Protein Overview: SCF_RAT

General Information:
Name(s) found:	SCF_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|4106384\|gb\|AAD02827.1\| stem cell factor KL-1 precursor [Rattus norvegicus] [NCBI NR] gi\|33667068\|ref\|NP_068615.1\| kit ligand isoform 1 [Rattus norvegicus] [NCBI NR] gi\|22654283\|sp\|P21581.2\|SCF_RAT RecName: Full=Kit ligand; AltName: Full=C-kit ligand; AltName: Full=Stem cell factor; Short=SCF; AltName: Full=Mast cell growth factor; Short=MGF; AltName: Full=Hematopoietic growth factor KL; Flags: Precursor [NCBI NR] gi\|149067075\|gb\|EDM16808.1\| kit ligand [Rattus norvegicus] [NCBI NR] Kit ligand OS=Rattus norvegicus GN=Kitlg PE=1 SV=2 [Swiss-Prot] Ensembl_locations(Chr-bp):7-28991935 Splice isoform 1 of P21581 [hmr_yeast5_DM3-1_pombe.fasta] kit ligand; stem cell factor KL-1 precursor; stem cell factor KL-2 precursor [HMR_022704-rand.fasta] kit ligand [Rattus norvegicus]gi\|22654283\|sp\|P21581\|SCF_RAT Kit ligand precursor (C-kit ligand) (Stem cell factor) (SCF) (Mast cell growth factor) (MGF) (Hematopoietic growth factor KL)gi\|4106384\|gb\|AAD02827.1\| stem cell factor KL-1 precursor [Rattus no [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 1 of Kit ligand precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] kit ligand [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Kit ligand precursor (C-kit ligand) (Stem cell factor) (SCF) (Mast cell growth factor) (MGF) (Hematopoietic growth factor KL) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] stem cell factor KL-1 precursor [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SPLICE ISOFORM 1 OF KIT LIGAND PRECURSOR [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] kit ligand isoform 1 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Kitlg Isoform 1 of Kit ligand [rat-ipi-250309-contam.fasta] Isoform 1 of Kit ligand OS=Rattus norvegicus GN=Kitlg [011711_HMR.fasta] Isoform of P21581, Kit ligand OS=Rattus norvegicus GN=Kitlg PE=3 SV=2 [RAT.fasta.20160308]
Organism:	Rattus norvegicus
Length:	273 amino acids
Gene Ontology:
Cellular Component:	extracellular space [UNKNOWN][IEA] cytoskeleton [IEA] cytoplasm [IEA] membrane [IEA] integral to membrane [UNKNOWN][IEA] extracellular region [IEA] plasma membrane [UNKNOWN][IEA]
Biological Process:	positive regulation of MAP kinase activity [UNKNOWN][IEA] germ cell programmed cell death [UNKNOWN][IEA] positive regulation of cell proliferation [UNKNOWN][IDA] positive regulation of Ras protein signal transduction [UNKNOWN][IEA] cell adhesion [IEA] positive regulation of DNA replication [UNKNOWN] positive regulation of melanocyte differentiation [UNKNOWN][IEA] ovarian follicle development [IDA] positive regulation of myeloid leukocyte differentiation [UNKNOWN][IEA] neural crest cell migration [UNKNOWN][IEA] negative regulation of apoptosis [UNKNOWN][IEA] negative regulation of mast cell apoptosis [UNKNOWN][IEA] positive regulation of peptidyl-tyrosine phosphorylation [UNKNOWN][IEA] positive regulation of mast cell proliferation [UNKNOWN][IEA]
Molecular Function:	growth factor activity [IEA] identical protein binding [UNKNOWN] protein binding [UNKNOWN][IEA] stem cell factor receptor binding [UNKNOWN][IEA] cytokine activity [UNKNOWN][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKKTQTWIIT CIYLQLLLFN PLVKTQEICR NPVTDNVKDI TKLVANLPND YMITLNYVAG  60
   61 MDVLPSHCWL RDMVTHLSVS LTTLLDKFSN ISEGLSNYSI IDKLGKIVDD LVACMEENAP 120
  121 KNVKESLKKP ETRNFTPEEF FSIFNRSIDA FKDFMVASDT SDCVLSSTLG PEKDSRVSVT 180
  181 KPFMLPPVAA SSLRNDSSSS NRKAAKSPED PGLQWTAMAL PALISLVIGF AFGALYWKKK 240
  241 QSSLTRAVEN IQINEEDNEI SMLQQKEREF QEV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: SCF_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: