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Protein Overview: INSL3_RAT

General Information:
Name(s) found: INSL3_RAT [Swiss-Prot]
Description(s) found:
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  • gi|34223712|sp|Q9WUK0.2|INSL3_RAT RecName: Full=Insulin-like 3; AltName: Full=Leydig insulin-like peptide; Short=Ley-I-L; AltName: Full=Relaxin-like factor; Contains: RecName: Full=Insulin-like 3 B chain; Contains: RecName: Full=Insulin-like 3 A chain; Fl [NCBI NR]
  • gi|26024191|ref|NP_446132.1| insulin-like 3 [Rattus norvegicus] [NCBI NR]
  • gi|23112178|gb|AAD33663.2| relaxin-like factor [Rattus norvegicus] [NCBI NR]
  • gi|149036094|gb|EDL90760.1| rCG38627, isoform CRA_a [Rattus norvegicus] [NCBI NR]
  • Insulin-like 3 OS=Rattus norvegicus GN=Insl3 PE=2 SV=2 [Swiss-Prot]
  • (Q9WUK0) Insulin-like 3 precursor (Leydig insulin-like peptide) (Ley-I-L) (Relaxin-like factor) [Swiss-Prot]
  • Ensembl_locations(Chr-bp):16-18816091 insulin-like 3 [hmr_yeast5_DM3-1_pombe.fasta]
  • insulin-like 3; Leydig insulin-like peptide; relaxin-like factor; Leydig insulin-like peptide relaxin-like factor [HMR_022704-rand.fasta]
  • insulin-like 3 [Rattus norvegicus]gi|23112178|gb|AAD33663.2| relaxin-like factor [Rattus norvegicus]gi|34223712|sp|Q9WUK0|INL3_RAT Insulin-like 3 precursor (Leydig insulin-like peptide) (Ley-I-L) (Relaxin-like factor) [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Insulin-like 3 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • Insulin-like 3 precursor (Leydig insulin-like peptide) (Ley-I-L) (Relaxin-like factor) [Contains: Insulin-like 3 B chain; Insulin-like 3 A chain] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • insulin-like 3 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • rCG38627, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • relaxin-like factor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 INSULIN-LIKE 3 PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Tax_Id=10116 Gene_Symbol=Insl3 Insulin-like 3 [rat-ipi-250309-contam.fasta]
  • Insulin-like 3 OS=Rattus norvegicus GN=Insl3 [011711_HMR.fasta]
    • Organism: Rattus norvegicus
    Length: 128 amino acids

    Gene Ontology:
    Cellular Component: extracellular space [IDA]
    perinuclear region of cytoplasm [IDA]
    extracellular region [UNKNOWN][IEA]
    Biological Process: inhibition of adenylate cyclase activity by G-protein signaling pathway [IDA]
    oocyte maturation [IDA]
    gonad development [TAS]
    male gonad development [UNKNOWN][IDA]
    in utero embryonic development [UNKNOWN][IEA]
    negative regulation of cell proliferation [IDA]
    negative regulation of apoptosis [IDA]
    positive regulation of cell proliferation [IDA]
    positive regulation of cAMP biosynthetic process [IDA]
    Molecular Function: G-protein-coupled receptor binding [IPI]
    hormone activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHALLLLLLL ALGSALRSPQ PPEARAKLCG HHLVRALVRV CGGPRWSPEA TQPVDTRDRE  60
   61 LLQWLEQRHL LHALVADADP ALDPDPALDP QLPHQASQRQ RRSVATNAVH RCCLTGCTQQ 120
  121 DLLGLCPH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..128] FFAS03 1.95 Insulin-like growth factor


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle