Protein Overview: ACHB4_RAT

General Information:
Name(s) found:	ACHB4_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|46371175\|gb\|AAS90356.1\| neuronal nicotinic acetylcholine receptor beta4 subunit [Rattus norvegicus] [NCBI NR] gi\|16258821\|ref\|NP_434693.1\| cholinergic receptor, nicotinic, beta 4 [Rattus norvegicus] [NCBI NR] gi\|149041721\|gb\|EDL95562.1\| cholinergic receptor, nicotinic, beta polypeptide 4 [Rattus norvegicus] [NCBI NR] gi\|1150981\|gb\|AAA85212.1\| nicotinic acetylcholine receptor subunit beta4 [NCBI NR] gi\|113111\|sp\|P12392.1\|ACHB4_RAT RecName: Full=Neuronal acetylcholine receptor subunit beta-4; AltName: Full=Neuronal acetylcholine receptor non-alpha-2 chain; Short=N-alpha 2; Flags: Precursor [NCBI NR] (P12392) Neuronal acetylcholine receptor protein, beta-4 chain precursor (Neuronal acetylcholine receptor non-alpha-2 chain) (N-alpha 2) [Swiss-Prot] Neuronal acetylcholine receptor subunit beta-4 OS=Rattus norvegicus GN=Chrnb4 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):8-56709953 Splice isoform Short of P12392 [hmr_yeast5_DM3-1_pombe.fasta] cholinergic receptor, nicotinic, beta polypeptide 4; Acetylcholine receptor beta 4 [HMR_022704-rand.fasta] cholinergic receptor, nicotinic, beta polypeptide 4 [Rattus norvegicus]gi\|113111\|sp\|P12392\|ACHP_RAT Neuronal acetylcholine receptor protein, beta-4 chain precursor (Neuronal acetylcholine receptor non-alpha-2 chain) (N-alpha 2)gi\|46371175\|gb\|AAS90356.1\| [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform Short of Neuronal acetylcholine receptor protein, beta-4 subunit precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_052806) cholinergic receptor, nicotinic, beta polypeptide 4; Acetylcholine receptor beta 4 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Splice Isoform Short of Neuronal acetylcholine receptor protein, beta-4 chain precursor [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] Neuronal acetylcholine receptor subunit beta-4 precursor (Neuronal acetylcholine receptor non-alpha-2 chain) (N-alpha 2) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] cholinergic receptor, nicotinic, beta polypeptide 4 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] neuronal nicotinic acetylcholine receptor beta4 subunit [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] nicotinic acetylcholine receptor subunit beta4 [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF NEURONAL ACETYLCHOLINE RECEPTOR PROTEIN, BETA-4 CHAIN PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] cholinergic receptor, nicotinic, beta 4 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Neuronal acetylcholine receptor protein subunit beta-4 precursor (Neuronal acetylcholine receptor non-alpha-2 chain) (N-alpha 2) [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Chrnb4 Isoform Short of Neuronal acetylcholine receptor subunit beta-4 [rat-ipi-250309-contam.fasta] cholinergic receptor, nicotinic, beta 4 precursor [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Isoform Short of Neuronal acetylcholine receptor subunit beta-4 OS=Rattus norvegicus GN=Chrnb4 [011711_HMR.fasta] Neuronal acetylcholine receptor subunit beta-4 OS=Rattus norvegicus GN=Chrnb4 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	495 amino acids
Gene Ontology:
Cellular Component:	membrane fraction [IDA] synaptosome [IDA] postsynaptic membrane [IEA] integral to membrane [IEA] cell junction [IEA] nicotinic acetylcholine-gated receptor-channel complex [UNKNOWN][IDA][TAS] synapse [IEA] plasma membrane [IEA]
Biological Process:	ion transport [IEA] locomotory behavior [UNKNOWN] regulation of membrane potential [UNKNOWN] behavioral response to nicotine [UNKNOWN] synaptic transmission involved in micturition [UNKNOWN] smooth muscle contraction [UNKNOWN] signal transduction [UNKNOWN] regulation of action potential [UNKNOWN] protein heterooligomerization [IDA] response to nicotine [UNKNOWN] regulation of smooth muscle contraction [UNKNOWN]
Molecular Function:	ion channel activity [IEA] nicotinic acetylcholine-activated cation-selective channel activity [IC][IEA] acetylcholine receptor activity [UNKNOWN] drug binding [IDA] extracellular ligand-gated ion channel activity [IEA] acetylcholine binding [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRGTPLLLVS LFSLLQDGDC RLANAEEKLM DDLLNKTRYN NLIRPATSSS QLISIRLELS  60
   61 LSQLISVNER EQIMTTSIWL KQEWTDYRLA WNSSCYEGVN ILRIPAKRVW LPDIVLYNNA 120
  121 DGTYEVSVYT NVIVRSNGSI QWLPPAIYKS ACKIEVKHFP FDQQNCTLKF RSWTYDHTEI 180
  181 DMVLKSPTAI MDDFTPSGEW DIVALPGRRT VNPQDPSYVD VTYDFIIKRK PLFYTINLII 240
  241 PCVLITSLAI LVFYLPSDCG EKMTLCISVL LALTFFLLLI SKIVPPTSLD IPLIGKYLLF 300
  301 TMVLVTFSIV TTVCVLNVHH RSPSTHTMAS WVKECFLHKL PTFLFMKRPG LEVSLVRVPH 360
  361 PSQLHLATAD TAATSALGPT SPSNLYGSSM YFVNPVPAAP KSAVSSHTAG LPRDARLRSS 420
  421 GRFREDLQEA LEGVSFIAQH LESDDRDQSV IEDWKFVAMV VDRLFLWVFV FVCILGTMGL 480
  481 FLPPLFQIHA PSKDS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ACHB4_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: