Protein Overview: HPRT_RAT

General Information:
Name(s) found:	HPRT_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|68534712\|gb\|AAH98629.1\| Hypoxanthine phosphoribosyltransferase 1 [Rattus norvegicus] [NCBI NR] gi\|56374\|emb\|CAA43997.1\| rat hypoxanthine-guanine phosphoribosyltransferase [Rattus norvegicus] [NCBI NR] gi\|51092266\|ref\|NP_036715.1\| hypoxanthine phosphoribosyltransferase 1 [Rattus norvegicus] [NCBI NR] gi\|2304983\|gb\|AAB65640.1\| hypoxanthine guanine phosphoribosyl transferase [Rattus norvegicus] [NCBI NR] gi\|204659\|gb\|AAA41350.1\| hypoxanthine phosphoribosyltransferase [NCBI NR] gi\|149029219\|gb\|EDL84492.1\| rCG47045, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|123501\|sp\|P27605.1\|HPRT_RAT RecName: Full=Hypoxanthine-guanine phosphoribosyltransferase; Short=HGPRTase; Short=HGPRT [NCBI NR] pir\|\|S18140 hypoxanthine phosphoribosyltransferase (EC 2.4.2.8) - rat [NCBI NR] Hypoxanthine-guanine phosphoribosyltransferase OS=Rattus norvegicus GN=Hprt1 PE=1 SV=1 [Swiss-Prot] Ensembl_locations(Chr-bp):X-41312482 Hypoxanthine-guanine phosphoribosyltransferase [hmr_yeast5_DM3-1_pombe.fasta] hypoxanthine guanine phosphoribosyl transferase; hypoxanthine phosphoribosyl transferase [071204_hmrz_cont.fasta] hypoxanthine guanine phosphoribosyl transferase [Rattus norvegicus]gi\|56374\|emb\|CAA43997.1\| rat hypoxanthine-guanine phosphoribosyltransferase [Rattus norvegicus]gi\|2304983\|gb\|AAB65640.1\| hypoxanthine guanine phosphoribosyl transferase [Rattus norvegicu [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Hypoxanthine-guanine phosphoribosyltransferase [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Hypoxanthine-guanine phosphoribosyltransferase (HGPRTase) (HGPRT) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Hypoxanthine guanine phosphoribosyl transferase 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] hypoxanthine guanine phosphoribosyl transferase 1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG47045, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rat hypoxanthine-guanine phosphoribosyltransferase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] hypoxanthine guanine phosphoribosyl transferase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] hypoxanthine phosphoribosyltransferase [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] hypoxanthine phosphoribosyltransferase 1 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Hypoxanthine-guanine phosphoribosyltransferase (HGPRT) (HGPRTase) [nr-271106-contam.fasta] Hypoxanthine guanine phosphoribosyl transferase [Rattus norvegicus] [nr-271106-contam.fasta] Hypoxanthine-guanine phosphoribosyltransferase OS=Rattus norvegicus GN=Hprt1 [011711_HMR.fasta] Isoform of P27605, Hypoxanthine-guanine phosphoribosyltransferase OS=Rattus norvegicus GN=Hprt1 PE=1 SV=3 [RAT.fasta.20160308]
Organism:	Rattus norvegicus
Length:	218 amino acids
Gene Ontology:
Cellular Component:	soluble fraction [IDA] cytoplasm [UNKNOWN][IEA] cytosol [UNKNOWN]
Biological Process:	cytolysis [UNKNOWN][IEA] dopamine metabolic process [UNKNOWN] purine nucleotide biosynthetic process [UNKNOWN] guanine salvage [UNKNOWN][IEA] nucleoside metabolic process [IEA] adenine salvage [UNKNOWN][IEA] purine ribonucleoside salvage [UNKNOWN][IEA] striatum development [UNKNOWN][IEA] central nervous system neuron development [UNKNOWN][IEA] behavior [UNKNOWN] positive regulation of dopamine metabolic process [UNKNOWN][IEA] cerebral cortex neuron differentiation [UNKNOWN][IEA] dendrite morphogenesis [UNKNOWN][IEA] grooming behavior [UNKNOWN][IEA] protein homotetramerization [UNKNOWN] response to amphetamine [UNKNOWN][IEA] lymphocyte proliferation [UNKNOWN][IEA] hypoxanthine metabolic process [UNKNOWN][IDA] adenine metabolic process [UNKNOWN][IEA]
Molecular Function:	magnesium ion binding [UNKNOWN] transferase activity, transferring glycosyl groups [IEA] identical protein binding [UNKNOWN][IEA] protein binding [UNKNOWN] protein homodimerization activity [UNKNOWN] metal ion binding [IEA] hypoxanthine phosphoribosyltransferase activity [UNKNOWN][IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTLSPSVVI SDDEPGYDLD LFCIPNHYAE DLEKVFIPHG LIMDRTERLA RDVMKEMGGH  60
   61 HIVALCVLKG GYKFFADLLD YIKALNRNSD RSIPMTVDFI RLKSYCNDQS TGDIKVIGGD 120
  121 DLSTLTGKNV LIVEDIIDTG KTMQTLLSLV KQYSPKMVKV ASLLVKRTSR SVGYRPDFVG 180
  181 FEIPDKFVVG YALDYNEHFR DLNHVCVISE SGKAKYKA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: HPRT_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: