Protein Overview: PRLR_RAT

General Information:
Name(s) found:	PRLR_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|2506457\|sp\|P05710.2\|PRLR_RAT RecName: Full=Prolactin receptor; Short=PRL-R; AltName: Full=Lactogen receptor; Flags: Precursor [NCBI NR] gi\|149027341\|gb\|EDL83008.1\| prolactin receptor, isoform CRA_c [Rattus norvegicus] [NCBI NR] gi\|149027340\|gb\|EDL83007.1\| prolactin receptor, isoform CRA_c [Rattus norvegicus] [NCBI NR] gi\|149027339\|gb\|EDL83006.1\| prolactin receptor, isoform CRA_c [Rattus norvegicus] [NCBI NR] gi\|149027338\|gb\|EDL83005.1\| prolactin receptor, isoform CRA_c [Rattus norvegicus] [NCBI NR] Prolactin receptor OS=Rattus norvegicus GN=Prlr PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):2-53339172 Splice isoform 1 of P05710 [hmr_yeast5_DM3-1_pombe.fasta] Prolactin receptor precursor (PRL-R) (Lactogen receptor) [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Prolactin receptor precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] prolactin receptor, isoform CRA_c [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF PROLACTIN RECEPTOR PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Prlr Isoform 1 of Prolactin receptor [rat-ipi-250309-contam.fasta] Isoform 1 of Prolactin receptor OS=Rattus norvegicus GN=Prlr [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	610 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [IEA] cell surface [UNKNOWN]
Biological Process:	activation of transmembrane receptor protein tyrosine kinase activity [UNKNOWN] regulation of epithelial cell differentiation [UNKNOWN] mammary gland alveolus development [UNKNOWN] lactation [UNKNOWN] prostate gland growth [UNKNOWN] regulation of cell adhesion [UNKNOWN] mammary gland epithelial cell differentiation [UNKNOWN] JAK-STAT cascade [UNKNOWN]
Molecular Function:	protein binding [UNKNOWN] metal ion binding [IEA] prolactin receptor activity [UNKNOWN][IMP] peptide hormone binding [UNKNOWN] receptor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSALAFVLL VLNISLLKGQ SPPGKPEIHK CRSPDKETFT CWWNPGTDGG LPTNYSLTYS  60
   61 KEGEKTTYEC PDYKTSGPNS CFFSKQYTSI WKIYIITVNA TNQMGSSSSD PLYVDVTYIV 120
  121 EPEPPRNLTL EVKQLKDKKT YLWVKWSPPT ITDVKTGWFT MEYEIRLKPE EAEEWEIHFT 180
  181 GHQTQFKVFD LYPGQKYLVQ TRCKPDHGYW SRWSQESSVE MPNDFTLKDT TVWIIVAILS 240
  241 AVICLIMVWA VALKGYSMMT CIFPPVPGPK IKGFDTHLLE KGKSEELLSA LGCQDFPPTS 300
  301 DCEDLLVEFL EVDDNEDERL MPSHSKEYPG QGVKPTHLDP DSDSGHGSYD SHSLLSEKCE 360
  361 EPQAYPPTLH IPEITEKPEN PEANIPPTVD PQSTNPNFHV DAPKSSTWPL LPGQHMPRSP 420
  421 YHSVADVCKL AGSPVNTLDS FLDKAEENVL KLSKALETGE EEVAEQKGAK SFPSDKQNTP 480
  481 WPLLQEKSPT VYVKPPDYVE IHKVNKDGVL SLFPKQRENN QTEKPGVPET SKEYAKVSGI 540
  541 TDNNILVLVP DSRAQNTALL EESAKKAPPS FEADQSEKDL ASFTATSSNR RLQLGRLDYL 600
  601 DPTCFMHSFH

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: PRLR_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: