Protein Overview: CSPG4_RAT

General Information:
Name(s) found:	CSPG4_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|8469184\|sp\|Q00657.2\|CSPG4_RAT RecName: Full=Chondroitin sulfate proteoglycan 4; AltName: Full=Chondroitin sulfate proteoglycan NG2; AltName: Full=HSN tumor-specific antigen; Flags: Precursor [NCBI NR] gi\|4468965\|emb\|CAA39884.2\| NG2 proteoglycan [Rattus norvegicus] [NCBI NR] gi\|13591932\|ref\|NP_112284.1\| chondroitin sulfate proteoglycan 4 [Rattus norvegicus] [NCBI NR] (Q00657) Chondroitin sulfate proteoglycan NG2 precursor (HSN tumor-specific antigen) [Swiss-Prot] Chondroitin sulfate proteoglycan 4 OS=Rattus norvegicus GN=Cspg4 PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):8-58952622 Chondroitin sulfate proteoglycan NG2 precursor [hmr_yeast5_DM3-1_pombe.fasta] membrane-spanning proteoglycan NG2 [HMR_022704-rand.fasta] membrane-spanning proteoglycan NG2 [Rattus norvegicus]gi\|4468965\|emb\|CAA39884.2\| NG2 proteoglycan [Rattus norvegicus]gi\|8469184\|sp\|Q00657\|PGG2_RAT Chondroitin sulfate proteoglycan NG2 precursor (HSN tumor-specific antigen) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Chondroitin sulfate proteoglycan 4 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_031022) membrane-spanning proteoglycan NG2 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Chondroitin sulfate proteoglycan NG2 precursor [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] Chondroitin sulfate proteoglycan 4 precursor (Chondroitin sulfate proteoglycan NG2) (HSN tumor-specific antigen) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] chondroitin sulfate proteoglycan 4 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] NG2 proteoglycan [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Cspg4 Chondroitin sulfate proteoglycan 4 [rat-ipi-250309-contam.fasta] Chondroitin sulfate proteoglycan 4 OS=Rattus norvegicus GN=Cspg4 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	2326 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [TAS] extracellular matrix [TAS] cell projection [IEA] plasma membrane [UNKNOWN][IEA] apical plasma membrane [IEA] lamellipodium membrane [IEA]
Biological Process:	cell proliferation [UNKNOWN][IEA] tissue remodeling [IEA] activation of MAPK activity [UNKNOWN][IEA] negative regulation of axonogenesis [TAS] angiogenesis [IEA] signal transduction [IEA] multicellular organismal development [IEA] neuron fate commitment [IEP] cell differentiation [IEA] transmembrane receptor protein tyrosine kinase signaling pathway [UNKNOWN][IEA] neuron remodeling [IDA] glial cell migration [UNKNOWN][IEA]
Molecular Function:	receptor signaling protein tyrosine phosphatase signaling protein activity [UNKNOWN] protein binding [UNKNOWN] collagen binding [IPI] signal transducer activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLSPGHPLS APALALILTL ALLVRSTAPA SFFGENHLEV PVPSALTRVD LLLQFSTSQP  60
   61 EALLLLAAGQ TDHLLLQLQS GHLQVRLALG QNELSLQTPA DTVLSDSTTH TVVLTVSNSW 120
  121 AVLSVDGVLN TSAPIPKASH LKVPYGLFVG SSGSLDLPYL KGISRPLRGC LHSAILNGRN 180
  181 LLRPLTPDVH EGCAEEFSAG DEVGLGFSGP HSLAAFPAWS TREEGTLEFT LTTRSQQAPL 240
  241 AFQAGDKRGN FIYVDIFEGH LRAVVEKGQG TMLLRNSVPV ADGQPHEVSV HIDVHRLEIS 300
  301 VDQYPTRTFN RGVLSYLEPR GSLLLGGLDT EASRHLQEHR LGLTPGAANI SLVGCIEDFS 360
  361 VNGRRLGLRD AWLTRDMAAG CRPEEDEYEE EVYGPFEAFS TLAPEAWPVM DLPEPCVPEP 420
  421 GLPAVFANFT QLLTISPLVV AEGGTAWLEW RHVQPTLDLT EAELRKSQVL FSVSQGARHG 480
  481 ELELDIPGAQ TRKMFTLLDV VNRKARFVHD GSEDTSDQLM LEVSVTSRAP VPSCLRRGQI 540
  541 YILPIQVNPV NDPPRIVFPH GSLMVILEHT QKPLGPEIFQ AYDPDSACEG LTIQLLGVSA 600
  601 SVPVEHRDQP GEPVTEFSCR DLEAGNIVYV HRGGPAQDLT FRVSDGMQAS GPATLKVVAV 660
  661 RPAIQILHNT GLRLAQGSAA AILPANLSVE TNAVGQDVSV LFRVTGTLQF GELQKQGAGG 720
  721 VEGTEWWDTL AFHQRDVEQG RVRYLSTDPQ HHTQDTVEDL TLEVQVGQET LSNLSFPVTI 780
  781 QRATVWMLQL EPLHTQNPHQ ETLTSAHLEA SLEEEGEGGP YPHIFHYELV QAPRRGNLLL 840
  841 QGTRLSDGQS FSQSDLQAGR VTYRATTRTS EAAEDSFRFR VTSPPHFSPL YTFPIHIGGD 900
  901 PNAPVLTNVL LMVPEGGEGV LSADHLFVKS LNSASYLYEV MEQPHHGSLA WRDPKGRATP 960
  961 VTSFTNEDLL HGRLVYQHDD SETIEDDIPF VATRQGEGSG DMAWEEVRGV FRVAIQPVND1020
 1021 HAPVQTISRV FHVARGGQRL LTTDDVAFSD ADSGFSDAQL VLTRKDLLFG SIVAMEEPTR1080
 1081 PIYRFTQEDL RKKQVLFVHS GADHGWLQLQ VSDGQHQATA MLEVQASEPY LHVANSSSLV1140
 1141 VPQGGQGTID TAVLHLDTNL DIRSGNEVHY HVTAGPHWGQ LLRDGQSVTS FSQRDLLDGA1200
 1201 ILYSHNGSLS PQDTLALSVA AGPVHTSTVL QVTIALEGPL APLQLVQHKR IYVFQGEAAE1260
 1261 IRRDQLEVVQ EAVLPADIMF SLRSPPNAGY LVMVSHGASA DGPPSLDPVQ RFSQEAINSG1320
 1321 RVLYLHSRPG AWSDSFSLDV ASGLGDPLEG ISVELEVLPT VIPLDVQNFS VPEGGTRTLA1380
 1381 PPLIQITGPY LGTLPGLVLQ VLEPPQHGAL QKEDRPQDGT LSTFSWREVE EQLIRYVHDG1440
 1441 SETQTDGFIL LANASEMDRQ SQPMAFTITI LPVNDQPPVI TTNTGLQIWE GAIVPIPPEA1500
 1501 LRGIDSDSGP EDLVYTIEQP SNGRIALRVA PDAEAHRFTQ AQLDSGLVLF SHRGALEGGF1560
 1561 HFDLSDGVHT SPGHFFRVVA QKQVLLSLEG SRKLTVCPES VQPLSSQSLS ASSSTGSDPR1620
 1621 HLLYQVVRGP QLGRLLHAQQ GSAEEALVNF TQAEVNAGNI LYEHEISSEP FWEAHDTIGL1680
 1681 LLSSSPARDL AATLAVTVSF DAACPQRPSR LWRNKGLWVP EGQRAKITVA ALDAANLLAS1740
 1741 VPASQRGRHD VLFQITQFPT RGQLLVSEEP LHARRPHFLQ SELTAGQLVY AHGGGGTQQD1800
 1801 GFRFRAHLQG PTGASVAGPQ TSEAFVITVR DVNERPPQPQ ASIPLRITRG SRAPVSRAQL1860
 1861 SVVDPDSAPG EIEYEVQRAP HNGFLSLAGD NTGPVTHFTQ ADVDAGRLAF VANGSSVAGV1920
 1921 FQLSMSDGAS PPIPMSLAVD VLPSTIEVQL RAPLEVPQAL GRSSLSRQQL QVISDREEPD1980
 1981 VAYRLTQGPL YGQVLVGGQP ASAFSQLQVD QGDVVFAFTN FSSSQDHFKV LALARGVNAS2040
 2041 ATVNVTVQAL LHVWAGGPWP QGTTLRLDPT VLDASELANR TGSMPRFRLL EGPRYGRVVR2100
 2101 VSQGRAESRT NQLVEDFTQQ DLEEGRLGLE VGRPEGRSTG PTGDRLTLEL QATGVPPAVA2160
 2161 LLDFATEPYH AAKFYKVTLL SVPEAARTET EKTGKSTPTG QPGQAASSPM PTVAKSGFLG2220
 2221 FLEANMFSVI IPVCLVLLLL ALILPLLFYL RKRNKTGKHD VQVLTAKPRN GLAGDTETFR2280
 2281 KVEPGQAIPL TTVPGQGPPP GGQPDPELLQ FCRTPNPALR NGQYWV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: CSPG4_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: