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Protein Overview: DYHC2_RAT

General Information:
Name(s) found: DYHC2_RAT [Swiss-Prot]
Description(s) found:
Found 17 descriptions.
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  • Cytoplasmic dynein 2 heavy chain 1 OS=Rattus norvegicus GN=Dync2h1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 4306 amino acids

    Gene Ontology:
    Cellular Component: cytoskeleton [IEA]
    cytoplasm [IEA]
    cilium axoneme [IEA]
    cilium [IEA]
    dynein complex [IEA]
    Golgi apparatus [UNKNOWN]
    plasma membrane [IEA]
    microtubule [IEA]
    Biological Process: embryonic limb morphogenesis [UNKNOWN]
    forebrain development [UNKNOWN]
    multicellular organismal development [IEA]
    Golgi organization [UNKNOWN]
    cell projection organization [IEA]
    cilium assembly [UNKNOWN]
    protein processing [UNKNOWN]
    microtubule-based movement [IEA]
    determination of left/right symmetry [UNKNOWN]
    asymmetric protein localization [UNKNOWN]
    dorsal/ventral pattern formation [UNKNOWN]
    Molecular Function: nucleotide binding [IEA]
    ATPase activity [IEA]
    ATP binding [IEA]
    microtubule motor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGSLSDVRK LFLFTTTQNY FGLRPELWDQ TPLSNCPEVN NFLDDGNQML LRVQRSDAGL  60
   61 AFSNTIDFDD TKDKVLVFFK LRPEVITDGN LHTNILVSSM LESPINSLYQ AVRQVFAPML 120
  121 LKDQEWSRNF DPKLQNLLSE LEAGLGVVLR KSDTNLPKLK LKEDDTRGIL TPSDEFQFWI 180
  181 EQAHRGSKQI SKERASYFKE LFETIAREFY NLDSLSLLEV VDLVETTRDV VDDVWRQAEH 240
  241 DHYPESRMLH LLDVIGGSFG RFVQKKLGSL KLWEDPYYLV KENLKAGISI CEQWVIVCSH 300
  301 LTGQVWQRYV PHPWKSEKYF PETLDRLGKR LEEVLAIRTI HEKLLYFLPA SEERIVCLSR 360
  361 VFEPFTGVNP VQYNPYTEPL WKAAVSQYEK IIAPAEQKIA GKLKNYISEI QDSPQQLLQA 420
  421 FLKYKELVKR PTISKELMLE RETLLARLGD SAKDFRLDFE NRCRGIPGDA SGPLSGKNLS 480
  481 EVVNNIVWVR QLELKVDDTI KIAEALLSDL SGFRSFHRSA EDLLDQFKLY EQEQFDDWSR 540
  541 EVQSGLSDSR SGLCIEANSR IMELDPNDGA LKVHYSDRLV ILLREVRQLS ALGFVIPAKI 600
  601 QQVANVAQKF CKQAIILKQV AHFYNSIDQQ MIQSQRPMML QSALAFEQII KNSKAGSGGK 660
  661 SQITWDNPKE LEGYIQKLQN AAERLATENR RLRKWHITFC EKVVILMNID LLRQQQRWKD 720
  721 GLQELRTGLA SVAAQGFQPS DMRAWRQHWN HQLYKALEHQ YQMGLEALNE NLPEINVDLT 780
  781 YKQGRLQFRP PFEEIRAKYY REMKRFIGIP NQFKGVGGAG DESIFSVMID RNASGFLTIY 840
  841 SKAEDLFRRL SAVLHQHKEW VVIGQVDMEA LVEKNLSTVH DWEKNFKALK IKGKEVERLP 900
  901 SAVKVDCLNI NCSPVKTVID DLIQKLFDLL VLSLKKSIQT HIHEIDTFVT EAMKVLTVIP 960
  961 QSVEEIGDTN LQYSNLQDRR PEILPLFQEA EDKNRLLRTV AGGGVETVSN LRAKWDKFEL1020
 1021 MMESHQLMIK DQIEVMKGNV KSRLQIYYQE LDKFKARWDQ LKPGDDIIET GQQNTMDQSA1080
 1081 KSIKEKKIEF DDLEVIRKKL VDDCHHFGLE ESNFSLAYSI SKDIESCAQI WALYEEFQQG1140
 1141 LQEMAKEDWI TYRTKIYIFE EFLINWHERL RKVEEHSVMT VKLQSEVDRY KIIIPILKYV1200
 1201 RGEHLSPDHW LDLFRLLGLP RGTSLEKLLF GDLLRVADTI VEKASDLKDL NSRAQGEVTI1260
 1261 REALRELDLW GVGAVFSLID YEDSQNRTIK LIKDWKDIVN QVGDNRCLLQ SLKDSPYYKG1320
 1321 FEDKVSIWER KLAQLDEYLQ NLNHIQRKWV YLEPIFGRGA LPKEQTRFNK VDEDFRSIMM1380
 1381 DIRKDSRVTT LTTHAGIRNT LLTILDQLQR CQKSLNEFLE EKRSAFPRFY FIGDDDLLEI1440
 1441 LGQSTNPSVI QSHLKKLFAG INSVCFDEES KHITAMRSLE GEVVPFKSKV LLSNNVEAWL1500
 1501 NDLALEMKQT LKQLLKECVT AGRSSQGAID PSLFPSQILC LAEQIKFTED VEDAIRDHSL1560
 1561 HQIEAQLAAK LERYTSVDTS SEDPGNSESG ILELKLKTLI LDIIHNIDIV KQLNQAQVHT1620
 1621 TDDWAWKKQV RFYMKSDHTC YVQMVDSELQ YTYEYQGNAP KLVYTPLTDK CYLTLTQAMK1680
 1681 MGLGGNPYGP AGTGKTESVK ALGGLLGRQV LVFNCDEGID VKSMGRIFVG LVKCGAWGCF1740
 1741 DEFNRLEEAV LSAVSMQIQT IQDALKNHRS VCELLGKEVE VNANSGIFIT MNPAGKGYGG1800
 1801 RQKLPDNLKQ LFRPVAMSRP DNDLIAEVIL YSEGFKDAKE LGRKLVAIFN LSRELLTPQQ1860
 1861 HYDWGLRALK TVLRGSGNLL RQLKKSGTKQ DVNENHIVVQ ALRLNTMSKF TFADCTRFDA1920
 1921 LIKDVFPGID FKEVEYNELS SALKQVFEEA NYEVIPNQMK KALELYEQLR QRTGVVIVGP1980
 1981 SGAGKSTLWR MLRAALCKIG KVVKQYTMNP KAMPRHQLLG HIDMDTREWS DGVLTNSARQ2040
 2041 VVREPQDVSS WIICDGDIDP EWIESLNSVL DDNRLLTMPS GERIQFGPNV NFVFETHDLS2100
 2101 CASPATISRM GMIFLSDEET DLNSLIKSWL RNQPVEYRSN LENWIGDYFS KALQWVLKQN2160
 2161 DYVVETSLVG TVMNGLSHLH GCKYHDQFII NLIRGLGGNL NMKSRLEFTK EVFNWARETP2220
 2221 PDSHRPMDTY FDCDRGQLAS YVLKKPESLT ADDFSSGHSL PVIQTPDMQR GLDYFKPWLS2280
 2281 SETKQPFILV GPEGCGKGML LRYAFSQLRS TEIATIHCSA QTTSRHLLQK LSQTCMVIST2340
 2341 NTGRVYRPKD CERLVLYLKD INLPKLDKWG TSTLVAFLQQ VLTYQGFYDE NLEWVGLENI2400
 2401 QIVASMSAGG RLGRHKLTTR FTSIVRLCAV DYPEREQLQT IYGAYLEAVL HKNLKNHSIW2460
 2461 GSSSKIYLLA GSMVQVYEQV RAKFTVDDYS HYFFTPCILT QWVLGLFRYD LEGGSSNHPL2520
 2521 DYVLEVVAYE ARRLFRDKIV GVKELHLFDN ILTSVLQGDW GSDILDNMAD SFYVTWGAQH2580
 2581 ISGAKIAPGQ PLPPHGKPLG KLSSADLKDV IKKGLIHYGR DNQNLDILLF QEVLEYMSRI2640
 2641 DRVLSFPGGS LLLAGRSGVG RRTVTSLVSH MHGAVLFSPK ISRGYEPKQF RTDLKHVLHL2700
 2701 AGIEAQQVVL LLEDYQFVHP TFLEMINSLL SSGEVPGLYT LEELEPLLLP LKDQASQDGF2760
 2761 FGPVFNYFTY RIQQNLHIVL IMDSANLNFI INCESNPALH KKCRVLWMEG WSDSSMKKIP2820
 2821 EMLFSEADIE EKYEKKRKDE KKKSSVDPDF IKSFLLIHES CKAYGATPSR YMTFLRVYSA2880
 2881 ISSSKRKELL KRQSHLQAGV SKLNEAKALV DELNRKAGEQ SILLRIKQDE ADSALQEITV2940
 2941 SMQDASEQKT ELERLKHRIA EEVVKIEERK SKIDDELKEV QPLVNEAKLA VGNIRPESLS3000
 3001 EIRSLRMPPD VIRDILEGVL RLMGIFDTSW VSMKSFLAKR GVREDIATFD ARNIPKEIRE3060
 3061 SVEELLFKNK ASFDPKNAKR ASTAAAPLAA WVKANVQYSH VLERIQPLET EQSGLELNLK3120
 3121 KTEDRKRKLE DLLNSVGQKV SELKEKFQSR TSEAAKLEAE VSKAQETIKA AEVLISQLDR3180
 3181 EHRRWNAQVA EIAEELATLP KRAQLAAAFI TYLSAAPEGL RKNCLEEWTK AAGLEKFDLR3240
 3241 RFLCTESEQL IWKSEGLPSD DLSIENALVI LQSRVCPFLI DPSSQATEWL KTHLKDSHLE3300
 3301 VINQQDSNFI TALELAVRFG KTLIIQEMDG VEPVLYPLLR RDLVAQGPRY VVQIGDKIID3360
 3361 YNEDFRLFLS TRNPNPFIPP DAASIVTEVN FTTTRSGLRG QLLALTIQHE KPDLEEQKTK3420
 3421 LLQQEEDKKI QLARLEESLL ETLATSQGNI LENKDLIESL NQTKASSALI QDSLKESYKL3480
 3481 QISLDRERDA YLPLAESASK MYFIISDLSK INNMYRFSLA SFLRLFQRAL QNKQDSESTE3540
 3541 QRIQCLVNSL KHMVYEYICR CLFKADQLMF ALHFVRGMHP EFFQENEWDT FTGVVVGDML3600
 3601 RKADSQQRIR DQLPSWIDQE RSWAVATLKI SLPGLYQTLC FEDGTLWRTY YHHSMCEQEF3660
 3661 PSILAKKVSL FQQVLVVQAL RPDRLQSAMA LFACKALGLK ELSPLPLNLK RLYKETLEIE3720
 3721 PILIIISPGA DPSQELQELA NAERSSERYH QVAMGQGQAD LAIQMLKECA RNGDWLCLKN3780
 3781 LHLVVSWLPV LEKELNTLQP KESFRLWLTA EVHPNFTPIL LQSSLKITYE SPPGLKKNLM3840
 3841 RTYESWTPEQ ISKKDNIHRA HALFSLAWFH AACQERRNFI PQGWTKFYEF SLSDLRAGYH3900
 3901 VIDRLFDGSK DVQWEFVHGL LENSIYGGRI DNYFDLRVLQ SYLKQFFNSS IIDVLNQRNK3960
 3961 KSIFPYSISL PDSCSILDYR AVIEKLPEDD KPSFFGLPAN IARSSQRMTS SQVISQLRIL4020
 4021 GRSVTAGCKF DREIWSNELS PVLNLWKKLN QNSNLIHQKV SPPNDRQGSP ILSFIILEQF4080
 4081 NAIRLVQSVH QSLAALSKVI RGTTLLSSEV QKLASALLNQ KCPLTWQSKW EGPEDPLQYL4140
 4141 RGLVARTLAI QNWVEKAEKQ ALLADTLDLS ELFHPDTFLN ALRQETARAT GCSVDSLKFV4200
 4201 ASWKGRLQEA KLQIKISGLL LEGCSFDGSR LSENQHDSPS VSSVLPCYMG WTPQGSYGPY4260
 4261 SPDECISLPV YTSAERDCVV TNIDVPCGGN QDQWIQCGAA LFLKNQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle