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Protein Overview: APOC1_RAT

General Information:
Name(s) found: APOC1_RAT [Swiss-Prot]
Description(s) found:
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  • pir||S05307 apolipoprotein C-I precursor - rat [NCBI NR]
  • gi|71051103|gb|AAH98670.1| Apolipoprotein C-I [Rattus norvegicus] [NCBI NR]
  • gi|6978521|ref|NP_036956.1| apolipoprotein C-I precursor [Rattus norvegicus] [NCBI NR]
  • gi|55677|emb|CAA33536.1| apolipoprotein CI, preprotein [Rattus norvegicus] [NCBI NR]
  • gi|33187766|gb|AAP97737.1| liver regeneration-related protein LRRG04 [Rattus norvegicus] [NCBI NR]
  • gi|158517799|ref|NP_001103466.1| apolipoprotein C-I precursor [Rattus norvegicus] [NCBI NR]
  • gi|149056741|gb|EDM08172.1| apolipoprotein C-I, isoform CRA_a [Rattus norvegicus] [NCBI NR]
  • gi|149056739|gb|EDM08170.1| apolipoprotein C-I, isoform CRA_a [Rattus norvegicus] [NCBI NR]
  • gi|114018|sp|P19939.1|APOC1_RAT RecName: Full=Apolipoprotein C-I; Short=Apo-CI; Short=ApoC-I; AltName: Full=Liver regeneration-related protein LRRG04; Flags: Precursor [NCBI NR]
  • Apolipoprotein C-I OS=Rattus norvegicus GN=Apoc1 PE=3 SV=1 [Swiss-Prot]
  • (P19939) Apolipoprotein C-I precursor (Apo-CI) [Swiss-Prot]
  • Ensembl_locations(Chr-bp):1-75932228 Apolipoprotein C-I precursor [hmr_yeast5_DM3-1_pombe.fasta]
  • apolipoprotein C-I; Apolipoprotein C1 [HMR_022704-rand.fasta]
  • apolipoprotein C-I [Rattus norvegicus]gi|33187766|gb|AAP97737.1| liver regeneration-related protein LRRG04 [Rattus norvegicus]gi|55677|emb|CAA33536.1| apolipoprotein CI, preprotein [Rattus norvegicus]gi|114018|sp|P19939|APC1_RAT Apolipoprotein C-I prec [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Apolipoprotein C-I precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • (NM_012824) apolipoprotein C1 [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta]
  • Apolipoprotein C-I precursor (Apo-CI) (ApoC-I) (Liver regeneration-related protein LRRG04) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • apolipoprotein C-I precursor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • apolipoprotein C-I, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Apolipoprotein C-I [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • apolipoprotein CI, preprotein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • liver regeneration-related protein LRRG04 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 APOLIPOPROTEIN C-I PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Apolipoprotein C-I precursor (Apo-CI) (ApoC-I) [nr-271106-contam.fasta]
  • apolipoprotein C-I [Rattus norvegicus] [nr-271106-contam.fasta]
  • Tax_Id=10116 Gene_Symbol=Apoc1 Apolipoprotein C-I [rat-ipi-250309-contam.fasta]
  • Apolipoprotein C-I OS=Rattus norvegicus GN=Apoc1 [011711_HMR.fasta]
  • Apolipoprotein C-I OS=Rattus norvegicus GN=Apoc1 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
    • Organism: Rattus norvegicus
    Length: 88 amino acids

    Gene Ontology:
    Cellular Component: very-low-density lipoprotein particle [UNKNOWN][IDA]
    high-density lipoprotein particle [UNKNOWN][IDA]
    endoplasmic reticulum [UNKNOWN][IEA]
    extracellular region [IEA]
    cellular_component [ND]
    Biological Process: negative regulation of fatty acid biosynthetic process [UNKNOWN][IEA]
    chylomicron remnant clearance [UNKNOWN][IEA]
    cholesterol metabolic process [UNKNOWN][IEA]
    triglyceride metabolic process [UNKNOWN][IEA]
    lipoprotein metabolic process [TAS]
    negative regulation of lipid metabolic process [UNKNOWN]
    negative regulation of very-low-density lipoprotein particle clearance [UNKNOWN][IEA]
    negative regulation of lipoprotein lipase activity [UNKNOWN][IEA]
    negative regulation of phosphatidylcholine catabolic process [UNKNOWN][IEA]
    plasma lipoprotein particle remodeling [UNKNOWN]
    negative regulation of cholesterol transport [UNKNOWN][IEA]
    cholesterol efflux [UNKNOWN][IEA]
    negative regulation of receptor-mediated endocytosis [UNKNOWN][IEA]
    regulation of lipid transport [IDA]
    phospholipid efflux [UNKNOWN][IEA]
    negative regulation of lipid catabolic process [UNKNOWN]
    very-low-density lipoprotein particle clearance [UNKNOWN]
    Molecular Function: fatty acid binding [UNKNOWN][IEA]
    phospholipase inhibitor activity [UNKNOWN][IEA]
    lipase inhibitor activity [UNKNOWN]
    molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLFIALPVL IVVVAMALEG PAPAQAAPDF SSAMESLPDK LKEFGNTLED KARAAIEHIK  60
   61 QKEIMIKTRN WFSETLNKMK EKLKTTFA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..88] PSI-BLAST 14.69897 HUMAN APOLIPOPROTEIN C-I, NMR, 18 STRUCTURES


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle