRRHMKVAF FGRTSSGKSS VINAMLWDKV LPSGIGHTTN CFLSVEGTDG 120
  121 DKAYLMTEGS DEKKSVKTVN QLAHALHMDK DLKAGCLVHV FWPKAKCALL RDDLVLVDSP 180
  181 GTDVTTELDI WIDKFCLDAD VFVLVANSES TLMNTEKHFF HKVNERLSKP NIFILNNRWD 240
  241 ASASEPEYME DVRRQHMERC LHFLVEELKV VSPLEARNRI FFVSAKEVLN SRMNKAQGMP 300
  301 EGGGALAEGF QARLQEFQNF EQTFEECISQ SAVKTKFEQH TIRAKQILDT VKNILDSVNV 360
  361 AAAEKRVYSM EEREDQIDRL DFIRNQMNLL TMDVKKKIKE VTEEVANKVS CAMTDEICRL 420
  421 SVLVDEFCSE FHPTPSVLKV YKSELNKHIE DGMGRNLADR CTSEVNASIL QSQQEIIENL 480
  481 KPLLPAGIQN KLHTLIPCKK FDLSYDLNCH KLCSDFQEDI VFRFSLGWSS LVHRFLGSTN 540
  541 AQRVLLGLSE PIFQVPRSLA STPTAPSNPA APDNAAQEEL MITLITGLAS LTSRTSMGII 600
  601 VVGGVIWKTV GWKLISVTLS MYGALYLYER LTWTTRAKER AFKQQFVNYA TEKLQMIVKF 660
  661 TSANCSHQVQ QEMATTFARL CQQVDVTQKH LEEEIARLSK EIDQLEKIQN NSKLLRNKAV 720
  721 QLERELENFS KQFLHPSSGE S

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.65

Protein Overview: MFN1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: