Protein Overview: NHRF2_RAT

General Information:
Name(s) found:	NHRF2_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|42559161\|sp\|Q920G2.1\|NHRF2_RAT RecName: Full=Na(+)/H(+) exchange regulatory cofactor NHE-RF2; Short=NHERF-2; AltName: Full=Tyrosine kinase activator protein 1; Short=TKA-1; AltName: Full=SRY-interacting protein 1; Short=SIP-1; AltName: Full=Solute carr [NCBI NR] gi\|20270217\|ref\|NP_446263.1\| solute carrier family 9 isoform 3 regulator 2 [Rattus norvegicus] [NCBI NR] gi\|15419607\|gb\|AAK97088.1\| sodium-hydrogen exchanger 3 regulatory factor 2 [Rattus norvegicus] [NCBI NR] Na(+)/H(+) exchange regulatory cofactor NHE-RF2 OS=Rattus norvegicus GN=Slc9a3r2 PE=1 SV=1 [Swiss-Prot] (Q920G2) Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY interacting protein 1) (SIP-1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KAR [Swiss-Prot] Ensembl_locations(Chr-bp):10-11953414 Sodium-hydrogen exchanger 3 regulatory factor 2 [hmr_yeast5_DM3-1_pombe.fasta] solute carrier family 9 isoform 3 regulator 2; sodium/hydrogen exchanger; NHE3 kinase A regulatory protein [HMR_022704-rand.fasta] solute carrier family 9 isoform 3 regulator 2 [Rattus norvegicus]gi\|15419607\|gb\|AAK97088.1\| sodium-hydrogen exchanger 3 regulatory factor 2 [Rattus norvegicus]gi\|42559161\|sp\|Q920G2\|NHR2_RAT Na(+)/H(+) exchange regulatory co-factor NHE-RF2 (NHERF-2) (Tyr [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_053811) solute carrier family 9 isoform 3 regulator 2; sodium/hydrogen exchanger; NHE3 kinase A regulatory protein [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Tax_Id=10116 Na [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (Tyrosine kinase activator protein 1) (TKA-1) (SRY-interacting protein 1) (SIP-1) (Solute carrier family 9 isoform A3 regulatory factor 2) (NHE3 kinase A regulatory protein E3KARP) (Sodium-hydrogen [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] sodium-hydrogen exchanger 3 regulatory factor 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 NA [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] solute carrier family 9 isoform 3 regulator 2 [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Slc9a3r2 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 [rat-ipi-250309-contam.fasta] Na(+)/H(+) exchange regulatory cofactor NHE-RF2 OS=Rattus norvegicus GN=Slc9a3r2 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	337 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN][IDA] cytoplasm [UNKNOWN][IMP] endomembrane system [IEA] plasma membrane [UNKNOWN][IMP] apical plasma membrane [UNKNOWN][IDA][IMP]
Biological Process:	inner ear development [IEP]
Molecular Function:	protein binding [UNKNOWN][IDA][IEA][IPI] protein C-terminus binding [UNKNOWN][IEA] channel regulator activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAPESLRPR LCRLVRGEQG YGFHLHGEKG RRGQFIRRVE PGSPAEAAAL RAGDRLVEVN  60
   61 GVNVEGETHH QVVHRIKAVE GQTQLLVVDK ETDEELCRRQ LTCTEEMAHR GLPPAHNPWE 120
  121 PKPDWACSGS LGSDTGHKDV NGPPRELRPR LCHLRRGPQG YGFNLHSDKS RPGQYIRSVD 180
  181 PGSPASLSGL RAQDRLIEVN GQNVEGLRHA EVVARIKAQE DEARLLVVDP ETDEHFKRLR 240
  241 VVPTEDHVEG PLPSPVTNGT SLAQLNGGSV CSSRSDLPGS EKDNEDGSAW KRDPFQESGL 300
  301 HLSPTAAEAK EKARATRVNK RAPQMDWNRK REIFSNF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: NHRF2_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: